Drugs

Celecoxib

Celecoxib Brand Names Celebrex | ELYXYB What is Celecoxib Celecoxib is an oral nonsteroidal anti-inflammatory drug (NSAID), a selective cyclooxygenase-2 (COX-2) inhibitor, indicated for osteoarthritis, rheumatoid arthritis, juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, primary dysmenorrhea, acute pain, and migraine with or without aura. All NSAIDs, including naproxen, cause serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, …

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Cefuroxime

Cefuroxime Brand Names Alti-Cefuroxime | Ceftin | Kefurox | Zinacef What is Cefuroxime Cefuroxime is an oral (cefuroxime axetil) and parenteral (cefuroxime sodium) second-generation cephalosporin. Although the dosage forms differ, the bacterial spectrum and mechanism of action are the same. Similar to other second-generation cephalosporins, cefuroxime is more active against gram-negative bacteria than the first-generation cephalosporins, but not …

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Ceftriaxone

Ceftriaxone Brand Name– Ceftrisol Plus | Rocephin What is Ceftriaxone Ceftriaxone is a parenteral third-generation cephalosporin. Similar to other third-generation cephalosporins, ceftriaxone possesses significant activity against serious gram-negative organisms and also penetrates the CSF in concentrations that make it useful in the treatment of meningitis. Ceftriaxone has the longest half-life of all cephalosporins, allowing for once-daily …

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Ceftolozane Tazobactam

Ceftolozane Tazobactam Brand Name– ZERBAXA What is Ceftolozane Tazobactam Ceftolozane tazobactam is a combination intravenous anti-infective, including ceftolozane, a cephalosporin antibacterial, and tazobactam, a beta-lactamase inhibitor, indicated for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, hospital-acquired pneumonia (HAP), and ventilator-associated pneumonia (VAP) in adults. Decreased efficacy has been observed with ceftolozane; tazobactam …

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Ceftizoxime

Ceftizoxime Brand Name What is Ceftizoxime Ceftizoxime is a parenteral third-generation cephalosporin antibiotic. Its spectrum includes some gram-positive organisms but has predominantly gram-negative coverage. Ceftizoxime is indicated for the treatment of upper and lower respiratory tract infections, sexually transmitted diseases, intra-abdominal infections, septicemia, bone and joint infections, meningitis caused by Haemophilus influenzae, urinary tract infections, and …

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Ceftibuten

Ceftibuten Brand Name– Cedax What is Ceftibuten Ceftibuten is an oral, third-generation cephalosporin. Ceftibuten is more beta-lactamase stable compared to other beta-lactamase stable cephalosporins; however, ceftibuten is inactivated by type I beta-lactamase produced by Enterobacter, Pseudomonas, and Serratia species. In addition, resistance occurs in over 15% of strains of Citrobacter freundii and Morganella morganii. Although ceftibuten possesses activity against a variety of …

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Ceftazidime Avibactam

Ceftazidime Avibactam Brand Name– AVYCAZ What is Ceftazidime Avibactam Ceftazidime avibactam is a combination product consisting of a third-generation cephalosporin and a beta-lactamase inhibitor. The drug is indicated for the treatment of complicated intra-abdominal infections (when used in combination with metronidazole) and complicated urinary tract infections in adult and pediatric patients 3 months and older. …

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