Aliskiren Amlodipine Hydrochlorothiazide

Aliskiren Amlodipine Hydrochlorothiazide Brand Name– Amturnide

What is Aliskiren Amlodipine Hydrochlorothiazide

Aliskiren Amlodipine Hydrochlorothiazide is a combination product for the treatment of hypertension.

Aliskiren Amlodipine Hydrochlorothiazide is not indicated for the initial treatment of hypertension, as the product contains fixed doses of 3 different antihypertensive drugs: aliskiren is a direct renin inhibitor; amlodipine is a dihydropyridine calcium-channel blocker; and hydrochlorothiazide is a thiazide diuretic.

Combining drugs from complimentary classes is significantly more effective in lowering blood pressure than increasing the dose of one drug. The combination of a renin inhibitor with a low-dose, thiazide diuretic results in additive blood pressure reduction and combining a diuretic with a calcium-channel blocker also results in additive BP reduction.

The combination of a calcium-channel blocker with a renin inhibitor produces complimentary effects on the renin system, sympathetic activity, and vascular endothelial function.

Additionally, calcium-channel blockers produce a direct relaxant effect on vascular smooth muscle, which augments the blood pressure lowering effect of direct renin inhibitors.

When compared to similar doses of dual combination therapy with either aliskiren; amlodipine 300/10 mg/day PO, aliskiren; hydrochlorothiazide 300/25 mg/day PO, or amlodipine; hydrochlorothiazide 10/25 mg/day PO, triple therapy with aliskiren; amlodipine; hydrochlorothiazide 300/10/25 mg/day PO resulted in significantly greater blood pressure reductions (36.3/20.2 mmHg for triple therapy vs. 30.8/18.7 mmHg for aliskiren; amlodipine, 28.3/12.7 mmHg aliskiren; hydrochlorothiazide, and 31/15.3 mmHg for amlodipine; hydrochlorothiazide).

Aliskiren Amlodipine Hydrochlorothiazide was approved by the FDA in December 2010.

Indications

  • hypertension

Side Effects

  1. abdominal pain
  2. agranulocytosis
  3. anaphylactoid reactions
  4. anemia
  5. angioedema
  6. anorexia
  7. anxiety
  8. aplastic anemia
  9. arrhythmia exacerbation
  10. arthralgia
  11. asthenia
  12. atrial fibrillation
  13. azotemia
  14. back pain
  15. blurred vision
  16. bradycardia
  17. chest pain (unspecified)
  18. cholestasis
  19. conjunctivitis
  20. constipation
  21. cough
  22. depression
  23. diaphoresis
  24. diarrhea
  25. diplopia
  26. dizziness
  27. dyspepsia
  28. dysphagia
  29. dyspnea
  30. elevated hepatic enzymes
  31. epistaxis
  32. erythema
  33. erythema multiforme
  34. exfoliative dermatitis
  35. fever
  36. flatulence
  37. flushing
  38. gastroesophageal reflux
  39. gingival hyperplasia
  40. glycosuria
  41. gout
  42. gynecomastia
  43. headache
  44. hemolytic anemia
  45. hepatitis
  46. hyperbilirubinemia
  47. hypercholesterolemia
  48. hyperglycemia
  49. hyperkalemia
  50. hypertriglyceridemia
  51. hyperuricemia
  52. hypochloremia
  53. hypokalemia
  54. hypomagnesemia
  55. hyponatremia
  56. hypotension
  57. impotence (erectile dysfunction)
  58. increased urinary frequency
  59. insomnia
  60. interstitial nephritis
  61. jaundice
  62. leukopenia
  63. libido decrease
  64. maculopapular rash
  65. malaise
  66. metabolic alkalosis
  67. muscle cramps
  68. myalgia
  69. myopia
  70. nephrolithiasis
  71. nightmares
  72. nocturia
  73. ocular hypertension
  74. ocular pain
  75. orthostatic hypotension
  76. pancreatitis
  77. paresthesias
  78. peripheral edema
  79. peripheral neuropathy
  80. pharyngitis
  81. photosensitivity
  82. pneumonitis
  83. pruritus
  84. pulmonary edema
  85. purpura
  86. renal failure (unspecified)
  87. restlessness
  88. seizures
  89. sialadenitis
  90. Stevens-Johnson syndrome
  91. syncope
  92. teratogenesis
  93. thrombocytopenia
  94. tinnitus
  95. toxic epidermal necrolysis
  96. tremor
  97. urticaria
  98. vasculitis
  99. ventricular tachycardia
  100. vertigo
  101. visual impairment
  102. vomiting
  103. weight gain
  104. weight loss
  105. xanthopsia
  106. xerostomia

