Acetaminophen Butalbital Caffeine Codeine

Acetaminophen Butalbital Caffeine Codeine Brand Names

  • Fioricet with Codeine
  • Phrenilin with Caffeine and Codeine

What is Acetaminophen Butalbital Caffeine Codeine

AAcetaminophen Butalbital Caffeine Codeine are used together in an oral preparation to treat occasional tension headaches, migraines, and mild to moderate pain, especially when antianxiety or relaxant effects are needed.

Treatment of multiple recurrent headaches with this combination has not been well studied; long-term use is not recommended.

According to published guidelines for the acute management of migraine, the use of butalbital-containing analgesics should be limited and carefully monitored due to concerns of overuse, medication-overuse headache, and withdrawal

Indications

  • headache
  • migraine
  • mild pain
  • moderate pain

Side Effects

  1. abdominal pain
  2. acneiform rash
  3. acute generalized exanthematous pustulosis (AGEP)
  4. adrenocortical insufficiency
  5. agitation
  6. agranulocytosis
  7. amenorrhea
  8. anaphylactic shock
  9. anaphylactoid reactions
  10. angioedema
  11. anorexia
  12. anxiety
  13. appetite stimulation
  14. bleeding
  15. chest pain (unspecified)
  16. confusion
  17. constipation
  18. contact dermatitis
  19. depression
  20. diarrhea
  21. dizziness
  22. drowsiness
  23. dysarthria
  24. dyspepsia
  25. dysphagia
  26. dyspnea
  27. edema
  28. emotional lability
  29. encephalopathy
  30. epistaxis
  31. erythema
  32. erythema multiforme
  33. esophagitis
  34. euphoria
  35. exfoliative dermatitis
  36. fatigue
  37. fever
  38. flatulence
  39. flushing
  40. gonadal suppression
  41. hallucinations
  42. headache
  43. hemolysis
  44. hemolytic anemia
  45. hepatic necrosis
  46. hepatotoxicity
  47. hiccups
  48. hot flashes
  49. hyperactivity
  50. hyperglycemia
  51. hyperhidrosis
  52. hypersalivation
  53. hyponatremia
  54. hypotension
  55. impotence (erectile dysfunction)
  56. increased urinary frequency
  57. infertility
  58. insomnia
  59. interstitial nephritis
  60. irritability
  61. jaundice
  62. lethargy
  63. libido decrease
  64. libido increase
  65. maculopapular rash
  66. methemoglobinemia
  67. miosis
  68. musculoskeletal pain
  69. nasal congestion
  70. nausea
  71. neonatal opioid withdrawal syndrome
  72. otalgia
  73. palpitations
  74. pancytopenia
  75. paresthesias
  76. peptic ulcer
  77. peripheral neuropathy
  78. photosensitivity
  79. physiological dependence
  80. polyuria
  81. pruritus
  82. psychological dependence
  83. psychosis
  84. ptosis
  85. purpura
  86. rash
  87. renal failure (unspecified)
  88. renal papillary necrosis
  89. renal tubular necrosis
  90. respiratory arrest
  91. respiratory depression
  92. restlessness
  93. seizures
  94. serotonin syndrome
  95. SIADH
  96. sinus tachycardia
  97. syncope
  98. thrombocytopenia
  99. thrombocytosis
  100. tinnitus
  101. tolerance
  102. toxic epidermal necrolysis
  103. tremor
  104. urinary retention
  105. urticaria
  106. vertigo
  107. vomiting
  108. withdrawal
  109. xerostomia

