Acetaminophen Caffeine Dihydrocodeine

Acetaminophen Caffeine Dihydrocodeine Brand Names

Dvorah | Panlor | Panlor DC | Panlor SS | Trezix | Zerlor

What is Acetaminophen Caffeine Dihydrocodeine

Acetaminophen Caffeine Dihydrocodeine are used together in oral preparations to treat moderate to severe pain.

Acetaminophen is a non-salicylate analgesic, while dihydrocodeine is an opioid analgesic.

The combination of acetaminophen and dihydrocodeine produces a greater analgesic effect than that produced by acetaminophen alone.

Caffeine may augment the analgesic effect and produce fewer adverse reactions than caffeine alone or higher opioid doses, respectively. Use opioid-containing analgesics with caution due to concerns for respiratory depression, substance abuse, and the potential for overdose or poisoning.

Acetaminophen; caffeine; dihydrocodeine is a short-acting combination product and is not indicated for the management of chronic, persistent pain.

Acetaminophen Caffeine Dihydrocodeine was FDA-approved in August 1997.

Indications

• moderate pain
• severe pain

Side Effects

1. abdominal pain
2. acute generalized exanthematous pustulosis (AGEP)
3. adrenocortical insufficiency
4. agranulocytosis
5. amenorrhea
6. anaphylactic shock
7. anaphylactoid reactions
8. angioedema
9. anorexia
10. anxiety
11. confusion
12. constipation
13. contact dermatitis
14. depression
15. diaphoresis
16. diarrhea
17. diuresis
18. dizziness
19. drowsiness
20. dyspepsia
21. edema
22. encephalopathy
23. erythema
24. exfoliative dermatitis
25. fatigue
26. fever
27. flatulence
28. gonadal suppression
29. headache
30. hemolysis
31. hemolytic anemia
32. hepatic necrosis
33. hepatotoxicity
34. hyponatremia
35. impotence (erectile dysfunction)
36. infertility
37. insomnia
38. interstitial nephritis
39. irritability
40. jaundice
41. laryngeal edema
42. leukopenia
43. libido decrease
44. maculopapular rash
45. malaise
46. methemoglobinemia
47. miosis
48. nausea
49. neonatal opioid withdrawal syndrome
50. neutropenia
51. orthostatic hypotension
52. palpitations
53. pancytopenia
54. physiological dependence
55. polyuria
56. pruritus
57. psychological dependence
58. purpura
59. rash
60. renal failure (unspecified)
61. renal papillary necrosis
62. renal tubular necrosis
63. respiratory arrest
64. respiratory depression
65. restlessness
66. rhabdomyolysis
67. scotomata
68. serotonin syndrome
69. SIADH
70. sinus tachycardia
71. thrombocytopenia
72. thrombocytosis
73. tinnitus
74. tolerance
75. toxic epidermal necrolysis
76. tremor
77. urinary retention
78. urticaria
79. vomiting
80. weakness
81. withdrawal
82. xerostomia

Monitoring Parameters

• LFTs
• serum creatinine/BUN: in chronic use or acute toxicity

Contraindications

• abrupt discontinuation
• accidental exposure
• acetaminophen hypersensitivity
• acute abdomen
• acute bronchospasm
• adenoidectomy
• adrenal insufficiency
• alcoholism
• angina
• Asian patients
• asthma
• biliary cirrhosis
• biliary obstruction
• biliary tract disease
• Black patients
• bladder obstruction
• breast-feeding
• cardiac arrhythmias
• cardiac disease
• Caucasian patients
• children
• chronic obstructive pulmonary disease (COPD)
• CNS depression
• coadministration with other CNS depressants
• coma
• constipation
• cor pulmonale
• depression
• diabetes mellitus
• diarrhea
• driving or operating machinery
• ethanol intoxication
• G6PD deficiency
• geriatric
• GI disease
• GI obstruction
• head trauma
• hepatic disease
• hepatic encephalopathy
• hepatitis
• Hispanic patients
• hypertension
• hypotension
• hypothyroidism
• hypovolemia
• hypoxemia
• ileus
• immunosuppression
• increased intracranial pressure
• infants
• infection
• inflammatory bowel disease
• intracranial mass
• labor
• malnutrition
• MAOI therapy
• mental status changes
• myocardial infarction
• myxedema
• neonatal opioid withdrawal syndrome
• neonates
• neuromuscular disease
• obesity
• obstetric delivery
• oliguria
• opiate agonist hypersensitivity
• pancreatitis
• peptic ulcer disease
• potential for overdose or poisoning
• pregnancy
• prostatic hypertrophy
• psychosis
• pulmonary disease
• renal disease
• renal failure
• renal impairment
• respiratory depression
• respiratory infection
• scoliosis
• seizure disorder
• seizures
• shock
• sleep apnea
• status asthmaticus
• substance abuse
• suicidal ideation
• tonsillectomy
• ulcerative colitis
• urethral stricture
• urinary retention
• urinary tract obstruction