Monitoring Parameters

  • blood glucose
  • blood pressure
  • heart rate
  • serum calcium
  • serum creatinine/BUN
  • serum electrolytes
  • serum magnesium
  • serum uric acid

Contraindications

  • ACE-inhibitor induced angioedema
  • acid/base imbalance
  • angina
  • angioedema
  • anuria
  • aortic stenosis
  • asthma
  • biliary cirrhosis
  • Black patients
  • breast-feeding
  • children
  • coronary artery disease
  • diabetes mellitus
  • electrolyte imbalance
  • gastroesophageal reflux disease (GERD)
  • geriatric
  • gout
  • heart failure
  • hepatic disease
  • hereditary angioedema
  • hiatal hernia
  • hyperaldosteronism
  • hypercalcemia
  • hyperkalemia
  • hyperuricemia
  • hypochloremia
  • hypokalemia
  • hypomagnesemia
  • hyponatremia
  • hypotension
  • hypovolemia
  • infants
  • metabolic alkalosis
  • myocardial infarction
  • neonates
  • orthostatic hypotension
  • penicillin hypersensitivity
  • pregnancy
  • renal artery stenosis
  • renal failure
  • renal impairment
  • sulfonamide hypersensitivity
  • sunlight (UV) exposure
  • surgery
  • sympathectomy
  • systemic lupus erythematosus (SLE)
  • thiazide diuretic hypersensitivity