Monitoring Parameters

  • LFTs
  • serum creatinine/BUN: in chronic use or acute toxicity

Contraindications

  • abrupt discontinuation
  • accidental exposure
  • acetaminophen hypersensitivity
  • acute abdomen
  • adenoidectomy
  • adrenal insufficiency
  • agranulocytosis
  • alcoholism
  • anemia
  • anticoagulant therapy
  • Asian patients
  • asthma
  • barbiturate hypersensitivity
  • biliary tract disease
  • Black patients
  • bladder obstruction
  • bone marrow suppression
  • breast-feeding
  • carbamazepine hypersensitivity
  • cardiac disease
  • Caucasian patients
  • children
  • chronic obstructive pulmonary disease (COPD)
  • CNS depression
  • coadministration with other CNS depressants
  • constipation
  • depression
  • diabetes mellitus
  • driving or operating machinery
  • ethanol ingestion
  • ethanol intoxication
  • exfoliative dermatitis
  • G6PD deficiency
  • geriatric
  • GI obstruction
  • head trauma
  • hepatic disease
  • hepatic encephalopathy
  • hepatitis
  • hepatotoxicity
  • Hispanic patients
  • hydantoin hypersensitivity
  • hypothyroidism
  • ileus
  • immunosuppression
  • increased intracranial pressure
  • infants
  • infection
  • labor
  • MAOI therapy
  • mental status changes
  • myxedema
  • neonatal opioid withdrawal syndrome
  • neonates
  • neuromuscular disease
  • obesity
  • obstetric delivery
  • oliguria
  • opiate agonist hypersensitivity
  • osteomalacia
  • osteoporosis
  • pain
  • porphyria
  • potential for overdose or poisoning
  • pregnancy
  • prostatic hypertrophy
  • pulmonary disease
  • respiratory depression
  • respiratory infection
  • seizure disorder
  • seizures
  • sleep apnea
  • status asthmaticus
  • status epilepticus
  • substance abuse
  • suicidal ideation
  • thyroid disease
  • tonsillectomy
  • urethral stricture
  • urinary retention
  • urinary tract obstruction

