Acetaminophen Butalbital Caffeine

Acetaminophen Butalbital Caffeine Brand Names

Alagesic | Alagesic LQ | Americet | Anolor-300 | Arcet | BAC | CAPACET | Dolgic LQ | Dolgic Plus | Esgic | Esgic Plus | Ezol | Fioricet | Geone | Margesic | Medigesic | Orbivan | Pacaps | Phrenilin Forte | Repan | Tenake | Triad | Vanatol LQ | Vanatol S | Vtol LQ | Zebutal

What is Acetaminophen Butalbital Caffeine

Acetaminophen, butalbital, and caffeine are used together in an oral preparation to treat tension headaches, migraines, and mild to moderate pain in adult and pediatric patients 12 years and older, especially when antianxiety or relaxant effects are needed.

Acetaminophen is a non-salicylate analgesic, butalbital is a barbiturate, and caffeine is a methylxanthine CNS psychostimulant.

Treatment of multiple recurrent headaches with this combination has not been well studied and extended use of these products is not recommended. 

Indications

  • headache
  • migraine

NOTE: The FDA has advised healthcare professionals to discontinue prescribing and dispensing of combination prescription medications containing > 325 mg acetaminophen per dosage unit.

This action has been taken to reduce the risk of liver damage and severe hypersensitivity reactions associated with acetaminophen.

For the treatment of the symptom complex of tension headache or occasional migraine

Side Effects

  1. abdominal pain
  2. acneiform rash
  3. acute generalized exanthematous pustulosis (AGEP)
  4. agitation
  5. agranulocytosis
  6. anaphylactoid reactions
  7. angioedema
  8. anorexia
  9. anxiety
  10. confusion
  11. constipation
  12. contact dermatitis
  13. depression
  14. dizziness
  15. drowsiness
  16. dyspepsia
  17. dysphagia
  18. dyspnea
  19. edema
  20. elevated hepatic enzymes
  21. encephalopathy
  22. erythema
  23. erythema multiforme
  24. euphoria
  25. exfoliative dermatitis
  26. fatigue
  27. fever
  28. flatulence
  29. headache
  30. hemolysis
  31. hemolytic anemia
  32. hepatic necrosis
  33. hot flashes
  34. hyperglycemia
  35. hyperhidrosis
  36. hypoprothrombinemia
  37. increased urinary frequency
  38. insomnia
  39. interstitial nephritis
  40. irritability
  41. jaundice
  42. lethargy
  43. maculopapular rash
  44. methemoglobinemia
  45. musculoskeletal pain
  46. nasal congestion
  47. nausea
  48. neutropenia
  49. otalgia
  50. palpitations
  51. pancytopenia
  52. paresthesias
  53. photosensitivity
  54. physiological dependence
  55. polyuria
  56. pruritus
  57. psychological dependence
  58. ptosis
  59. purpura
  60. rash
  61. renal failure (unspecified)
  62. renal papillary necrosis
  63. renal tubular necrosis
  64. seizures
  65. sinus tachycardia
  66. syncope
  67. thrombocytopenia
  68. thrombocytosis
  69. tinnitus
  70. tolerance
  71. toxic epidermal necrolysis
  72. tremor
  73. urticaria
  74. vertigo
  75. vomiting
  76. withdrawal
  77. xerostomia

Monitoring Parameters

  • LFTs
  • serum creatinine/BUN: in chronic use or acute toxicity

Contraindications

  • abrupt discontinuation
  • acetaminophen hypersensitivity
  • acute abdomen
  • agranulocytosis
  • alcoholism
  • barbiturate hypersensitivity
  • breast-feeding
  • carbamazepine hypersensitivity
  • cardiac disease
  • children
  • chronic obstructive pulmonary disease (COPD)
  • CNS depression
  • coadministration with other CNS depressants
  • depression
  • driving or operating machinery
  • ethanol ingestion
  • ethanol intoxication
  • G6PD deficiency
  • geriatric
  • head trauma
  • hepatic disease
  • hepatitis
  • hepatotoxicity
  • hydantoin hypersensitivity
  • hypovolemia
  • infants
  • malnutrition
  • neonates
  • porphyria
  • potential for overdose or poisoning
  • pregnancy
  • pulmonary disease
  • renal failure
  • renal impairment
  • respiratory depression
  • seizure disorder
  • sleep apnea
  • substance abuse
  • suicidal ideation
  • tachycardia