Interactions

  • Acarbose
  • Acebutolol
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Codeine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Propoxyphene
  • Acetaminophen; Pseudoephedrine
  • Acetaminophen; Tramadol
  • Acetazolamide
  • Acetohexamide
  • Aclidinium; Formoterol
  • Acrivastine; Pseudoephedrine
  • Albiglutide
  • Albuterol
  • Albuterol; Ipratropium
  • Aldesleukin, IL-2
  • Alemtuzumab
  • Alendronate; Cholecalciferol
  • Alfentanil
  • Aliskiren; Valsartan
  • Allopurinol
  • Alogliptin
  • Alogliptin; Metformin
  • Alogliptin; Pioglitazone
  • Alpha-glucosidase Inhibitors
  • Alprostadil
  • Amifostine
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminolevulinic Acid
  • Amiodarone
  • Amlodipine; Atorvastatin
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Amobarbital
  • Amoxicillin; Clarithromycin; Lansoprazole
  • Amoxicillin; Clarithromycin; Omeprazole
  • Amphetamine; Dextroamphetamine Salts
  • Amphotericin B
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  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
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  • Avanafil
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  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril
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  • Benzhydrocodone; Acetaminophen
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzonatate
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  • Brompheniramine; Carbetapentane; Phenylephrine
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  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide; Formoterol
  • Bumetanide
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  • Buprenorphine
  • Buprenorphine; Naloxone
  • Cabergoline
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  • Calcium
  • Calcium Phosphate, Supersaturated
  • Calcium; Vitamin D
  • Canagliflozin
  • Canagliflozin; Metformin
  • Candesartan
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  • Captopril
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  • Carbamazepine
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  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbidopa; Levodopa
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Cariprazine
  • Carteolol
  • Carvedilol
  • Celecoxib
  • Cenobamate
  • Ceritinib
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chloramphenicol
  • Chlordiazepoxide; Clidinium
  • Chloroprocaine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorpropamide
  • Cholestyramine
  • Cidofovir
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  • Cocaine
  • Codeine
  • Codeine; Guaifenesin
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  • Codeine; Promethazine
  • Colchicine
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  • Deferasirox
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  • Desvenlafaxine
  • Dexamethasone
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexlansoprazole
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  • Dexmethylphenidate
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  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Dextromethorphan; Guaifenesin; Potassium Guaiacolsulfonate
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Dextromethorphan; Quinidine
  • Diazoxide
  • Dichlorphenamide
  • Diclofenac
  • Diclofenac; Misoprostol
  • Dicyclomine
  • Diethylpropion
  • Diflunisal
  • Digitoxin
  • Digoxin
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Dihydroergotamine
  • Diltiazem
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dobutamine
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  • Dolasetron
  • Donepezil; Memantine
  • Dopamine
  • Dorzolamide; Timolol
  • Doxacurium
  • Dronabinol
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  • Droperidol
  • Drospirenone
  • Drospirenone; Estradiol
  • Drospirenone; Ethinyl Estradiol
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  • Dulaglutide
  • Duloxetine
  • Dutasteride; Tamsulosin
  • Duvelisib
  • Efavirenz
  • Efavirenz; Emtricitabine; Tenofovir
  • Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
  • Elagolix
  • Elbasvir; Grazoprevir
  • Eliglustat
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Enalapril, Enalaprilat
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Enflurane
  • Enzalutamide
  • Ephedrine
  • Epinephrine
  • Epirubicin
  • Eplerenone
  • Epoprostenol
  • Eprosartan
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Ergocalciferol, Vitamin D2
  • Ergonovine