Interactions

  • Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
  • Abemaciclib
  • Abiraterone
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Dextromethorphan
  • Acetaminophen; Dextromethorphan; Doxylamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Diphenhydramine
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Pseudoephedrine
  • Acetaminophen; Tramadol
  • Acetazolamide
  • Aclidinium; Formoterol
  • Acrivastine; Pseudoephedrine
  • Adenosine
  • Albuterol
  • Albuterol; Ipratropium
  • Aldesleukin, IL-2
  • Alfentanil
  • Aliskiren; Amlodipine
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Almotriptan
  • Alosetron
  • Alprazolam
  • Altretamine
  • Alvimopan
  • Amantadine
  • Amide local anesthetics
  • Amifampridine
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminosalicylate sodium, Aminosalicylic acid
  • Amiodarone
  • Amitriptyline
  • Amitriptyline; Chlordiazepoxide
  • Amlodipine
  • Amlodipine; Atorvastatin
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Amobarbital
  • Amoxapine
  • Amoxicillin; Clarithromycin; Lansoprazole
  • Amoxicillin; Clarithromycin; Omeprazole
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamine; Dextroamphetamine Salts
  • Amprenavir
  • Anagrelide
  • Antacids
  • Anticholinergics
  • Apalutamide
  • Apomorphine
  • Apraclonidine
  • Apremilast
  • Aprepitant, Fosaprepitant
  • Arformoterol
  • Aripiprazole
  • Armodafinil
  • Artemether; Lumefantrine
  • Articaine; Epinephrine
  • Asenapine
  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
  • Atazanavir
  • Atazanavir; Cobicistat
  • Atenolol; Chlorthalidone
  • Atorvastatin
  • Atorvastatin; Ezetimibe
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Avanafil
  • Avapritinib
  • Avatrombopag
  • Axitinib
  • Azelastine
  • Azelastine; Fluticasone
  • Azilsartan; Chlorthalidone
  • Baclofen
  • Barbiturates
  • Bedaquiline
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Bendamustine
  • Bendroflumethiazide; Nadolol
  • Benzhydrocodone; Acetaminophen
  • Benzodiazepines
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzonatate
  • Benzphetamine
  • Benztropine
  • Beta-agonists
  • Bethanechol
  • Bexarotene
  • Bicalutamide
  • Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
  • Bismuth Subsalicylate
  • Bismuth Subsalicylate; Metronidazole; Tetracycline
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Boceprevir
  • Bortezomib
  • Bosentan
  • Brexpiprazole
  • Brigatinib
  • Brimonidine
  • Brimonidine; Brinzolamide
  • Brimonidine; Timolol
  • Brivaracetam
  • Bromocriptine
  • Brompheniramine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Dextromethorphan; Guaifenesin
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide
  • Budesonide; Formoterol
  • Bumetanide
  • Bupivacaine
  • Bupivacaine Liposomal
  • Bupivacaine; Lidocaine
  • Buprenorphine
  • Buprenorphine; Naloxone
  • Bupropion
  • Bupropion; Naltrexone
  • Buspirone
  • Busulfan
  • Butabarbital
  • Butorphanol
  • Caffeine
  • Calcifediol
  • Calcitriol
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Cannabidiol
  • Capmatinib
  • Capsaicin; Metaxalone
  • Captopril; Hydrochlorothiazide, HCTZ
  • Carbamazepine
  • Carbetapentane; Chlorpheniramine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Cariprazine
  • Carisoprodol
  • Celecoxib
  • Cenobamate
  • Ceritinib
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Cevimeline
  • Charcoal
  • Chlophedianol; Dexbrompheniramine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chloral Hydrate
  • Chlorambucil
  • Chloramphenicol
  • Chlorcyclizine
  • Chlordiazepoxide
  • Chlordiazepoxide; Clidinium
  • Chloroprocaine
  • Chlorothiazide
  • Chlorpheniramine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dextromethorphan
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorpromazine
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Chlorzoxazone
  • Cholestyramine
  • Choline Salicylate; Magnesium Salicylate