Interactions

  • Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
  • Abemaciclib
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Codeine
  • Acetaminophen; Dextromethorphan; Doxylamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Diphenhydramine
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Pseudoephedrine
  • Acetaminophen; Tramadol
  • Acetazolamide
  • Aclidinium; Formoterol
  • Acrivastine; Pseudoephedrine
  • Adenosine
  • Albuterol
  • Albuterol; Ipratropium
  • Aldesleukin, IL-2
  • Alfentanil
  • Aliskiren; Amlodipine
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Alprazolam
  • Altretamine
  • Amantadine
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminosalicylate sodium, Aminosalicylic acid
  • Amiodarone
  • Amitriptyline; Chlordiazepoxide
  • Amlodipine
  • Amlodipine; Atorvastatin
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Amobarbital
  • Amoxapine
  • Amoxicillin; Clarithromycin; Lansoprazole
  • Amoxicillin; Clarithromycin; Omeprazole
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamine; Dextroamphetamine Salts
  • Amprenavir
  • Anagrelide
  • Antacids
  • Apomorphine
  • Apraclonidine
  • Apremilast
  • Aprepitant, Fosaprepitant
  • Arformoterol
  • Aripiprazole
  • Armodafinil
  • Artemether; Lumefantrine
  • Articaine; Epinephrine
  • Asenapine
  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
  • Atazanavir
  • Atazanavir; Cobicistat
  • Atenolol; Chlorthalidone
  • Atorvastatin
  • Atorvastatin; Ezetimibe
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Avanafil
  • Avapritinib
  • Avatrombopag
  • Axitinib
  • Azelastine
  • Azelastine; Fluticasone
  • Azilsartan; Chlorthalidone
  • Barbiturates
  • Bedaquiline
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Bendamustine
  • Bendroflumethiazide; Nadolol
  • Benzhydrocodone; Acetaminophen
  • Benzodiazepines
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzphetamine
  • Benztropine
  • Beta-agonists
  • Bicalutamide
  • Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
  • Bismuth Subsalicylate
  • Bismuth Subsalicylate; Metronidazole; Tetracycline
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Boceprevir
  • Bortezomib
  • Brexpiprazole
  • Brigatinib
  • Brimonidine
  • Brimonidine; Brinzolamide
  • Brimonidine; Timolol
  • Brivaracetam
  • Bromocriptine
  • Brompheniramine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Dextromethorphan; Guaifenesin
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide
  • Budesonide; Formoterol
  • Bupivacaine
  • Bupivacaine Liposomal
  • Bupivacaine; Lidocaine
  • Buprenorphine
  • Buprenorphine; Naloxone
  • Bupropion
  • Bupropion; Naltrexone
  • Buspirone
  • Busulfan
  • Butabarbital
  • Butorphanol
  • Caffeine
  • Calcifediol
  • Calcitriol
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Cannabidiol
  • Capmatinib
  • Captopril; Hydrochlorothiazide, HCTZ
  • Carbamazepine
  • Carbetapentane; Chlorpheniramine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Cariprazine
  • Cenobamate
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Cevimeline
  • Charcoal
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chlorambucil
  • Chloramphenicol
  • Chlordiazepoxide
  • Chlordiazepoxide; Clidinium
  • Chloroprocaine
