What is Stiripentol
Stiripentol is a structurally unique oral antiepileptic indicated for the treatment of seizures associated with Dravet syndrome in patients 2 years and older who are also taking clobazam.
There are no clinical data to support stiripentol monotherapy in Dravet syndrome; trials have only documented efficacy when it is combined with clobazam and/or valproate
Brand Name
DIACOMIT
Indications
- Dravet syndrome
Side Effects
- agitation
- anorexia
- ataxia
- depression
- drowsiness
- dysarthria
- fatigue
- fever
- hypersalivation
- hypotonia
- infection
- insomnia
- nausea
- neutropenia
- pharyngitis
- suicidal ideation
- thrombocytopenia
- tremor
- vomiting
- weight gain
- weight loss
Monitoring Parameters
- CBC
- weight
Contraindications
- abrupt discontinuation
- breast-feeding
- children
- depression
- driving or operating machinery
- growth inhibition
- hepatic disease
- neutropenia
- phenylketonuria
- pregnancy
- renal disease
- renal failure
- renal impairment
- suicidal ideation
- thrombocytopenia
Interactions
No information is available regarding drug interactions associated with Stiripentol