  • Cimetidine
  • Cinacalcet
  • Ciprofloxacin
  • Citalopram
  • Clarithromycin
  • Clemastine
  • Clobazam
  • Clomipramine
  • Clonazepam
  • Clonidine
  • Clopidogrel
  • Clorazepate
  • Clozapine
  • Cobicistat
  • Cobimetinib
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • COMT inhibitors
  • Conivaptan
  • Conjugated Estrogens
  • Conjugated Estrogens; Bazedoxifene
  • Conjugated Estrogens; Medroxyprogesterone
  • Crizotinib
  • Crofelemer
  • Cyclizine
  • Cyclobenzaprine
  • Cyclophosphamide
  • Cyclosporine
  • Cyproheptadine
  • Dabrafenib
  • Dacomitinib
  • Dalfopristin; Quinupristin
  • Danazol
  • Dantrolene
  • Dapsone
  • Darifenacin
  • Darunavir
  • Darunavir; Cobicistat
  • Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
  • Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
  • Deflazacort
  • Delavirdine
  • Desflurane
  • Desipramine
  • Desloratadine; Pseudoephedrine
  • Desmopressin
  • Desvenlafaxine
  • Deutetrabenazine
  • Dexamethasone
  • Dexchlorpheniramine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexmedetomidine
  • Dexmethylphenidate
  • Dexpanthenol
  • Dextroamphetamine
  • Dextromethorphan
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Guaifenesin
  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Dextromethorphan; Guaifenesin; Potassium Guaiacolsulfonate
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Dextromethorphan; Promethazine
  • Dextromethorphan; Quinidine
  • Diazepam
  • Diclofenac
  • Diclofenac; Misoprostol
  • Dienogest; Estradiol valerate
  • Diethylpropion
  • Diethylstilbestrol, DES
  • Diflunisal
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diltiazem
  • Dimenhydrinate
  • Diphenhydramine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dipyridamole
  • Disopyramide
  • Disulfiram
  • Dobutamine
  • Dolasetron
  • Dolutegravir; Rilpivirine
  • Donepezil
  • Donepezil; Memantine
  • Dopamine
  • Doravirine
  • Doravirine; Lamivudine; Tenofovir disoproxil fumarate
  • Doxepin
  • Doxercalciferol
  • Doxorubicin
  • Doxycycline
  • Doxylamine
  • Doxylamine; Pyridoxine
  • Dronabinol
  • Dronedarone
  • Droperidol
  • Drospirenone; Estradiol
  • Drospirenone; Ethinyl Estradiol
  • Drospirenone; Ethinyl Estradiol; Levomefolate
  • Duloxetine
  • Dyphylline
  • Dyphylline; Guaifenesin
  • Echinacea
  • Efavirenz
  • Efavirenz; Emtricitabine; Tenofovir
  • Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
  • Elagolix
  • Elagolix; Estradiol; Norethindrone acetate
  • Elbasvir; Grazoprevir
  • Eletriptan
  • Eliglustat
  • Eltrombopag
  • Eluxadoline
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Emtricitabine; Rilpivirine; Tenofovir alafenamide
  • Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Encorafenib
  • Enflurane
  • Entacapone
  • Entrectinib
  • Enzalutamide
  • Ephedrine
  • Epinephrine
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Erdafitinib
  • Erlotinib
  • Erythromycin
  • Erythromycin; Sulfisoxazole
  • Escitalopram
  • Esketamine
  • Eslicarbazepine
  • Esomeprazole
  • Esomeprazole; Naproxen
  • Estazolam
  • Esterified Estrogens
  • Esterified Estrogens; Methyltestosterone
  • Estradiol
  • Estradiol Cypionate; Medroxyprogesterone
  • Estradiol; Levonorgestrel
  • Estradiol; Norethindrone
  • Estradiol; Norgestimate
  • Estradiol; Progesterone
  • Estrogens
  • Estropipate
  • Eszopiclone
  • Ethacrynic Acid
  • Ethanol
  • Ethinyl Estradiol
  • Ethinyl Estradiol; Desogestrel
  • Ethinyl Estradiol; Ethynodiol Diacetate
  • Ethinyl Estradiol; Etonogestrel
  • Ethinyl Estradiol; Levonorgestrel
  • Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
  • Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
  • Ethinyl Estradiol; Norelgestromin
  • Ethinyl Estradiol; Norethindrone
  • Ethinyl Estradiol; Norethindrone Acetate
  • Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
  • Ethinyl Estradiol; Norethindrone; Ferrous fumarate
