Brompheniramine Dextromethorphan Guaifenesin

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Brompheniramine Dextromethorphan Guaifenesin Brand Name– Tusnel

What is Brompheniramine Dextromethorphan Guaifenesin

Brompheniramine dextromethorphan guaifenesin are used together in oral preparations to relieve symptoms associated with allergic rhinitis, the common cold or other minor throat or bronchial irritants.

These symptoms include cough, rhinorrhea, sneezing, and watery eyes. Brompheniramine is a first-generation sedating antihistamine (H1-blocker) of the propylamine class. It dries the nasal and sinus passages secondary to its anticholinergic activity.

Dextromethorphan is a centrally acting cough suppressant.

Guaifenesin loosens and thins phlegm and bronchial secretions to ease expectoration.

Although guaifenesin may be used as an expectorant in both productive and non-productive coughs, it is especially useful in the treatment of dry, non-productive coughs which tend to injure the respiratory mucous membranes.

Indications

  1. allergic rhinitis
  2. common cold
  3. cough
  4. rhinorrhea
  5. sneezing

For the relief of cough, rhinorrhea, sneezing, and watery eyes due to allergic rhinitis, the common cold, or other inhaled irritants

Side Effects

  1. abdominal pain
  2. anorexia
  3. blurred vision
  4. confusion
  5. constipation
  6. delirium
  7. diarrhea
  8. diplopia
  9. dizziness
  10. drowsiness
  11. dysarthria
  12. dyskinesia
  13. dyspepsia
  14. dysuria
  15. euphoria
  16. excitability
  17. hallucinations
  18. hypertension
  19. hypotension
  20. impotence (erectile dysfunction)
  21. insomnia
  22. irritability
  23. lethargy
  24. nausea
  25. palpitations
  26. rash
  27. respiratory depression
  28. restlessness
  29. seizures
  30. serotonin syndrome
  31. sinus tachycardia
  32. tinnitus
  33. tremor
  34. urinary retention
  35. urticaria
  36. vertigo
  37. visual impairment
  38. vomiting
  39. weakness
  40. xerophthalmia
  41. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • anticholinergic medications
  • asthma
  • bladder obstruction
  • breast-feeding
  • bronchitis
  • cardiac disease
  • children
  • chronic obstructive pulmonary disease (COPD)
  • closed-angle glaucoma
  • contact lenses
  • driving or operating machinery
  • emphysema
  • geriatric
  • GI obstruction
  • hepatic disease
  • hypertension
  • hyperthyroidism
  • ileus
  • increased intraocular pressure
  • infants
  • MAOI therapy
  • neonates
  • pregnancy
  • prostatic hypertrophy
  • seizure disorder
  • seizures
  • status asthmaticus
  • tobacco smoking
  • urinary retention

