Uridine Triacetate

What is Uridine Triacetate

Uridine triacetate (Xuriden, Vistogard) is an orally administered pyrimidine analog.

Xuriden is indicated as uridine replacement therapy in patients with hereditary orotic aciduria, a rare congenital autosomal recessive disorder of pyrimidine metabolism. 

Brand Names

  • VISTOGARD
  • Xuriden

Indications

  • capecitabine overdose
  • capecitabine toxicity
  • fluorouracil overdose
  • fluorouracil toxicity
  • hereditary orotic aciduria

Side Effects

  • diarrhea
  • nausea
  • vomiting

Monitoring Parameters

  • CBC
  • red blood cell count (RBC)

Contraindications

  • breast-feeding
  • pregnancy

Interactions

  • Digoxin