  • Ergotamine
  • Ertugliflozin; Metformin
  • Ertugliflozin; Sitagliptin
  • Erythromycin
  • Erythromycin; Sulfisoxazole
  • Escitalopram
  • Eslicarbazepine
  • Esmolol
  • Esomeprazole
  • Esomeprazole; Naproxen
  • Estradiol
  • Estradiol Cypionate; Medroxyprogesterone
  • Ethacrynic Acid
  • Ethanol
  • Ethinyl Estradiol
  • Ethinyl Estradiol; Desogestrel
  • Ethinyl Estradiol; Ethynodiol Diacetate
  • Ethinyl Estradiol; Etonogestrel
  • Ethinyl Estradiol; Levonorgestrel
  • Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
  • Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
  • Ethinyl Estradiol; Norelgestromin
  • Ethinyl Estradiol; Norethindrone
  • Ethinyl Estradiol; Norethindrone Acetate
  • Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
  • Ethinyl Estradiol; Norethindrone; Ferrous fumarate
  • Ethinyl Estradiol; Norgestimate
  • Ethinyl Estradiol; Norgestrel
  • Ethosuximide
  • Ethotoin
  • Etodolac
  • Etomidate
  • Etravirine
  • Everolimus
  • Exenatide
  • Ezetimibe; Simvastatin
  • Famotidine; Ibuprofen
  • Fedratinib
  • Fenoldopam
  • Fenoprofen
  • Fentanyl
  • Fexofenadine; Pseudoephedrine
  • Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
  • Flavoxate
  • Fluconazole
  • Fluocinolone; Hydroquinone; Tretinoin
  • Fluoxetine
  • Fluoxetine; Olanzapine
  • Flurbiprofen
  • Flutamide
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • Fluvoxamine
  • Formoterol
  • Formoterol; Mometasone
  • Fosamprenavir
  • Fosinopril
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Fosphenytoin
  • Fospropofol
  • Fostamatinib
  • Furosemide
  • Gallium Ga 68 Dotatate
  • General anesthetics
  • Ginkgo, Ginkgo biloba
  • Ginseng, Panax ginseng
  • Glecaprevir; Pibrentasvir
  • Glimepiride
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glipizide
  • Glipizide; Metformin
  • Glyburide
  • Glyburide; Metformin
  • Glycopyrrolate
  • Glycopyrrolate; Formoterol
  • Granisetron
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Potassium Guaiacolsulfonate
  • Guaifenesin; Pseudoephedrine
  • Halobetasol; Tazarotene
  • Halofantrine
  • Haloperidol
  • Halothane
  • Hetastarch; Dextrose; Electrolytes
  • Homatropine; Hydrocodone
  • Hydantoins
  • Hydralazine
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydralazine; Isosorbide Dinitrate, ISDN
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Hyoscyamine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibritumomab Tiuxetan
  • Ibuprofen
  • Ibuprofen lysine
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Icosapent ethyl
  • Idelalisib
  • Iloperidone
  • Iloprost
  • Imatinib
  • Inamrinone
  • Incretin Mimetics
  • Indacaterol
  • Indacaterol; Glycopyrrolate
  • Indapamide
  • Indinavir
  • Indomethacin
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  • Insulins
  • Intravenous Lipid Emulsions
  • Iodine; Potassium Iodide, KI
  • Irbesartan
  • Isavuconazonium
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  • Isoflurane
  • Isoniazid, INH; Pyrazinamide, PZA; Rifampin
  • Isoniazid, INH; Rifampin
  • Isoproterenol
  • Isosorbide Dinitrate, ISDN
  • Isosorbide Mononitrate
  • Itraconazole
  • Ketamine
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  • Ketoprofen
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  • Labetalol
  • Lacosamide
  • Lanreotide
  • Lansoprazole
  • Lansoprazole; Naproxen
  • Lasmiditan
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  • Lidocaine
  • Linagliptin
  • Linagliptin; Metformin
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  • Lisinopril
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  • Loperamide
  • Loperamide; Simethicone
  • Lopinavir; Ritonavir
  • Loratadine; Pseudoephedrine
  • Lorlatinib
  • Losartan
  • Lovastatin
  • Lovastatin; Niacin
  • Lumacaftor; Ivacaftor
  • Lumacaftor; Ivacaftor
  • Lurasidone
  • Magnesium Salts
  • Magnesium Sulfate; Potassium Sulfate; Sodium Sulfate
  • Mannitol
  • Maraviroc
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Meglitinides
  • Meloxicam
  • Memantine
  • Mepenzolate
  • Meperidine
  • Meperidine; Promethazine
  • Mepivacaine
  • Mepivacaine; Levonordefrin
  • Mequinol; Tretinoin
  • Mestranol; Norethindrone
  • Metaproterenol
  • Metformin
  • Metformin; Pioglitazone
  • Metformin; Repaglinide
  • Metformin; Rosiglitazone
  • Metformin; Saxagliptin
  • Metformin; Sitagliptin
  • Methadone
  • Methamphetamine
  • Methazolamide
  • Methenamine
  • Methenamine; Sodium Acid Phosphate
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methotrexate