Interactions

  • Abiraterone
  • Acetaminophen; Butalbital
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Codeine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Propoxyphene
  • Acetaminophen; Tramadol
  • Alfentanil
  • Alosetron
  • Amantadine
  • Ambenonium Chloride
  • Amiodarone
  • Amlodipine; Celecoxib
  • Amobarbital
  • Amoxapine
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamine; Dextroamphetamine Salts
  • Anticholinergics
  • Apomorphine
  • Aripiprazole
  • Artemether; Lumefantrine
  • Asenapine
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Oxycodone
  • Atazanavir; Cobicistat
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Azelastine
  • Azelastine; Fluticasone
  • Baclofen
  • Barbiturates
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benzhydrocodone; Acetaminophen
  • Benzodiazepines
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzphetamine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Buprenorphine
  • Buprenorphine; Naloxone
  • Buspirone
  • Butabarbital
  • Butorphanol
  • Cannabidiol
  • Capsaicin; Metaxalone
  • Carbetapentane; Chlorpheniramine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carisoprodol
  • Celecoxib
  • Cenobamate
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpromazine
  • Chlorzoxazone
  • Cinacalcet
  • Citalopram
  • Clobazam
  • Clozapine
  • Cobicistat
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • COMT inhibitors
  • Cyclobenzaprine
  • Dacomitinib
  • Dantrolene
  • Daratumumab; Hyaluronidase
  • Darifenacin
  • Darunavir; Cobicistat
  • Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
  • Delavirdine
  • Desloratadine
  • Desloratadine; Pseudoephedrine
  • Desvenlafaxine
  • Deutetrabenazine
  • Dexmedetomidine
  • Dextroamphetamine
  • Dextromethorphan; Promethazine
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Disopyramide
  • Donepezil
  • Donepezil; Memantine
  • Dronabinol
  • Dronedarone
  • Droperidol
  • Duloxetine
  • Eliglustat
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Entacapone
  • Escitalopram
  • Esketamine
  • Eszopiclone
  • Ethanol
  • Etomidate
  • Ezogabine
  • Fedratinib
  • Fentanyl
  • Flibanserin
  • Fluoxetine
  • Fluoxetine; Olanzapine
  • Fluphenazine
  • Fluvoxamine
  • Fospropofol
  • Gabapentin
  • Galantamine
  • Givosiran
  • grapefruit juice
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Halogenated Anesthetics
  • Haloperidol
  • Heparin
  • Homatropine; Hydrocodone
  • Hyaluronidase
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydantoins
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibuprofen; Oxycodone
  • Iloperidone
  • Imatinib
  • Isocarboxazid
  • Ketamine
  • Lasmiditan
  • Lemborexant
  • Levocetirizine
  • Levomethadyl
  • Levomilnacipran
  • Levorphanol
  • Linezolid
  • Lithium
  • Lofexidine
  • Loratadine
  • Loratadine; Pseudoephedrine
  • Lorcaserin
  • Loxapine
  • Lumateperone
  • Lurasidone
  • Magnesium Salts
  • Maprotiline
  • Meclizine
  • Melatonin
  • Memantine
  • Meperidine
  • Meperidine; Promethazine
  • Mephobarbital
  • Meprobamate
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methocarbamol
  • Methohexital
  • Methylene Blue
  • Metoclopramide
  • Metyrapone
  • Metyrosine
  • Milnacipran
  • Minocycline
  • Mirabegron
  • Mirtazapine
  • Mitotane
  • Molindone
  • Monoamine oxidase inhibitors
  • Morphine
  • Morphine; Naltrexone
  • Nabilone
  • Nalbuphine
  • Nefazodone
  • Olanzapine
  • Opiate Agonists
  • Oritavancin
  • Orphenadrine
  • Oxycodone
  • Oxymorphone
  • Ozanimod
  • Paliperidone
  • Panobinostat
  • Paroxetine
  • Pazopanib
  • Peginterferon Alfa-2b
  • Pentazocine
  • Pentazocine; Naloxone
  • Pentobarbital
  • Perampanel
  • Perphenazine
  • Perphenazine; Amitriptyline
  • Phenelzine
  • Phenobarbital
  • Phenylephrine; Promethazine
  • Pimozide
  • Pitolisant
  • Pramipexole
  • Pregabalin
  • Primidone
  • Procarbazine
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Propofol
  • Propoxyphene
  • Quetiapine
  • Quinine
  • Ramelteon
  • Rasagiline
  • Remifentanil
  • Risperidone
  • Rituximab; Hyaluronidase
  • Rivastigmine
  • Rolapitant
  • Ropinirole
  • Safinamide
  • Secobarbital
  • Selegiline
  • Serotonin-Receptor Agonists
  • Sertraline
  • Sibutramine
  • Sincalide
  • Sodium Iodide
  • Solifenacin
  • St. John’s Wort, Hypericum perforatum
  • Sufentanil
  • Suvorexant
  • Tacrine
  • Tapentadol
  • Tasimelteon
  • Tedizolid
  • Terbinafine
  • Thalidomide
  • Thiopental
  • Thioridazine
  • Thiothixene
  • Tizanidine
  • Tocilizumab
  • Tolcapone
  • Tramadol
  • Tranylcypromine
  • Trastuzumab; Hyaluronidase
  • Trazodone
  • Tricyclic antidepressants
  • Trifluoperazine
  • Trimethobenzamide
  • Trospium
  • Vemurafenib
  • Venlafaxine
  • Vigabatrin
  • Vilazodone
  • Vortioxetine
  • Zaleplon
  • Ziconotide
  • Ziprasidone
  • Zolpidem

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