Interactions

• Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
• Abiraterone
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital
• Acetaminophen; Butalbital; Caffeine
• Acetaminophen; Butalbital; Caffeine; Codeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
• Acetaminophen; Dextromethorphan; Doxylamine
• Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
• Acetaminophen; Dextromethorphan; Phenylephrine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Dichloralphenazone; Isometheptene
• Acetaminophen; Diphenhydramine
• Acetaminophen; Guaifenesin; Phenylephrine
• Acetaminophen; Hydrocodone
• Acetaminophen; Oxycodone
• Acetaminophen; Pentazocine
• Acetaminophen; Pseudoephedrine
• Acetaminophen; Tramadol
• Aclidinium; Formoterol
• Acrivastine; Pseudoephedrine
• Adenosine
• Albuterol
• Albuterol; Ipratropium
• Aldesleukin, IL-2
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Almotriptan
• Alosetron
• Alprazolam
• Alvimopan
• Amantadine
• Amide local anesthetics
• Amifampridine
• Amiloride; Hydrochlorothiazide, HCTZ
• Amiodarone
• Amitriptyline
• Amitriptyline; Chlordiazepoxide
• Amlodipine
• Amlodipine; Atorvastatin
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Amobarbital
• Amoxapine
• Amoxicillin; Clarithromycin; Lansoprazole
• Amoxicillin; Clarithromycin; Omeprazole
• Amphetamine
• Amphetamine; Dextroamphetamine
• Amphetamine; Dextroamphetamine Salts
• Anagrelide
• Antacids
• Anticholinergics
• Apalutamide
• Apomorphine
• Apraclonidine
• Aprepitant, Fosaprepitant
• Arformoterol
• Aripiprazole
• Armodafinil
• Artemether; Lumefantrine
• Articaine; Epinephrine
• Asenapine
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atazanavir
• Atazanavir; Cobicistat
• Atenolol; Chlorthalidone
• Atropine
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Atropine; Edrophonium
• Atropine; Hyoscyamine; Phenobarbital; Scopolamine
• Azelastine
• Azelastine; Fluticasone
• Azilsartan; Chlorthalidone
• Baclofen
• Barbiturates
• Belladonna Alkaloids; Ergotamine; Phenobarbital
• Belladonna; Opium
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendroflumethiazide; Nadolol
• Benzhydrocodone; Acetaminophen
• Benzodiazepines
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Benzphetamine
• Benztropine
• Beta-agonists
• Bethanechol
• Bexarotene
• Bicalutamide
• Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Boceprevir
• Bosentan
• Brexpiprazole
• Brigatinib
• Brimonidine
• Brimonidine; Brinzolamide
• Brimonidine; Timolol
• Brompheniramine
• Brompheniramine; Carbetapentane; Phenylephrine
• Brompheniramine; Dextromethorphan; Guaifenesin
• Brompheniramine; Guaifenesin; Hydrocodone
• Brompheniramine; Hydrocodone; Pseudoephedrine
• Brompheniramine; Pseudoephedrine
• Budesonide; Formoterol
• Bupivacaine
• Bupivacaine Liposomal
• Bupivacaine; Lidocaine
• Buprenorphine
• Buprenorphine; Naloxone
• Bupropion
• Bupropion; Naltrexone
• Buspirone
• Busulfan
• Butabarbital
• Butorphanol
• Caffeine
• Candesartan; Hydrochlorothiazide, HCTZ
• Cannabidiol
• Capmatinib
• Capsaicin; Metaxalone
• Captopril; Hydrochlorothiazide, HCTZ