  • Chlorothiazide
  • Chlorpheniramine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dextromethorphan
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Cholestyramine
  • Choline Salicylate; Magnesium Salicylate
  • Cimetidine
  • Cinacalcet
  • Ciprofloxacin
  • Citalopram
  • Clemastine
  • Clobazam
  • Clonazepam
  • Clorazepate
  • Clozapine
  • Cobimetinib
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • COMT inhibitors
  • Conjugated Estrogens
  • Conjugated Estrogens; Bazedoxifene
  • Conjugated Estrogens; Medroxyprogesterone
  • Cyclophosphamide
  • Cyclosporine
  • Cyproheptadine
  • Dapsone
  • Darifenacin
  • Darunavir
  • Darunavir; Cobicistat
  • Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
  • Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
  • Deflazacort
  • Delavirdine
  • Desloratadine; Pseudoephedrine
  • Deutetrabenazine
  • Dexamethasone
  • Dexchlorpheniramine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexmedetomidine
  • Dexmethylphenidate
  • Dextroamphetamine
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Dextromethorphan; Quinidine
  • Diazepam
  • Diclofenac
  • Diclofenac; Misoprostol
  • Dienogest; Estradiol valerate
  • Diethylpropion
  • Diethylstilbestrol, DES
  • Diflunisal
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diltiazem
  • Dimenhydrinate
  • Diphenhydramine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dipyridamole
  • Disopyramide
  • Disulfiram
  • Dobutamine
  • Dolutegravir; Rilpivirine
  • Donepezil
  • Donepezil; Memantine
  • Dopamine
  • Doravirine
  • Doravirine; Lamivudine; Tenofovir disoproxil fumarate
  • Doxercalciferol
  • Doxorubicin
  • Doxycycline
  • Doxylamine
  • Doxylamine; Pyridoxine
  • Dronabinol
  • Dronedarone
  • Droperidol
  • Drospirenone; Estradiol
  • Drospirenone; Ethinyl Estradiol
  • Drospirenone; Ethinyl Estradiol; Levomefolate
  • Dyphylline
  • Dyphylline; Guaifenesin
  • Echinacea
  • Efavirenz
  • Efavirenz; Emtricitabine; Tenofovir
  • Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
  • Elagolix; Estradiol; Norethindrone acetate
  • Elbasvir; Grazoprevir
  • Eltrombopag
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Emtricitabine; Rilpivirine; Tenofovir alafenamide
  • Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Encorafenib
  • Entacapone
  • Entrectinib
  • Ephedrine
  • Epinephrine
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Erdafitinib
  • Erlotinib
  • Erythromycin
  • Erythromycin; Sulfisoxazole
  • Escitalopram
  • Esketamine
  • Eslicarbazepine
  • Esomeprazole
  • Esomeprazole; Naproxen
  • Estazolam
  • Esterified Estrogens
  • Esterified Estrogens; Methyltestosterone
  • Estradiol
  • Estradiol Cypionate; Medroxyprogesterone
  • Estradiol; Levonorgestrel
  • Estradiol; Norethindrone
  • Estradiol; Norgestimate
  • Estradiol; Progesterone
  • Estrogens
  • Estropipate
  • Eszopiclone
  • Ethanol
  • Ethinyl Estradiol
  • Ethinyl Estradiol; Desogestrel
  • Ethinyl Estradiol; Ethynodiol Diacetate
  • Ethinyl Estradiol; Etonogestrel
  • Ethinyl Estradiol; Levonorgestrel
  • Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
  • Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
  • Ethinyl Estradiol; Norelgestromin
