Brompheniramine Dextromethorphan Guaifenesin Brand Name– Tusnel
What is Brompheniramine Dextromethorphan Guaifenesin
Brompheniramine dextromethorphan guaifenesin are used together in oral preparations to relieve symptoms associated with allergic rhinitis, the common cold or other minor throat or bronchial irritants.
These symptoms include cough, rhinorrhea, sneezing, and watery eyes. Brompheniramine is a first-generation sedating antihistamine (H1-blocker) of the propylamine class. It dries the nasal and sinus passages secondary to its anticholinergic activity.
Dextromethorphan is a centrally acting cough suppressant.
Guaifenesin loosens and thins phlegm and bronchial secretions to ease expectoration.
Although guaifenesin may be used as an expectorant in both productive and non-productive coughs, it is especially useful in the treatment of dry, non-productive coughs which tend to injure the respiratory mucous membranes.
Indications
- allergic rhinitis
- common cold
- cough
- rhinorrhea
- sneezing
For the relief of cough, rhinorrhea, sneezing, and watery eyes due to allergic rhinitis, the common cold, or other inhaled irritants
Side Effects
- abdominal pain
- anorexia
- blurred vision
- confusion
- constipation
- delirium
- diarrhea
- diplopia
- dizziness
- drowsiness
- dysarthria
- dyskinesia
- dyspepsia
- dysuria
- euphoria
- excitability
- hallucinations
- hypertension
- hypotension
- impotence (erectile dysfunction)
- insomnia
- irritability
- lethargy
- nausea
- palpitations
- rash
- respiratory depression
- restlessness
- seizures
- serotonin syndrome
- sinus tachycardia
- tinnitus
- tremor
- urinary retention
- urticaria
- vertigo
- visual impairment
- vomiting
- weakness
- xerophthalmia
- xerostomia
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- anticholinergic medications
- asthma
- bladder obstruction
- breast-feeding
- bronchitis
- cardiac disease
- children
- chronic obstructive pulmonary disease (COPD)
- closed-angle glaucoma
- contact lenses
- driving or operating machinery
- emphysema
- geriatric
- GI obstruction
- hepatic disease
- hypertension
- hyperthyroidism
- ileus
- increased intraocular pressure
- infants
- MAOI therapy
- neonates
- pregnancy
- prostatic hypertrophy
- seizure disorder
- seizures
- status asthmaticus
- tobacco smoking
- urinary retention
Interactions
- Abiraterone
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Codeine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Tramadol
- Alfentanil
- Alosetron
- Amantadine
- Ambenonium Chloride
- Amiodarone
- Amlodipine; Celecoxib
- Amobarbital
- Amoxapine
- Amphetamine
- Amphetamine; Dextroamphetamine
- Amphetamine; Dextroamphetamine Salts
- Anticholinergics
- Apomorphine
- Aripiprazole
- Artemether; Lumefantrine
- Asenapine
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Oxycodone
- Atazanavir; Cobicistat
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Azelastine
- Azelastine; Fluticasone
- Baclofen
- Barbiturates
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benzhydrocodone; Acetaminophen
- Benzodiazepines
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benzphetamine
- Brompheniramine; Carbetapentane; Phenylephrine
- Brompheniramine; Guaifenesin; Hydrocodone
- Brompheniramine; Hydrocodone; Pseudoephedrine
- Buprenorphine
- Buprenorphine; Naloxone
- Buspirone
- Butabarbital
- Butorphanol
- Cannabidiol
- Capsaicin; Metaxalone
- Carbetapentane; Chlorpheniramine
- Carbetapentane; Chlorpheniramine; Phenylephrine
- Carbetapentane; Diphenhydramine; Phenylephrine
- Carbetapentane; Guaifenesin
- Carbetapentane; Guaifenesin; Phenylephrine
- Carbetapentane; Phenylephrine
- Carbetapentane; Phenylephrine; Pyrilamine
- Carbetapentane; Pseudoephedrine
- Carbetapentane; Pyrilamine
- Carbidopa; Levodopa; Entacapone
- Carbinoxamine; Hydrocodone; Phenylephrine
- Carbinoxamine; Hydrocodone; Pseudoephedrine
- Carisoprodol
- Celecoxib
- Cenobamate
- Cetirizine
- Cetirizine; Pseudoephedrine
- Chlorpheniramine; Codeine
- Chlorpheniramine; Dihydrocodeine; Phenylephrine
- Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
- Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
- Chlorpheniramine; Hydrocodone
- Chlorpheniramine; Hydrocodone; Phenylephrine
- Chlorpheniramine; Hydrocodone; Pseudoephedrine
- Chlorpromazine
- Chlorzoxazone
- Cinacalcet
- Citalopram
- Clobazam
- Clozapine
- Cobicistat
- Codeine
- Codeine; Guaifenesin
- Codeine; Phenylephrine; Promethazine
- Codeine; Promethazine
- COMT inhibitors
- Cyclobenzaprine
- Dacomitinib
- Dantrolene
- Daratumumab; Hyaluronidase
- Darifenacin
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Delavirdine
- Desloratadine
- Desloratadine; Pseudoephedrine
- Desvenlafaxine
- Deutetrabenazine
- Dexmedetomidine
- Dextroamphetamine
- Dextromethorphan; Promethazine
- Dihydrocodeine; Guaifenesin; Pseudoephedrine
- Diphenhydramine; Hydrocodone; Phenylephrine
- Disopyramide
- Donepezil
- Donepezil; Memantine
- Dronabinol
- Dronedarone
- Droperidol
- Duloxetine
- Eliglustat
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Entacapone
- Escitalopram
- Esketamine
- Eszopiclone
- Ethanol
- Etomidate
- Ezogabine
- Fedratinib
- Fentanyl
- Flibanserin
- Fluoxetine
- Fluoxetine; Olanzapine
- Fluphenazine
- Fluvoxamine
- Fospropofol
- Gabapentin
- Galantamine
- Givosiran
- grapefruit juice
- Guaifenesin; Hydrocodone
- Guaifenesin; Hydrocodone; Pseudoephedrine
- Halogenated Anesthetics
- Haloperidol
- Heparin
- Homatropine; Hydrocodone
- Hyaluronidase
- Hyaluronidase, Recombinant; Immune Globulin
- Hydantoins
- Hydrocodone
- Hydrocodone; Ibuprofen
- Hydrocodone; Phenylephrine
- Hydrocodone; Potassium Guaiacolsulfonate
- Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
- Hydrocodone; Pseudoephedrine
- Hydromorphone
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibuprofen; Oxycodone
- Iloperidone
- Imatinib
- Isocarboxazid
- Ketamine
- Lasmiditan
- Lemborexant
- Levocetirizine
- Levomethadyl
- Levomilnacipran
- Levorphanol
- Linezolid
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- Quetiapine
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- Rituximab; Hyaluronidase
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- Secobarbital
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- Solifenacin
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