• Carbamazepine
• Carbetapentane; Chlorpheniramine
• Carbetapentane; Chlorpheniramine; Phenylephrine
• Carbetapentane; Diphenhydramine; Phenylephrine
• Carbetapentane; Guaifenesin
• Carbetapentane; Guaifenesin; Phenylephrine
• Carbetapentane; Phenylephrine
• Carbetapentane; Phenylephrine; Pyrilamine
• Carbetapentane; Pseudoephedrine
• Carbetapentane; Pyrilamine
• Carbinoxamine
• Carbinoxamine; Dextromethorphan; Pseudoephedrine
• Carbinoxamine; Hydrocodone; Phenylephrine
• Carbinoxamine; Hydrocodone; Pseudoephedrine
• Carbinoxamine; Phenylephrine
• Carbinoxamine; Pseudoephedrine
• Cariprazine
• Carisoprodol
• Celecoxib
• Cenobamate
• Ceritinib
• Cetirizine
• Cetirizine; Pseudoephedrine
• Charcoal
• Chlophedianol; Dexbrompheniramine
• Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
• Chlophedianol; Guaifenesin; Phenylephrine
• Chloral Hydrate
• Chloramphenicol
• Chlorcyclizine
• Chlordiazepoxide
• Chlordiazepoxide; Clidinium
• Chloroprocaine
• Chlorothiazide
• Chlorpheniramine
• Chlorpheniramine; Codeine
• Chlorpheniramine; Dextromethorphan
• Chlorpheniramine; Dextromethorphan; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
• Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Hydrocodone
• Chlorpheniramine; Hydrocodone; Phenylephrine
• Chlorpheniramine; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Phenylephrine
• Chlorpheniramine; Pseudoephedrine
• Chlorpromazine
• Chlorthalidone
• Chlorthalidone; Clonidine
• Chlorzoxazone
• Cholestyramine
• Choline Salicylate; Magnesium Salicylate
• Cimetidine
• Cinacalcet
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clemastine
• Clobazam
• Clomipramine
• Clonazepam
• Clonidine
• Clopidogrel
• Clorazepate
• Clozapine
• Cobicistat
• Codeine; Phenylephrine; Promethazine
• Codeine; Promethazine
• COMT inhibitors
• Conivaptan
• Crizotinib
• Crofelemer
• Cyclizine
• Cyclobenzaprine
• Cyclosporine
• Cyproheptadine
• Dabrafenib
• Dacomitinib
• Dalfopristin; Quinupristin
• Danazol
• Dantrolene
• Dapsone
• Darifenacin
• Darunavir
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
• Deferasirox
• Delavirdine
• Desflurane
• Desipramine
• Desloratadine; Pseudoephedrine
• Desmopressin
• Desvenlafaxine
• Deutetrabenazine
• Dexamethasone
• Dexchlorpheniramine
• Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
• Dexmedetomidine
• Dexmethylphenidate
• Dexpanthenol
• Dextroamphetamine
• Dextromethorphan; Diphenhydramine; Phenylephrine
• Dextromethorphan; Guaifenesin; Phenylephrine
• Dextromethorphan; Guaifenesin; Pseudoephedrine
• Dextromethorphan; Promethazine
• Dextromethorphan; Quinidine
• Diazepam
• Dicyclomine
• Diethylpropion
• Diflunisal
• Dihydrocodeine; Guaifenesin; Pseudoephedrine
• Diltiazem
• Dimenhydrinate
• Diphenhydramine
• Diphenhydramine; Hydrocodone; Phenylephrine
• Diphenhydramine; Ibuprofen
• Diphenhydramine; Naproxen
• Diphenhydramine; Phenylephrine
• Dipyridamole
• Disulfiram
• Dobutamine
• Dolasetron
• Dopamine
• Doxepin
• Doxylamine
• Doxylamine; Pyridoxine
• Dronabinol
• Dronedarone
• Droperidol
• Drospirenone; Ethinyl Estradiol
• Drospirenone; Ethinyl Estradiol; Levomefolate