  • Ethinyl Estradiol; Norethindrone
  • Ethinyl Estradiol; Norethindrone Acetate
  • Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
  • Ethinyl Estradiol; Norethindrone; Ferrous fumarate
  • Ethinyl Estradiol; Norgestimate
  • Ethinyl Estradiol; Norgestrel
  • Ethosuximide
  • Exenatide
  • Ezetimibe; Simvastatin
  • Fedratinib
  • Felodipine
  • Fenoprofen
  • Fentanyl
  • Fesoterodine
  • Fexofenadine; Pseudoephedrine
  • Flibanserin
  • Fluconazole
  • Fluoxetine; Olanzapine
  • Fluticasone
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • Fluvoxamine
  • food
  • Formoterol
  • Formoterol; Mometasone
  • Fosamprenavir
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Gabapentin
  • Galantamine
  • Gallium Ga 68 Dotatate
  • General anesthetics
  • Givosiran
  • Glasdegib
  • Glimepiride
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glycopyrrolate; Formoterol
  • grapefruit juice
  • Green Tea
  • Griseofulvin
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Pseudoephedrine
  • Guanfacine
  • Haloperidol
  • Hemin
  • Homatropine; Hydrocodone
  • Hydantoins
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Hydroxyprogesterone
  • Hydroxyzine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Ifosfamide
  • Iloperidone
  • Imatinib
  • Indacaterol
  • Indacaterol; Glycopyrrolate
  • Indinavir
  • Insulin Glargine; Lixisenatide
  • Isavuconazonium
  • Isocarboxazid
  • Isoniazid, INH
  • Isoniazid, INH; Pyrazinamide, PZA; Rifampin
  • Isoniazid, INH; Rifampin
  • Isoproterenol
  • Isradipine
  • Itraconazole
  • Ivabradine
  • Ixabepilone
  • Ketoconazole
  • Ketoprofen
  • Lamivudine, 3TC; Zidovudine, ZDV
  • Lamotrigine
  • Lansoprazole
  • Lansoprazole; Naproxen
  • Lanthanum Carbonate
  • Lasmiditan
  • Lefamulin
  • Lemborexant
  • Lesinurad
  • Lesinurad; Allopurinol
  • Leucovorin
  • Levalbuterol
  • Levobupivacaine
  • Levocetirizine
  • Levoleucovorin
  • Levorphanol
  • Lidocaine
  • Lidocaine; Prilocaine
  • Linagliptin
  • Linagliptin; Metformin
  • Linezolid
  • Lisdexamfetamine
  • Lithium
  • Lixisenatide
  • Lofexidine
  • Lomitapide
  • Lopinavir; Ritonavir
  • Loratadine; Pseudoephedrine
  • Lorazepam
  • Lorlatinib
  • Lovastatin
  • Lovastatin; Niacin
  • Loxapine
  • Lumateperone
  • Lurasidone
  • Magnesium Salicylate
  • Magnesium Salts
  • Mannitol
  • Maprotiline
  • Mebendazole
  • Meclizine
  • Mefloquine
  • Melatonin
  • Meperidine
  • Meperidine; Promethazine
  • Mephobarbital
  • Mepivacaine
  • Mepivacaine; Levonordefrin
  • Meprobamate
  • Mestranol; Norethindrone
  • Metaproterenol
  • Metformin; Repaglinide
  • Methadone
  • Methamphetamine
  • Methazolamide
  • Methocarbamol
  • Methohexital
  • Methscopolamine
  • Methsuximide
  • Methyclothiazide
  • Methylphenidate
  • Methylprednisolone
  • Metoclopramide
  • Metolazone
  • Metronidazole
  • Metyrapone
  • Metyrosine
  • Mexiletine
  • Midazolam
  • Midodrine
  • Minocycline
  • Mipomersen
  • Mirtazapine
  • Mitotane
  • Modafinil
  • Monoamine oxidase inhibitors
  • Morphine
  • Morphine; Naltrexone
  • Nabilone
  • Nalbuphine
  • Nanoparticle Albumin-Bound Paclitaxel
  • Naproxen; Pseudoephedrine
  • Nelfinavir
  • Neratinib
  • Nevirapine
  • Niacin; Simvastatin
  • Nicardipine
  • Nifedipine
  • Nimodipine