  • Ethinyl Estradiol; Norgestimate
  • Ethinyl Estradiol; Norgestrel
  • Ethosuximide
  • Ethotoin
  • Etomidate
  • Etravirine
  • Everolimus
  • Exenatide
  • Ezetimibe; Simvastatin
  • Fedratinib
  • Felodipine
  • Fenoprofen
  • Fentanyl
  • Fesoterodine
  • Fexofenadine; Pseudoephedrine
  • Flibanserin
  • Fluconazole
  • Fluoxetine
  • Fluoxetine; Olanzapine
  • Fluphenazine
  • Flurazepam
  • Fluticasone
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • Fluvoxamine
  • food
  • Formoterol
  • Formoterol; Mometasone
  • Fosamprenavir
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Fosphenytoin
  • Fospropofol
  • Fostamatinib
  • Frovatriptan
  • Furosemide
  • Gabapentin
  • Galantamine
  • Gallium Ga 68 Dotatate
  • General anesthetics
  • Givosiran
  • Glasdegib
  • Glimepiride
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glycopyrrolate; Formoterol
  • Granisetron
  • grapefruit juice
  • Green Tea
  • Griseofulvin
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Pseudoephedrine
  • Guanabenz
  • Guanfacine
  • Haloperidol
  • Halothane
  • Hemin
  • Homatropine; Hydrocodone
  • Hydantoins
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Hydroxyprogesterone
  • Hydroxyzine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Idelalisib
  • Ifosfamide
  • Iloperidone
  • Imatinib
  • Imipramine
  • Indacaterol
  • Indacaterol; Glycopyrrolate
  • Indapamide
  • Indinavir
  • Insulin Glargine; Lixisenatide
  • Isavuconazonium
  • Isocarboxazid
  • Isoflurane
  • Isoniazid, INH
  • Isoniazid, INH; Pyrazinamide, PZA; Rifampin
  • Isoniazid, INH; Rifampin
  • Isoproterenol
  • Isradipine
  • Istradefylline
  • Itraconazole
  • Ivabradine
  • Ixabepilone
  • Ketamine
  • Ketoconazole
  • Ketoprofen
  • Lamivudine, 3TC; Zidovudine, ZDV
  • Lamotrigine
  • Lansoprazole
  • Lansoprazole; Naproxen
  • Lanthanum Carbonate
  • Lapatinib
  • Larotrectinib
  • Lasmiditan
  • Lefamulin
  • Lemborexant
  • Lesinurad
  • Lesinurad; Allopurinol
  • Letermovir
  • Leucovorin
  • Levalbuterol
  • Levobupivacaine
  • Levocetirizine
  • Levoleucovorin
  • Levomilnacipran
  • Levorphanol
  • Lidocaine
  • Lidocaine; Prilocaine
  • Linagliptin
  • Linagliptin; Metformin
  • Lincosamides
  • Linezolid
  • Lisdexamfetamine
  • Lithium
  • Lixisenatide
  • Lofexidine
  • Lomitapide
  • Loop diuretics
  • Loperamide
  • Loperamide; Simethicone
  • Lopinavir; Ritonavir
  • Loratadine; Pseudoephedrine
  • Lorazepam
  • Lorlatinib
  • Lovastatin
  • Lovastatin; Niacin
  • Loxapine
  • Lumacaftor; Ivacaftor
  • Lumateperone
  • Lurasidone
  • Magnesium Salicylate
  • Magnesium Salts
  • Mannitol
  • Maprotiline
  • Mebendazole
  • Meclizine
  • Mefloquine
  • Melatonin
  • Meperidine
  • Meperidine; Promethazine
  • Mephobarbital
  • Mepivacaine
  • Mepivacaine; Levonordefrin
  • Meprobamate
  • Mestranol; Norethindrone
  • Metaproterenol
  • Metaxalone
  • Metformin; Repaglinide
  • Methadone
  • Methamphetamine
  • Methazolamide
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methocarbamol
  • Methohexital
  • Methscopolamine
  • Methsuximide
  • Methyclothiazide
  • Methyldopa
  • Methylene Blue
  • Methylphenidate
  • Methylprednisolone
  • Metoclopramide
  • Metolazone
  • Metronidazole
  • Metyrapone
  • Metyrosine
  • Mexiletine
  • Midazolam
  • Midodrine
  • Mifepristone
  • Milnacipran
  • Minocycline
  • Mipomersen
  • Mirabegron
  • Mirtazapine
  • Mitotane
  • Modafinil
  • Molindone
  • Monoamine oxidase inhibitors
  • Morphine
  • Morphine; Naltrexone
  • Nabilone
  • Nafcillin
  • Nalbuphine
  • Naloxone
  • Naltrexone
  • Nanoparticle Albumin-Bound Paclitaxel
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Naratriptan
  • Nefazodone
  • Nelfinavir
  • Neratinib
  • Nesiritide, BNP
  • Netupitant, Fosnetupitant; Palonosetron
  • Nevirapine
  • Niacin; Simvastatin
  • Nicardipine
  • Nifedipine
  • Nilotinib
  • Nimodipine
  • Nintedanib
  • Nisoldipine
  • Nitroglycerin
  • Non-Ionic Contrast Media