• Duloxetine
• Duvelisib
• Dyphylline
• Dyphylline; Guaifenesin
• Echinacea
• Efavirenz
• Efavirenz; Emtricitabine; Tenofovir
• Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
• Elagolix
• Elagolix; Estradiol; Norethindrone acetate
• Elbasvir; Grazoprevir
• Eletriptan
• Elexacaftor; tezacaftor; ivacaftor
• Eliglustat
• Eltrombopag
• Eluxadoline
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
• Enalapril; Hydrochlorothiazide, HCTZ
• Encorafenib
• Enflurane
• Enzalutamide
• Ephedrine
• Epinephrine
• Eprosartan; Hydrochlorothiazide, HCTZ
• Erythromycin
• Erythromycin; Sulfisoxazole
• Escitalopram
• Esketamine
• Eslicarbazepine
• Estazolam
• Eszopiclone
• Ethanol
• Ethinyl Estradiol
• Ethinyl Estradiol; Desogestrel
• Ethinyl Estradiol; Ethynodiol Diacetate
• Ethinyl Estradiol; Etonogestrel
• Ethinyl Estradiol; Levonorgestrel
• Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
• Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
• Ethinyl Estradiol; Norelgestromin
• Ethinyl Estradiol; Norethindrone
• Ethinyl Estradiol; Norethindrone Acetate
• Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
• Ethinyl Estradiol; Norethindrone; Ferrous fumarate
• Ethinyl Estradiol; Norgestimate
• Ethinyl Estradiol; Norgestrel
• Etomidate
• Etravirine
• Everolimus
• Exenatide
• Fedratinib
• Fesoterodine
• Fexofenadine; Pseudoephedrine
• Flavoxate
• Flibanserin
• Fluconazole
• Fluoxetine
• Fluoxetine; Olanzapine
• Fluphenazine
• Flurazepam
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• Fluvoxamine
• Formoterol
• Formoterol; Mometasone
• Fosamprenavir
• Fosinopril; Hydrochlorothiazide, HCTZ
• Fosphenytoin
• Fospropofol
• Fostamatinib
• Frovatriptan
• Gabapentin
• General anesthetics
• Givosiran
• Glycopyrrolate
• Glycopyrrolate; Formoterol
• Granisetron
• grapefruit juice
• Green Tea
• Guaifenesin; Hydrocodone
• Guaifenesin; Hydrocodone; Pseudoephedrine
• Guaifenesin; Phenylephrine
• Guaifenesin; Pseudoephedrine
• Guanabenz
• Guanfacine
• Halofantrine
• Haloperidol
• Halothane
• Homatropine; Hydrocodone
• Hydantoins
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone
• Hydrocodone; Ibuprofen
• Hydrocodone; Phenylephrine
• Hydrocodone; Potassium Guaiacolsulfonate
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydromorphone
• Hydroxyprogesterone
• Hydroxyzine
• Hyoscyamine
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibuprofen; Oxycodone
• Ibuprofen; Pseudoephedrine
• Idelalisib
• Imatinib
• Imipramine
• Indacaterol
• Indacaterol; Glycopyrrolate
• Indinavir
• Insulin Glargine; Lixisenatide
• Isavuconazonium
• Isocarboxazid
• Isoflurane
• Isoniazid, INH
• Isoniazid, INH; Pyrazinamide, PZA; Rifampin
• Isoniazid, INH; Rifampin
• Isoproterenol
• Istradefylline
• Itraconazole
• Ivacaftor
• Ketamine
• Ketoconazole
• Ketoprofen
• Lamivudine, 3TC; Zidovudine, ZDV
• Lamotrigine
• Lanthanum Carbonate
• Lapatinib
• Larotrectinib
• Lasmiditan
• Lefamulin
• Lemborexant
• Lesinurad
• Lesinurad; Allopurinol
• Letermovir
• Levalbuterol
• Levobupivacaine
• Levocetirizine
• Lidocaine
• Lidocaine; Prilocaine
• Lincosamides