  • Nintedanib
  • Nisoldipine
  • Non-Ionic Contrast Media
  • Norepinephrine
  • Obeticholic Acid
  • Olanzapine
  • Olaparib
  • Olodaterol
  • Ombitasvir; Paritaprevir; Ritonavir
  • Omeprazole
  • Omeprazole; Amoxicillin; Rifabutin
  • Omeprazole; Sodium Bicarbonate
  • Ondansetron
  • Oxazepam
  • Oxybutynin
  • Oxycodone
  • Oxymorphone
  • Paclitaxel
  • Paliperidone
  • Papaverine
  • Paroxetine
  • Peginterferon Alfa-2b
  • Pemigatinib
  • Pemoline
  • Penicillin G Benzathine; Penicillin G Procaine
  • Penicillin G Procaine
  • Pentazocine
  • Pentazocine; Naloxone
  • Pentobarbital
  • Perampanel
  • Perindopril; Amlodipine
  • Phendimetrazine
  • Phenelzine
  • Phenobarbital
  • Phenothiazines
  • Phentermine
  • Phentermine; Topiramate
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Pimavanserin
  • Pirbuterol
  • Pneumococcal Vaccine, Polyvalent
  • Pomalidomide
  • Posaconazole
  • Pralidoxime
  • Pramipexole
  • Pramlintide
  • Prednisolone
  • Prednisone
  • Pregabalin
  • Prilocaine
  • Prilocaine; Epinephrine
  • Primidone
  • Procarbazine
  • Progestins
  • Pseudoephedrine
  • Quazepam
  • Quetiapine
  • Quinidine
  • Quinine
  • Rabeprazole
  • Racepinephrine
  • Ramelteon
  • Ranolazine
  • Rasagiline
  • Red Yeast Rice
  • Regadenoson
  • Remifentanil
  • Repaglinide
  • Reserpine
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Rilpivirine
  • Riluzole
  • Rimegepant
  • Risperidone
  • Ritodrine
  • Ritonavir
  • Roflumilast
  • Romidepsin
  • Ropinirole
  • Ropivacaine
  • Rotigotine
  • Rucaparib
  • Safinamide
  • Salicylates
  • Salmeterol
  • Salsalate
  • Saquinavir
  • Scopolamine
  • Secobarbital
  • Segesterone Acetate; Ethinyl Estradiol
  • Selegiline
  • Selpercatinib
  • Selumetinib
  • Sertraline
  • Sildenafil
  • Simvastatin
  • Simvastatin; Sitagliptin
  • Siponimod
  • Sirolimus
  • Skeletal Muscle Relaxants
  • Sodium Bicarbonate
  • Sodium Oxybate
  • Solifenacin
  • Solriamfetol
  • Spironolactone
  • St. John’s Wort, Hypericum perforatum
  • Sufentanil
  • Sulfinpyrazone
  • Sunitinib
  • Suvorexant
  • Tacrolimus
  • Tapentadol
  • Tasimelteon
  • Tazemetostat
  • Telaprevir
  • Telotristat Ethyl
  • Temazepam
  • Terbinafine
  • Terbutaline
  • Teriflunomide
  • Tetrabenazine
  • Tetracaine
  • Thalidomide
  • Theophylline, Aminophylline
  • Thiabendazole
  • Thiazide diuretics
  • Thiopental
  • Thiothixene
  • Thyroid hormones
  • Tiotropium; Olodaterol
  • Tipranavir
  • Tizanidine
  • tobacco
  • Tolcapone
  • Tolterodine
  • Topiramate
  • Tramadol
  • Trandolapril; Verapamil
  • Tranylcypromine
  • Trazodone
  • Tretinoin, ATRA
  • Triamcinolone
  • Triazolam
  • Tricyclic antidepressants
  • Trimethobenzamide
  • Trimetrexate
  • Triprolidine
  • Ubrogepant
  • Ulipristal
  • Umeclidinium; Vilanterol
  • Valbenazine
  • Valerian, Valeriana officinalis
  • Valproic Acid, Divalproex Sodium
  • Vemurafenib
  • Verapamil
  • Vigabatrin
  • Vincristine
  • Vincristine Liposomal
  • Vorapaxar
  • Voriconazole
  • Vortioxetine
  • Voxelotor
  • Warfarin
  • Yohimbine
  • Zaleplon
  • Zanubrutinib
  • Ziconotide
  • Zidovudine, ZDV
  • Zileuton
  • Ziprasidone
  • Zolmitriptan
  • Zolpidem
  • Zonisamide
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