What is Sodium Hyaluronate and Hyaluronic Acid
Sodium hyaluronate is the high molecular weight fractions of purified natural sodium hyaluronic acid.
It is used clinically as an intra-articular, intradermal, and ophthalmic viscoelastic agent and applied topically to protect against abrasion, friction, and desiccation
Indications & Dosage
- atopic dermatitis
- burns
- contact dermatitis
- decubitus ulcer
- dermatitis
- diabetic foot ulcer
- facial wrinkles
- ocular surgery
- ophthalmic surgery
- osteoarthritis
- skin abrasion
- wound management
Side Effects
- abdominal pain
- anaphylactoid reactions
- angioedema
- anxiety
- arrhythmia exacerbation
- arthralgia
- arthropathy
- asthenia
- back pain
- chills
- corneal edema
- corneal opacification
- cystitis
- depression
- diarrhea
- dizziness
- dysgeusia
- dyspepsia
- ecchymosis
- edema
- erythema
- fatigue
- fever
- headache
- infection
- influenza
- injection site reaction
- iritis
- leukocytosis
- metallic taste
- muscle cramps
- musculoskeletal pain
- myalgia
- nausea
- ocular hypertension
- ocular infection
- ocular pain
- paresthesias
- peptic ulcer
- peripheral edema
- pharyngitis
- phlebitis
- pruritus
- purpura
- rash
- rhinitis
- sinusitis
- synovitis
- thrombocytopenia
- urticaria
- vomiting
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- anticoagulant therapy
- aphakia
- breast-feeding
- children
- coagulopathy
- diabetes mellitus
- egg hypersensitivity
- glaucoma
- hemophilia
- infants
- infection
- intraarterial administration
- intravenous administration
- neonates
- pregnancy
- skin disease
- thrombocytopenia
Interactions
- Abciximab
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Alteplase
- Aminosalicylate sodium, Aminosalicylic acid
- Amlodipine; Celecoxib
- Anagrelide
- Antithrombin III
- Ardeparin
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Celecoxib
- Choline Salicylate; Magnesium Salicylate
- Cilostazol
- Clopidogrel
- Cranberry, Vaccinium macrocarpon Ait.
- Dalteparin
- Danaparoid
- Diclofenac
- Diclofenac; Misoprostol
- Diflunisal
- Diphenhydramine; Ibuprofen
- Diphenhydramine; Naproxen
- Dipyridamole
- Enoxaparin
- Eptifibatide
- Esomeprazole; Naproxen
- Etodolac
- Famotidine; Ibuprofen
- Fenoprofen
- Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
- Flurbiprofen
- Fondaparinux
- Heparin
- Hydrocodone; Ibuprofen
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibuprofen
- Ibuprofen; Oxycodone
- Ibuprofen; Pseudoephedrine
- Indomethacin
- Ketoprofen
- Ketorolac
- Lansoprazole; Naproxen
- Low Molecular Weight Heparins
- Magnesium Salicylate
- Meclofenamate Sodium
- Mefenamic Acid
- Meloxicam
- Nabumetone
- Naproxen
- Naproxen; Pseudoephedrine
- Naproxen; Sumatriptan
- Nonsteroidal antiinflammatory drugs
- Oxaprozin
- Pentosan
- Piroxicam
- Platelet Inhibitors
- Prasugrel
- Reteplase, r-PA
- Rofecoxib
- Salicylates
- Salsalate
- St. John’s Wort, Hypericum perforatum
- Streptokinase
- Sulindac
- Tenecteplase
- Thrombolytic Agents
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tirofiban
- Tolmetin
- Urokinase
- Valdecoxib
- Vitamin E
- Vitamin E
- Vorapaxar
- Warfarin
