Racepinephrine

What is Racepinephrine

Racepinephrine, a racemic mixture of epinephrine, is an inhalation sympathomimetic bronchodilator agent.

Racepinephrine is about one-half as active as epinephrine and is used for the temporary relief of shortness of breath, chest tightness, and wheezing due to bronchial asthma in adults and children 4 years of age and older.

Brand Name

  • Asthmanefrin
  • S-2

Indications

  • acute bronchospasm
  • asthma

For the temporary relief of mild symptoms of intermittent asthma such as mild acute bronchospasm (wheezing), tightness of the chest, and mild shortness of breath

Side Effects

  1. angina
  2. anxiety
  3. arrhythmia exacerbation
  4. chest pain (unspecified)
  5. dizziness
  6. headache
  7. hemoptysis
  8. hyperglycemia
  9. hypertension
  10. insomnia
  11. intracranial bleeding
  12. myocardial infarction
  13. nausea
  14. pallor
  15. palpitations
  16. peripheral vasoconstriction
  17. restlessness
  18. seizures
  19. sinus tachycardia
  20. stroke
  21. tremor
  22. vomiting
  23. weakness

Monitoring Parameters

  • pulmonary function tests (PFTs)

Contraindications

  • angina
  • breast-feeding
  • cardiac disease
  • children
  • closed-angle glaucoma
  • diabetes mellitus
  • hypertension
  • hyperthyroidism
  • infants
  • labor
  • MAOI therapy
  • myocardial infarction
  • neonates
  • obstetric delivery
  • pheochromocytoma
  • pregnancy
  • prostatic hypertrophy
  • seizures
  • stroke
  • tachycardia
  • thyroid disease

Interactions

  • Acarbose
  • Acebutolol
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Pseudoephedrine
  • Aclidinium; Formoterol
  • Acrivastine; Pseudoephedrine
  • Albiglutide
  • Albuterol
  • Albuterol; Ipratropium
  • Alogliptin; Pioglitazone
  • Alpha-glucosidase Inhibitors
  • Amitriptyline
  • Amitriptyline; Chlordiazepoxide
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamines
  • Arformoterol
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Atenolol
  • Atenolol; Chlorthalidone
  • Atomoxetine
  • Bendroflumethiazide; Nadolol
  • Benzphetamine
  • Beta-blockers
  • Betaxolol
  • Bethanechol
  • Bisoprolol
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Bosentan
  • Bretylium
  • Brimonidine; Timolol
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide; Formoterol
  • Caffeine
  • Caffeine; Ergotamine
  • Canagliflozin
  • Canagliflozin; Metformin
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Carteolol
  • Carvedilol
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Clomipramine
  • Cocaine
  • Codeine; Phenylephrine; Promethazine
  • Colchicine
  • Colchicine; Probenecid
  • Dapagliflozin
  • Dapagliflozin; Metformin
  • Dapagliflozin; Saxagliptin
  • Desipramine
  • Desloratadine; Pseudoephedrine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dextroamphetamine
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Digitoxin
  • Digoxin
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Dipeptidyl Peptidase-4 Inhibitors
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Phenylephrine
  • Dopamine
  • Dorzolamide; Timolol
  • Doxepin
  • Dronabinol
  • Droxidopa
  • Dulaglutide
  • Dyphylline
  • Dyphylline; Guaifenesin
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Entacapone
  • Ephedrine
  • Epoprostenol
  • Ertugliflozin
  • Ertugliflozin; Metformin
  • Ertugliflozin; Sitagliptin
  • Esmolol
  • Exenatide
  • Fexofenadine; Pseudoephedrine
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • Formoterol
  • Formoterol; Mometasone
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glycopyrrolate; Formoterol
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Pseudoephedrine
  • Guanabenz
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Ibuprofen; Pseudoephedrine
  • Iloprost
  • Imipramine
  • Incretin Mimetics
  • Indacaterol
  • Indacaterol; Glycopyrrolate
  • Insulin Degludec; Liraglutide
  • Insulin Glargine; Lixisenatide
  • Insulins
  • Iobenguane I 131
  • Isocarboxazid
  • Labetalol
  • Levalbuterol
  • Levobetaxolol
  • Levobunolol
  • Levothyroxine
  • Levothyroxine; Liothyronine (Porcine)
  • Levothyroxine; Liothyronine (Synthetic)
  • Linezolid
  • Liothyronine
  • Liraglutide
  • Lisdexamfetamine
  • Lixisenatide
  • Loratadine; Pseudoephedrine
  • Macitentan
  • Maprotiline
  • Mecamylamine
  • Meglitinides
  • Metaproterenol
  • Metformin; Pioglitazone
  • Metformin; Rosiglitazone
  • Methamphetamine
  • Metoprolol
  • Midodrine
  • Miglitol
  • Monoamine oxidase inhibitors
  • Nabilone
  • Nadolol
  • Naproxen; Pseudoephedrine
  • Nebivolol
  • Nebivolol; Valsartan
  • Nitrates
  • Norepinephrine
  • Nortriptyline
  • Olodaterol
  • Ozanimod
  • Penbutolol
  • Perphenazine; Amitriptyline
  • Phenelzine
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Pindolol
  • Pioglitazone
  • Pirbuterol
  • Pramlintide
  • Procarbazine
  • Propranolol
  • Protriptyline
  • Pseudoephedrine
  • Rasagiline
  • Riociguat
  • Rosiglitazone
  • Safinamide
  • Salmeterol
  • Selegiline
  • Selexipag
  • Semaglutide
  • SGLT2 Inhibitors
  • Sotalol
  • Sulfonylureas
  • Terbutaline
  • Theophylline, Aminophylline
  • Thiazolidinediones
  • Thyroid hormones
  • Timolol
  • Tiotropium; Olodaterol
  • Tolcapone
  • Tranylcypromine
  • Treprostinil
  • Tricyclic antidepressants
  • Trimipramine
  • Umeclidinium; Vilanterol
  • Vasodilators
  • Vasopressors
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