Cefoperazone Brand Name– Cefobid What is Cefoperazone Cefoperazone is a parenteral third-generation cephalosporin. It differs structurally from other cephalosporins by the addition of a piperazine side chain and a methyltetrazolethiol side chain. The piperazine side chain imparts improved antipseudomonal activity, whereas the methyltetrazolethiol side chain is believed to be responsible for the hypoprothrombinemia associated with …
Cefixime Brand Name– Suprax What is Cefixime Cefixime is a third-generation cephalosporin available in an oral formulation. In general, third-generation cephalosporins are more active against gram-negative species than are the earlier generations of cephalosporins. Like ceftriaxone and cefotaxime, cefixime has enhanced antibacterial activity and increased stability against many of the beta-lactamases. Cefixime is commonly used …
Cefiderocol Brand Name– FETROJA What is Cefiderocol Cefiderocol is a parenteral siderophore cephalosporin antibacterial indicated for the treatment of complicated urinary tract infections (cUTIs), including pyelonephritis, in adults who have limited or no treatment options. Approval of cefiderocol for this indication is based on limited clinical safety and efficacy data. In a multinational, randomized, open-label …
Cefepime Brand Name– Maxipime What is Cefepime Cefepime is a parenteral cephalosporin with pharmacokinetics and spectrum of activity similar to ceftazidime, a ‘third-generation’ cephalosporin. Because cefepime may be active against some organisms resistant to ceftazidime, some consider cefepime a ‘fourth-generation’ cephalosporin. Cefepime is comparable to ceftazidime in its coverage of Pseudomonas aeruginosa, and it may be …
Cefditoren Brand Name– Spectracef What is Cefditoren Cefditoren pivoxil (also known as ME-1206) is an oral prodrug for cefditoren. Cefditoren is a semi-synthetic, broad-spectrum, third generation cephalosporin that is a very potent oral beta-lactam antibiotic. It is active against both beta-lactamase negative and positive Haemophilus influenzae, but is not active against Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Acinetobacter, and other non-fermentors. …
Cefdinir Brand Name– Omnicef What is Cefdinir Cefdinir (FK482, CI—983) is an oral extended-spectrum, semisynthetic, cephalosporin. It is generally classified as a third generation cephalosporin with activity similar to cefotaxime and cefixime. In a comparison to cefixime, cefpodoxime, cefaclor, and cephalexin in vitro, cefdinir is more active against oxacillin-sensitive Staphylcoccus aureus and coagulase-negative staphylococci, Streptococcus pneumoniae, S. pyogens, Escherichia …
Cefazolin Brand Names Ancef | Kefzol What is Cefazolin Cefazolin is a parenteral first-generation cephalosporin with greater activity against gram-positive bacteria than most other cephalosporins. Similar to other first-generation cephalosporins, cefazolin is active against gram-positive aerobic cocci, but has limited activity against gram-negative bacteria. Cefazolin has a longer half-life than other first-generation cephalosporins and, since fewer …