Amlodipine

Amlodipine Brand Name– Katerzia | Norvasc

What is Amlodipine

Amlodipine is an oral calcium-channel blocker. It is used for the treatment of hypertension, chronic stable angina pectoris, and Prinzmetal’s variant angina.

Amlodipine is considered less effective than ACE inhibitors or AII-receptor antagonists in slowing the progression of renal disease in patients with diabetic nephropathy or hypertensive renal disease.

Amlodipine is a potent peripheral vasodilator, similar to nifedipine and other members of the dihydropyridine class, although amlodipine has the longest half-life of the group, thus allowing for once-daily dosing.

The CAMELOT trial demonstrated that amlodipine use in patients with documented coronary artery disease CAD results in reduced coronary revascularization procedures and reduced hospitalizations due to angina.

Indications

  1. angina
  2. coronary artery disease
  3. hypertension
  4. variant angina

Side Effects

  1. abdominal pain
  2. angina
  3. angioedema
  4. anorexia
  5. anxiety
  6. arrhythmia exacerbation
  7. arthralgia
  8. asthenia
  9. atrial fibrillation
  10. back pain
  11. bradycardia
  12. chest pain (unspecified)
  13. chills
  14. conjunctivitis
  15. constipation
  16. depression
  17. diaphoresis
  18. diarrhea
  19. diplopia
  20. dizziness
  21. drowsiness
  22. dysphagia
  23. dyspnea
  24. edema
  25. elevated hepatic enzymes
  26. epistaxis
  27. erythema
  28. erythema multiforme
  29. fatigue
  30. flatulence
  31. flushing
  32. gingival hyperplasia
  33. gynecomastia
  34. hepatitis
  35. hot flashes
  36. hyperglycemia
  37. hypoesthesia
  38. hypotension
  39. impotence (erectile dysfunction)
  40. increased urinary frequency
  41. insomnia
  42. jaundice
  43. leukopenia
  44. libido decrease
  45. maculopapular rash
  46. malaise
  47. muscle cramps
  48. myalgia
  49. myocardial infarction
  50. nausea
  51. nightmares
  52. nocturia
  53. ocular pain
  54. orthostatic hypotension
  55. palpitations
  56. pancreatitis
  57. paresthesias
  58. peripheral edema
  59. peripheral neuropathy
  60. polydipsia
  61. pruritus
  62. purpura
  63. rash
  64. sinus tachycardia
  65. syncope
  66. thrombocytopenia
  67. tinnitus
  68. tremor
  69. vasculitis
  70. ventricular tachycardia
  71. vertigo
  72. visual impairment
  73. vomiting
  74. weight gain
  75. weight loss
  76. xerostomia

Monitoring Parameters

  • blood pressure

Contraindications

  • acute myocardial infarction
  • aortic stenosis
  • breast-feeding
  • coronary artery disease
  • geriatric
  • hepatic disease
  • pregnancy