  • Methoxsalen
  • Methscopolamine
  • Methylergonovine
  • Methylphenidate
  • Methysergide
  • Metoclopramide
  • Metoprolol
  • Midodrine
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  • Minoxidil
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  • Mitotane
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  • Modafinil
  • Moexipril
  • Morphine
  • Morphine; Naltrexone
  • Nabumetone
  • Nadolol
  • Nafcillin
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Nateglinide
  • Nebivolol
  • Nebivolol; Valsartan
  • Nefazodone
  • Nelfinavir
  • Nesiritide, BNP
  • Netupitant, Fosnetupitant; Palonosetron
  • Neuromuscular blockers
  • Nevirapine
  • Niacin, Niacinamide
  • Niacin; Simvastatin
  • Nilotinib
  • Nitrates
  • Nitroglycerin
  • Nitroprusside
  • Nonsteroidal antiinflammatory drugs
  • Norepinephrine
  • Octreotide
  • Olanzapine
  • Olmesartan
  • Olodaterol
  • Ombitasvir; Paritaprevir; Ritonavir
  • Omeprazole
  • Omeprazole; Amoxicillin; Rifabutin
  • Omeprazole; Sodium Bicarbonate
  • Ondansetron
  • Oprelvekin, rh-IL-11
  • Oritavancin
  • Oxaprozin
  • Oxcarbazepine
  • Oxybutynin
  • Oxycodone
  • Oxymetazoline
  • Oxymorphone
  • Paliperidone
  • Pancuronium
  • Pantoprazole
  • Paroxetine
  • Pasireotide
  • Pazopanib
  • Penbutolol
  • Pentamidine
  • Pentazocine
  • Pentazocine; Naloxone
  • Pentoxifylline
  • Perampanel
  • Perindopril
  • Perindopril; Amlodipine
  • Phendimetrazine
  • Phenelzine
  • Phenothiazines
  • Phentermine
  • Phentermine; Topiramate
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Phenytoin
  • Photosensitizing agents (topical)
  • Pimozide
  • Pindolol
  • Pioglitazone
  • Pirbuterol
  • Piroxicam
  • Polycarbophil
  • Polyethylene Glycol; Electrolytes
  • Polyethylene Glycol; Electrolytes; Ascorbic Acid
  • Ponatinib
  • Porfimer
  • Posaconazole
  • Potassium
  • Potassium Acetate
  • Potassium Bicarbonate
  • Potassium Chloride
  • Potassium Citrate
  • Potassium Gluconate
  • Potassium Iodide, KI
  • Potassium-sparing diuretics
  • Pramlintide
  • Prazosin
  • Prilocaine; Epinephrine
  • Probenecid
  • Procainamide
  • Procaine
  • Propantheline
  • Propofol
  • Propoxyphene
  • Propranolol
  • Protease inhibitors
  • Pseudoephedrine
  • Quetiapine
  • Quinapril
  • Quinidine
  • Quinine
  • Rabeprazole
  • Ramipril
  • Rapacuronium
  • Rasagiline
  • Remifentanil
  • Repaglinide
  • Ribociclib
  • Ribociclib; Letrozole
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Risperidone
  • Ritonavir
  • Rocuronium
  • Rofecoxib
  • Rosiglitazone
  • Sacubitril; Valsartan
  • Salicylates
  • Salmeterol
  • Sapropterin
  • Saquinavir
  • Saxagliptin
  • Scopolamine
  • Segesterone Acetate; Ethinyl Estradiol
  • Selegiline
  • Semaglutide
  • Serotonin norepinephrine reuptake inhibitors
  • Sertraline
  • Sevoflurane
  • Sildenafil
  • Silodosin
  • Simeprevir
  • Simvastatin
  • Simvastatin; Sitagliptin
  • Sincalide
  • Sirolimus
  • Sitagliptin
  • Sodium Phosphate Monobasic Monohydrate; Sodium Phosphate Dibasic Anhydrous
  • Sodium picosulfate; Magnesium oxide; Anhydrous citric acid
  • Sofosbuvir; Velpatasvir
  • Sofosbuvir; Velpatasvir; Voxilaprevir
  • Solifenacin
  • Sotalol
  • Spironolactone
  • St. John’s Wort, Hypericum perforatum
  • Streptozocin
  • Succinylcholine
  • Sufentanil
  • Sulfacetamide
  • Sulfacetamide; Sulfur
  • Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
  • Sulfinpyrazone
  • Sulfonylureas
  • Sulindac
  • Tacrolimus
  • Tamsulosin
  • Tapentadol
  • Tazarotene
  • Tegaserod
  • Telaprevir
  • Telithromycin
  • Telmisartan
  • Telotristat Ethyl
  • Temsirolimus
  • Terbutaline
  • Tetrabenazine
  • Tetracaine
  • Thalidomide
  • Thiazolidinediones
  • Thiothixene
  • Timolol
  • Tiotropium; Olodaterol
  • Tipranavir
  • Tizanidine
  • Tolazamide
  • Tolbutamide
  • Tolmetin
  • Tolterodine
  • Tolvaptan
  • Topiramate
  • Toremifene
  • Torsemide
  • Tramadol
  • Trandolapril
  • Trandolapril; Verapamil
  • Tranylcypromine
  • Trazodone
  • Treprostinil
  • Tretinoin, ATRA
  • Triamterene
  • Trihexyphenidyl
  • Trospium
  • Tubocurarine
  • Umeclidinium; Vilanterol
  • Valdecoxib
  • Valproic Acid, Divalproex Sodium
  • Valsartan
  • Vasodilators
  • Vecuronium
  • Vemurafenib
  • Venlafaxine
  • Verapamil
  • Verteporfin
  • Vilazodone
  • Vinorelbine
  • Vitamin D
  • Vitamin D analogs
  • Voriconazole
  • Vorinostat
  • Vortioxetine
  • Warfarin
  • Yohimbine
  • Zafirlukast
  • Ziconotide
  • Ziprasidone
  • Zonisamide
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