  • Norepinephrine
  • Nortriptyline
  • Obeticholic Acid
  • Octreotide
  • Olanzapine
  • Olaparib
  • Olodaterol
  • Ombitasvir; Paritaprevir; Ritonavir
  • Omeprazole
  • Omeprazole; Amoxicillin; Rifabutin
  • Omeprazole; Sodium Bicarbonate
  • Ondansetron
  • Oritavancin
  • Orphenadrine
  • Osilodrostat
  • Oxazepam
  • Oxybutynin
  • Oxycodone
  • Oxymorphone
  • Ozanimod
  • Paclitaxel
  • Palbociclib
  • Paliperidone
  • Palonosetron
  • Panobinostat
  • Papaverine
  • Paroxetine
  • Peginterferon Alfa-2b
  • Pegvisomant
  • Pemigatinib
  • Pemoline
  • Penicillin G Benzathine; Penicillin G Procaine
  • Penicillin G Procaine
  • Pentazocine
  • Pentazocine; Naloxone
  • Pentobarbital
  • Perampanel
  • Perindopril; Amlodipine
  • Perphenazine
  • Perphenazine; Amitriptyline
  • Phendimetrazine
  • Phenelzine
  • Phenobarbital
  • Phenothiazines
  • Phentermine
  • Phentermine; Topiramate
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Phenytoin
  • Pimavanserin
  • Pimozide
  • Pirbuterol
  • Pneumococcal Vaccine, Polyvalent
  • Pomalidomide
  • Posaconazole
  • Potassium-sparing diuretics
  • Pralidoxime
  • Pramipexole
  • Pramlintide
  • Prasugrel
  • Prednisolone
  • Prednisone
  • Pregabalin
  • Prilocaine
  • Prilocaine; Epinephrine
  • Primidone
  • Procarbazine
  • Prochlorperazine
  • Progestins
  • Promethazine
  • Propafenone
  • Propofol
  • Protriptyline
  • Pseudoephedrine
  • Quazepam
  • Quetiapine
  • Quinidine
  • Quinine
  • Rabeprazole
  • Racepinephrine
  • Ramelteon
  • Ranolazine
  • Rasagiline
  • Red Yeast Rice
  • Regadenoson
  • Remifentanil
  • Repaglinide
  • Reserpine
  • Ribociclib
  • Ribociclib; Letrozole
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Rifaximin
  • Rilpivirine
  • Riluzole
  • Rimegepant
  • Risperidone
  • Ritodrine
  • Ritonavir
  • Rizatriptan
  • Roflumilast
  • Rolapitant
  • Romidepsin
  • Ropinirole
  • Ropivacaine
  • Rotigotine
  • Rucaparib
  • Safinamide
  • Salicylates
  • Salmeterol
  • Salsalate
  • Saquinavir
  • Scopolamine
  • Secobarbital
  • Segesterone Acetate; Ethinyl Estradiol
  • Selegiline
  • Selpercatinib
  • Selumetinib
  • Serotonin-Receptor Agonists
  • Serotonin-Receptor Antagonists
  • Sertraline
  • Sevoflurane
  • Sildenafil
  • Simvastatin
  • Simvastatin; Sitagliptin
  • Siponimod
  • Sirolimus
  • Skeletal Muscle Relaxants
  • Sodium Bicarbonate
  • Sodium Oxybate
  • Solifenacin
  • Solriamfetol
  • Spironolactone
  • St. John’s Wort, Hypericum perforatum
  • Streptogramins
  • Sufentanil
  • Sulfinpyrazone
  • Sumatriptan
  • Sunitinib
  • Suvorexant
  • Tacrolimus
  • Tapentadol
  • Tasimelteon
  • Tazemetostat
  • Telaprevir
  • Telithromycin
  • Telotristat Ethyl
  • Temazepam
  • Terbinafine
  • Terbutaline
  • Teriflunomide
  • Tetrabenazine
  • Tetracaine
  • Thalidomide
  • Theophylline, Aminophylline
  • Thiabendazole
  • Thiazide diuretics
  • Thiopental
  • Thioridazine
  • Thiothixene
  • Thyroid hormones
  • Ticagrelor
  • Tiotropium; Olodaterol
  • Tipranavir
  • Tizanidine
  • tobacco
  • Tolcapone
  • Tolterodine
  • Topiramate
  • Torsemide
  • Tramadol
  • Trandolapril; Verapamil
  • Tranylcypromine
  • Trazodone
  • Tretinoin, ATRA
  • Triamcinolone
  • Triamterene
  • Triazolam
  • Tricyclic antidepressants
  • Trifluoperazine
  • Trimethobenzamide
  • Trimetrexate
  • Trimipramine
  • Triprolidine
  • Trospium
  • Tucatinib
  • Ubrogepant
  • Ulipristal
  • Umeclidinium; Vilanterol
  • Valbenazine
  • Valerian, Valeriana officinalis
  • Valproic Acid, Divalproex Sodium
  • Vemurafenib
  • Venlafaxine
  • Verapamil
  • Vigabatrin
  • Vilazodone
  • Vincristine
  • Vincristine Liposomal
  • Vorapaxar
  • Voriconazole
  • Vortioxetine
  • Voxelotor
  • Warfarin
  • Yohimbine
  • Zaleplon
  • Zanubrutinib
  • Ziconotide
  • Zidovudine, ZDV
  • Zileuton
  • Ziprasidone
  • Zolmitriptan
  • Zolpidem
  • Zonisamide
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