Interactions

  • Acebutolol
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Codeine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Propoxyphene
  • Acetaminophen; Pseudoephedrine
  • Acetaminophen; Tramadol
  • Acrivastine; Pseudoephedrine
  • Aldesleukin, IL-2
  • Alemtuzumab
  • Alfentanil
  • Alprostadil
  • Amifostine
  • Aminolevulinic Acid
  • Amiodarone
  • Amlodipine; Celecoxib
  • Amoxicillin; Clarithromycin; Lansoprazole
  • Amoxicillin; Clarithromycin; Omeprazole
  • Amphetamine; Dextroamphetamine Salts
  • Amprenavir
  • Amyl Nitrite
  • Apalutamide
  • Apomorphine
  • Apraclonidine
  • Aprepitant, Fosaprepitant
  • Aripiprazole
  • Armodafinil
  • Asenapine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Oxycodone
  • Atazanavir
  • Atazanavir; Cobicistat
  • Atenolol
  • Atenolol; Chlorthalidone
  • Avanafil
  • Baclofen
  • Barbiturates
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Bendroflumethiazide; Nadolol
  • Benzhydrocodone; Acetaminophen
  • Benzonatate
  • Benzphetamine
  • Beta-blockers
  • Betaxolol
  • Bexarotene
  • Bisoprolol
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Boceprevir
  • Bortezomib
  • Bosentan
  • Brimonidine; Timolol
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Bupivacaine; Lidocaine
  • Cabergoline
  • Caffeine; Ergotamine
  • Carbamazepine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbidopa; Levodopa
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Carteolol
  • Carvedilol
  • Celecoxib
  • Cenobamate
  • Ceritinib
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chloramphenicol
  • Chloroprocaine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Ciprofloxacin
  • Cisapride
  • Clarithromycin
  • Clobazam
  • Clopidogrel
  • Clozapine
  • Co-Enzyme Q10, Ubiquinone
  • Cobicistat
  • Cocaine
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • Colchicine
  • Colchicine; Probenecid
  • Conivaptan
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  • Cyclosporine
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  • Danazol
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  • Deferasirox
  • Delavirdine
  • Desloratadine; Pseudoephedrine
  • Dexamethasone
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  • Dextromethorphan; Quinidine
  • Diazoxide
  • Diclofenac
  • Diclofenac; Misoprostol
  • Diethylpropion
  • Diflunisal
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Dihydroergotamine
  • Diltiazem
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dofetilide
  • Dorzolamide; Timolol
  • Dronabinol
  • Dronedarone
  • Drospirenone; Ethinyl Estradiol
  • Drospirenone; Ethinyl Estradiol; Levomefolate
  • Duloxetine
  • Dutasteride; Tamsulosin
  • Duvelisib
  • Efavirenz
  • Efavirenz; Emtricitabine; Tenofovir
  • Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
  • Elagolix
  • Elagolix; Estradiol; Norethindrone acetate
  • Elbasvir; Grazoprevir
  • Eliglustat
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Enflurane
  • Enzalutamide
  • Ephedrine
  • Epirubicin
  • Eplerenone
  • Epoprostenol
  • Ergonovine
  • Ergotamine
  • Erythromycin
  • Erythromycin; Sulfisoxazole
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  • Estradiol
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  • Ethinyl Estradiol; Norethindrone Acetate
  • Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
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  • Ethinyl Estradiol; Norgestimate
  • Ethinyl Estradiol; Norgestrel
  • Ethosuximide
  • Ethotoin
  • Etodolac
  • Etomidate
  • Etravirine
  • Everolimus
  • Ezetimibe; Simvastatin
  • Famotidine; Ibuprofen
  • Fedratinib
  • Fenoprofen
  • Fentanyl
  • Fexofenadine; Pseudoephedrine
  • Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
  • Fluconazole
  • Fluoxetine
  • Fluoxetine; Olanzapine
  • Flurbiprofen
  • Flutamide
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  • Fosamprenavir
  • Fosphenytoin
  • Fospropofol
  • General anesthetics
  • Ginkgo, Ginkgo biloba
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  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Pseudoephedrine
  • Haloperidol
  • Halothane
  • Homatropine; Hydrocodone
  • Hydantoins
  • Hydralazine; Isosorbide Dinitrate, ISDN
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Ibuprofen
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Idelalisib
  • Iloperidone
  • Iloprost
  • Imatinib
  • Indinavir
  • Indomethacin
  • Intravenous Lipid Emulsions
  • Isavuconazonium
  • Isocarboxazid
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  • Isoproterenol
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  • Itraconazole
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  • Naproxen; Pseudoephedrine
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  • Paliperidone
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  • Phenylephrine
  • Phenylephrine; Promethazine
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  • Prazosin
  • Procainamide
  • Procaine
  • Propofol
  • Propoxyphene
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  • Protease inhibitors
  • Pseudoephedrine
  • Quinidine
  • Quinine
  • Rasagiline
  • Remifentanil
  • Ribociclib
  • Ribociclib; Letrozole
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Risperidone
  • Ritonavir
  • Rofecoxib
  • Saquinavir
  • Segesterone Acetate; Ethinyl Estradiol
  • Selegiline
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  • Sildenafil
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  • Simvastatin; Sitagliptin
  • Sincalide
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  • Sofosbuvir; Velpatasvir
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  • Sotalol
  • St. John’s Wort, Hypericum perforatum
  • Sufentanil
  • Sulindac
  • Tacrolimus
  • Tamsulosin
  • Telaprevir
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  • Thalidomide
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  • Timolol
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  • Tramadol
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  • Vemurafenib
  • Verapamil
  • Verteporfin
  • Vinorelbine
  • Voriconazole
  • Yohimbine
  • Zafirlukast
  • Ziprasidone
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