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Chloroprocaine Brand Names
CLOROTEKAL | Nesacaine | Nesacaine MPF
What is Chloroprocaine
Chloroprocaine is a short-acting local anesthetic of the ester type, similar in structure to procaine.
Chloroprocaine is indicated for infiltration anesthesia and peripheral, sympathetic, epidural, caudal, subarachnoid, and intravenous regional (Bier’s method) blocks.
Chloroprocaine is not effective as a topical anesthetic.
Indications
- brachial plexus block
- caudal anesthesia
- cervical nerve block
- epidural anesthesia
- infiltration anesthesia
- infraorbital nerve block
- intercostal nerve block
- interdigital block
- local anesthesia
- lumbar sympathetic block
- mandibular nerve block
- maxillary nerve block
- nerve block anesthesia
- obstetric anesthesia
- occipital nerve block
- ophthalmic anesthesia
- paracervical block
- paravertebral block
- pudendal nerve block
- regional anesthesia
- sciatic nerve block
- spinal anesthesia
- stellate ganglion block
- ulnar nerve block
Side Effects
- akathisia
- anaphylactoid reactions
- angina
- angioedema
- anxiety
- apnea
- arachnoiditis
- arrhythmia exacerbation
- atrial fibrillation
- AV block
- back pain
- blurred vision
- bradycardia
- cardiac arrest
- chondrolysis
- coma
- confusion
- diaphoresis
- diplopia
- dizziness
- drowsiness
- dysesthesia
- dyspnea
- erythema
- erythema multiforme
- fetal acidosis
- fetal bradycardia
- fever
- headache
- hot flashes
- hyperglycemia
- hypertension
- hypoesthesia
- hypotension
- hypotonia
- injection site reaction
- laryngeal edema
- malaise
- methemoglobinemia
- muscle paralysis
- myoclonia
- nausea
- neonatal depression
- palpitations
- paresthesias
- peripheral neuropathy
- peripheral vasodilation
- photophobia
- PR prolongation
- pruritus
- QT prolongation
- rash
- respiratory arrest
- respiratory depression
- restlessness
- seizures
- shivering
- sinus tachycardia
- sneezing
- syncope
- tinnitus
- tremor
- urinary incontinence
- urticaria
- visual impairment
- vomiting
- weakness
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- AV block
- breast-feeding
- cardiac disease
- coagulopathy
- dehydration
- eclampsia
- epidural administration
- ester local anesthetic hypersensitivity
- fetal distress
- fetal prematurity
- G6PD deficiency
- geriatric
- head and neck anesthesia
- hepatic disease
- hypertension
- hypotension
- hypovolemia
- infants
- infection
- intraarterial administration
- intrathecal administration
- intravenous administration
- labor
- methemoglobinemia
- myasthenia gravis
- neonates
- neurological disease
- obstetric delivery
- ocular surgery
- para-aminobenzoic acid, PABA hypersensitivity
- paraben hypersensitivity
- paracervical nerve block
- pregnancy
- pseudocholinesterase deficiency
- pudendal nerve block
- pulmonary disease
- renal failure
- renal impairment
- requires an experienced clinician
- sepsis
- shock
Interactions
- Acebutolol
- Acetaminophen
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Diphenhydramine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Pseudoephedrine
- Acetaminophen; Tramadol
- Alfentanil
- Alfuzosin
- Aliskiren; Amlodipine
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Ambenonium Chloride
- Amiloride
- Amiloride; Hydrochlorothiazide, HCTZ
- Aminosalicylate sodium, Aminosalicylic acid
- Amlodipine
- Amlodipine; Atorvastatin
- Amlodipine; Benazepril
- Amlodipine; Celecoxib
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Amlodipine; Olmesartan
- Amlodipine; Telmisartan
- Amlodipine; Valsartan
- Angiotensin II receptor antagonists
- Angiotensin-converting enzyme inhibitors
- Articaine; Epinephrine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Oxycodone
- Atenolol
- Atenolol; Chlorthalidone
- Atracurium
- Atropine; Edrophonium
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Bendroflumethiazide; Nadolol
- Benzhydrocodone; Acetaminophen
- Benzocaine
- Benzocaine; Butamben; Tetracaine
- Benzonatate
- Beta-adrenergic blockers
- Betaxolol
- Bisoprolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Brimonidine; Timolol
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Bupivacaine
- Bupivacaine Liposomal
- Bupivacaine; Lidocaine
- Caffeine; Ergotamine
- Calcium-channel blockers
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carteolol
- Carvedilol
- Central-acting adrenergic agents
- Chloroquine
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Cholinesterase inhibitors
- Cisatracurium
- Clevidipine
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- Cyclophosphamide
- Dapsone
- Daratumumab; Hyaluronidase
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Dihydroergotamine
- Diltiazem
- Diphenhydramine; Hydrocodone; Phenylephrine
- Donepezil
- Donepezil; Memantine
- Dorzolamide; Timolol
- Doxacurium
- Edrophonium
- Enalapril; Felodipine
- Enflurane
- Eplerenone
- Ergoloid Mesylates
- Ergonovine
- Ergot alkaloids
- Ergotamine
- Erythromycin; Sulfisoxazole
- Esmolol
- Etomidate
- Felodipine
- Fentanyl
- Flutamide
- Fosphenytoin
- Fospropofol
- Galantamine
- General anesthetics
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Halothane
- Homatropine; Hydrocodone
- Hyaluronidase
- Hyaluronidase, Recombinant; Immune Globulin
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydromorphone
- Hydroxyurea
- Ibuprofen; Oxycodone
- Ifosfamide
- Iloprost
- Isoflurane
- Isradipine
- Ketamine
- Labetalol
- Levobetaxolol
- Levobunolol
- Levorphanol
- Lidocaine
- Loop diuretics
- Mecamylamine
- Meperidine
- Meperidine; Promethazine
- Mepivacaine
- Mepivacaine; Levonordefrin
- Methohexital
- Methylergonovine
- Methysergide
- Metoclopramide
- Metoprolol
- Minocycline
- Mivacurium
- Monoamine oxidase inhibitors
- Nadolol
- Nebivolol
- Nebivolol; Valsartan
- Neostigmine
- Neuromuscular blockers
- Nicardipine
- Nifedipine
- Nimodipine
- Nisoldipine
- Nitrates
- Nitrofurantoin
- Oxycodone
- Oxymorphone
- Pancuronium
- Penbutolol
- Pergolide
- Perindopril; Amlodipine
- Phenobarbital
- Phenytoin
- Physostigmine
- Pindolol
- Potassium-sparing diuretics
- Prilocaine
- Prilocaine; Epinephrine
- Primaquine
- Primidone
- Procarbazine
- Propofol
- Propoxyphene
- Propranolol
- Pyridostigmine
- Pyrimethamine; Sulfadoxine
- Quinine
- Rapacuronium
- Rasburicase
- Remifentanil
- Reserpine
- Rituximab; Hyaluronidase
- Rivastigmine
- Rocuronium
- Ropivacaine
- Sevoflurane
- Sparfloxacin
- Spironolactone
- Succinylcholine
- Sufentanil
- Sulfadiazine
- Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
- Sulfasalazine
- Sulfisoxazole
- Sulfonamides
- Tacrine
- Tetracaine
- Thiazide diuretics
- Thiopental
- Timolol
- Trandolapril; Verapamil
- Trastuzumab; Hyaluronidase
- Treprostinil
- Triamterene
- Tubocurarine
- Valproic Acid, Divalproex Sodium
- Vasodilators
- Vecuronium
- Verapamil
