What is Sevelamer
Sevelamer is an oral phosphate binder indicated for the control of serum phosphorus in patients with chronic kidney disease on dialysis.
Brand Name
- RenaGel
- Renvela
Indications & Dosage
- hyperphosphatemia
For the treatment of hyperphosphatemia in patients with chronic kidney disease (CKD) on dialysis
Side Effects
- abdominal pain
- bowel necrosis
- colitis
- constipation
- diarrhea
- dyspepsia
- dysphagia
- flatulence
- folate deficiency
- GI bleeding
- GI obstruction
- GI perforation
- hyperkalemia
- ileus
- infection
- metabolic acidosis
- nausea
- pruritus
- rash
- vitamin D deficiency
- vitamin K deficiency
- vomiting
Monitoring Parameters
- serum 25(OH)hydroxyvitamin D concentrations
- serum bicarbonate
- serum chloride
- serum folate concentration
- serum phosphate
Contraindications
- breast-feeding
- constipation
- dysphagia
- GI obstruction
- pregnancy
- surgery
Interactions
- Ciprofloxacin
- Clonazepam
- Cyclosporine
- Delafloxacin
- Dichlorphenamide
- Erdafitinib
- Ethosuximide
- Gemifloxacin
- Ibritumomab Tiuxetan
- Levofloxacin
- Levothyroxine
- Levothyroxine; Liothyronine (Porcine)
- Levothyroxine; Liothyronine (Synthetic)
- Liothyronine
- Lithium
- Moxifloxacin
- Mycophenolate
- Norfloxacin
- Ofloxacin
- Phenytoin
- Phosphorated Carbohydrate Solution
- Phosphorus
- Potassium Phosphate
- Potassium Phosphate; Sodium Phosphate
- Procainamide
- Tacrolimus
- Theophylline, Aminophylline
- Thyroid hormones
