Terazosin

What is Terazosin

Terazosin is an alpha-adrenergic blocking agent used in the treatment of hypertension and benign prostatic hypertrophy (BPH).

It is classified as a quinazoline and is similar to doxazosin and prazosin.

The duration of action of terazosin is longer than that of prazosin but shorter than that of doxazosin. In a head-to-head comparison with finasteride, terazosin achieved superior results in the management of BPH.

Terazosin was FDA-approved for hypertension in August 1987 and for BPH in 1993. The patent expired in 1997.

Brand Name

Hytrin

Side Effects

  1. abdominal pain
  2. amblyopia
  3. anaphylactoid reactions
  4. anxiety
  5. arthralgia
  6. arthropathy
  7. asthenia
  8. atrial fibrillation
  9. back pain
  10. blurred vision
  11. chest pain (unspecified)
  12. conjunctivitis
  13. constipation
  14. cough
  15. depression
  16. diarrhea
  17. dizziness
  18. drowsiness
  19. dyspepsia
  20. dyspnea
  21. edema
  22. epistaxis
  23. fever
  24. flatulence
  25. floppy iris syndrome
  26. gout
  27. headache
  28. hyperhidrosis
  29. impotence (erectile dysfunction)
  30. increased urinary frequency
  31. infection
  32. influenza
  33. insomnia
  34. libido decrease
  35. myalgia
  36. nasal congestion
  37. nausea
  38. orthostatic hypotension
  39. palpitations
  40. paresthesias
  41. peripheral edema
  42. peripheral vasodilation
  43. pharyngitis
  44. priapism
  45. pruritus
  46. rash
  47. rhinitis
  48. sinus tachycardia
  49. sinusitis
  50. syncope
  51. thrombocytopenia
  52. tinnitus
  53. urinary incontinence
  54. vertigo
  55. visual impairment
  56. vomiting
  57. weight gain
  58. xerostomia

Monitoring Parameters

  • blood pressure

Contraindications

  • angina
  • breast-feeding
  • geriatric
  • ocular surgery
  • orthostatic hypotension
  • pregnancy
  • priapism
  • syncope

Interactions

  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Pseudoephedrine
  • Acrivastine; Pseudoephedrine
  • Aldesleukin, IL-2
  • Alemtuzumab
  • Alfuzosin
  • Alprostadil
  • Amifostine
  • Amobarbital
  • Amphetamines
  • Amyl Nitrite
  • Apomorphine
  • Apraclonidine
  • Aripiprazole
  • Articaine; Epinephrine
  • Asenapine
  • Avanafil
  • Baclofen
  • Beta-blockers
  • Bortezomib
  • Bosentan
  • Brexpiprazole
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Cabergoline
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cariprazine
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Co-Enzyme Q10, Ubiquinone
  • Codeine; Phenylephrine; Promethazine
  • Conivaptan
  • Desloratadine; Pseudoephedrine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexmethylphenidate
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Dextromethorphan; Quinidine
  • Diazoxide
  • Diethylpropion
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Phenylephrine
  • Dobutamine
  • Dopamine
  • Drospirenone; Ethinyl Estradiol
  • Drospirenone; Ethinyl Estradiol; Levomefolate
  • Duloxetine
  • Dutasteride; Tamsulosin
  • Enflurane
  • Ephedrine
  • Epinephrine
  • Epoprostenol
  • Estradiol
  • Estradiol Cypionate; Medroxyprogesterone
  • Ethanol
  • Ethinyl Estradiol
  • Ethinyl Estradiol; Desogestrel
  • Ethinyl Estradiol; Ethynodiol Diacetate
  • Ethinyl Estradiol; Etonogestrel
  • Ethinyl Estradiol; Levonorgestrel
  • Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
  • Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
  • Ethinyl Estradiol; Norelgestromin
  • Ethinyl Estradiol; Norethindrone
  • Ethinyl Estradiol; Norethindrone Acetate
  • Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
  • Ethinyl Estradiol; Norethindrone; Ferrous fumarate
  • Ethinyl Estradiol; Norgestimate
  • Ethinyl Estradiol; Norgestrel
  • Etomidate
  • Fexofenadine; Pseudoephedrine
  • Finasteride
  • Fluoxetine; Olanzapine
  • Fospropofol
  • General anesthetics
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Pseudoephedrine
  • Haloperidol
  • Halothane
  • Hydralazine; Isosorbide Dinitrate, ISDN
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Ibuprofen; Pseudoephedrine
  • Iloperidone
  • Iloprost
  • Isocarboxazid
  • Isoflurane
  • Isoproterenol
  • Isosorbide Dinitrate, ISDN
  • Isosorbide Mononitrate
  • Ketamine
  • Lofexidine
  • Loratadine; Pseudoephedrine
  • Lovastatin; Niacin
  • Lurasidone
  • Mestranol; Norethindrone
  • Methohexital
  • Methylphenidate
  • Midodrine
  • Milrinone
  • Naproxen; Pseudoephedrine
  • Nesiritide, BNP
  • Niacin, Niacinamide
  • Niacin; Simvastatin
  • Nicotine
  • Nitrates
  • Nitroglycerin
  • Nitroprusside
  • Nonsteroidal antiinflammatory drugs
  • Norepinephrine
  • Olanzapine
  • Oxymetazoline
  • Paliperidone
  • Pentoxifylline
  • Phendimetrazine
  • Phenelzine
  • Phentermine
  • Phentermine; Topiramate
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Prilocaine; Epinephrine
  • Procainamide
  • Procaine
  • Propofol
  • Pseudoephedrine
  • Quinidine
  • Rasagiline
  • Risperidone
  • Ritodrine
  • Segesterone Acetate; Ethinyl Estradiol
  • Selegiline
  • Sevoflurane
  • Sildenafil
  • Silodosin
  • Tadalafil
  • Tamsulosin
  • Tetrabenazine
  • Tetracaine
  • Thalidomide
  • Thiopental
  • Thiothixene
  • Tizanidine
  • Trandolapril; Verapamil
  • Tranylcypromine
  • Trazodone
  • Vardenafil
  • Verapamil
  • Yohimbine
  • Ziprasidone
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