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What is Zanamivir
Zanamivir is a neuraminidase inhibitor antiviral agent that is most commonly administered via oral inhalation and indicated for the treatment of uncomplicated influenza A and B infection in patients 7 years and older and for seasonal influenza prophylaxis in patients 5 years and older.
Brand Name
Relenza
Indications & Dosage
- avian influenza A (H5N1) virus
- avian influenza A (H7N9) virus
- avian influenza A virus infection
- avian influenza prophylaxis
- influenza A virus
- influenza A virus infection
- influenza B virus
- influenza B virus infection
- seasonal influenza prophylaxis
Side Effects
- abdominal pain
- agitation
- anaphylactoid reactions
- angioedema
- anorexia
- anxiety
- appetite stimulation
- arrhythmia exacerbation
- arthralgia
- bronchospasm
- chills
- confusion
- cough
- delirium
- diarrhea
- dizziness
- dyspnea
- elevated hepatic enzymes
- emotional lability
- erythema multiforme
- fatigue
- fever
- hallucinations
- headache
- infection
- laryngeal edema
- lymphopenia
- malaise
- musculoskeletal pain
- myalgia
- nausea
- neutropenia
- nightmares
- psychosis
- rash
- seizures
- sinusitis
- Stevens-Johnson syndrome
- syncope
- toxic epidermal necrolysis
- urticaria
- vomiting
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- administration via nebulizer
- angioedema
- asthma
- breast-feeding
- bronchitis
- cardiac disease
- children
- chronic obstructive pulmonary disease (COPD)
- emphysema
- geriatric
- milk protein hypersensitivity
- pregnancy
- pulmonary disease
- renal failure
- renal impairment
- Reye’s syndrome
- serious rash
- vaccination
- viral infection
Interactions
- Intranasal Influenza Vaccine