What is Regadenoson
Regadenoson is an A2A adenosine receptor agonist that acts as a coronary vasodilator and is used as a pharmacologic stress agent in radionuclide myocardial perfusion imaging.
Regadenoson can be used as an alternative to adenosine for diagnosing coronary artery disease.
Brand Name
Lexiscan
Indications
- coronary artery disease diagnosis
For use in radionuclide myocardial perfusion imaging for coronary artery disease diagnosis in patients unable to undergo adequate exercise stress
Side Effects
- abdominal pain
- anaphylactic shock
- anaphylactoid reactions
- angina
- angioedema
- asystole
- atrial fibrillation
- atrial flutter
- AV block
- back pain
- bradycardia
- bronchospasm
- cardiac arrest
- chest pain (unspecified)
- diarrhea
- dizziness
- dysgeusia
- dyspnea
- fecal incontinence
- flushing
- headache
- hypertension
- hypotension
- intracranial bleeding
- musculoskeletal pain
- myalgia
- myocardial infarction
- nausea
- premature atrial contractions (PACs)
- premature ventricular contractions (PVCs)
- QT prolongation
- rash
- respiratory arrest
- seizures
- sinus tachycardia
- stroke
- syncope
- tachypnea
- tremor
- urticaria
- vomiting
- wheezing
Monitoring Parameters
- ECG
Contraindications
- angina
- asthma
- autonomic neuropathy
- AV block
- bradycardia
- breast-feeding
- cardiac arrest
- cardiac disease
- chronic obstructive pulmonary disease (COPD)
- geriatric
- hypotension
- hypovolemia
- myocardial infarction
- pericardial effusion
- pericarditis
- pregnancy
- pulmonary disease
- pulmonary edema
- respiratory arrest
- seizures
- sick sinus syndrome
- valvular heart disease
- ventricular fibrillation
Interactions
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Dipyridamole
- Caffeine
- Caffeine; Ergotamine
- Digoxin
- Dipyridamole
- Green Tea
- Nicotine
- Theophylline, Aminophylline
- tobacco
- Trandolapril; Verapamil
- Verapamil