• Linezolid
• Lisdexamfetamine
• Lithium
• Lixisenatide
• Lofexidine
• Lomitapide
• Loperamide
• Loperamide; Simethicone
• Lopinavir; Ritonavir
• Loratadine; Pseudoephedrine
• Lorazepam
• Lorcaserin
• Lorlatinib
• Loxapine
• Lumacaftor; Ivacaftor
• Lumacaftor; Ivacaftor
• Lumateperone
• Lurasidone
• Magnesium Salicylate
• Magnesium Salts
• Maprotiline
• Melatonin
• Mepenzolate
• Meperidine; Promethazine
• Mephobarbital
• Mepivacaine
• Mepivacaine; Levonordefrin
• Meprobamate
• Mestranol; Norethindrone
• Metaproterenol
• Metaxalone
• Methadone
• Methamphetamine
• Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
• Methocarbamol
• Methohexital
• Methscopolamine
• Methyclothiazide
• Methyldopa
• Methylene Blue
• Methylphenidate
• Metoclopramide
• Metolazone
• Metyrapone
• Metyrosine
• Mexiletine
• Midazolam
• Midodrine
• Mifepristone
• Minocycline
• Mipomersen
• Mirabegron
• Mirtazapine
• Mitotane
• Modafinil
• Molindone
• Monoamine oxidase inhibitors
• Morphine
• Morphine; Naltrexone
• Nabilone
• Nafcillin
• Nalbuphine
• Naloxone
• Naltrexone
• Naproxen; Pseudoephedrine
• Naproxen; Sumatriptan
• Naratriptan
• Nefazodone
• Nelfinavir
• Nesiritide, BNP
• Netupitant, Fosnetupitant; Palonosetron
• Nevirapine
• Nicardipine
• Nilotinib
• Nitroglycerin
• Non-Ionic Contrast Media
• Norepinephrine
• Nortriptyline
• Obeticholic Acid
• Octreotide
• Olanzapine
• Olodaterol
• Ombitasvir; Paritaprevir; Ritonavir
• Omeprazole; Amoxicillin; Rifabutin
• Omeprazole; Sodium Bicarbonate
• Ondansetron
• Oritavancin
• Orphenadrine
• Osilodrostat
• Oxazepam
• Oxcarbazepine
• Oxybutynin
• Oxycodone
• Oxymorphone
• Ozanimod
• Palbociclib
• Paliperidone
• Palonosetron
• Panobinostat
• Papaverine
• Paroxetine
• Pazopanib
• Peginterferon Alfa-2b
• Pegvisomant
• Pemoline
• Penicillin G Benzathine; Penicillin G Procaine
• Penicillin G Procaine
• Pentazocine
• Pentazocine; Naloxone
• Pentobarbital
• Perampanel
• Perindopril; Amlodipine
• Perphenazine
• Perphenazine; Amitriptyline
• Phendimetrazine
• Phenelzine
• Phenobarbital
• Phentermine
• Phentermine; Topiramate
• Phenylephrine
• Phenylephrine; Promethazine
• Phenytoin
• Pimozide
• Pirbuterol
• Pneumococcal Vaccine, Polyvalent
• Posaconazole
• Pramipexole
• Pramlintide
• Prasugrel
• Pregabalin
• Prilocaine
• Prilocaine; Epinephrine
• Primidone
• Procaine
• Procarbazine
• Prochlorperazine
• Promethazine
• Propafenone
• Propantheline
• Propofol
• Protriptyline
• Pseudoephedrine
• Quazepam
• Quetiapine
• Quinidine
• Quinine
• Racepinephrine
• Ramelteon
• Ranolazine
• Rasagiline
• Regadenoson
• Ribociclib
• Ribociclib; Letrozole
• Rifabutin
• Rifampin
• Rifamycins
• Rifapentine
• Rifaximin
• Risperidone
• Ritodrine
• Ritonavir
• Rizatriptan
• Rolapitant
• Ropinirole
• Ropivacaine
• Rotigotine
• Rucaparib
• Safinamide
• Salmeterol
• Salsalate
• Saquinavir
• Scopolamine
• Secobarbital
• Segesterone Acetate; Ethinyl Estradiol
• Selegiline
• Selpercatinib
• Serotonin-Receptor Agonists
• Serotonin-Receptor Antagonists
• Sertraline
• Sevoflurane
• Sildenafil
• Skeletal Muscle Relaxants
• Sodium Bicarbonate
• Sodium Oxybate
• Solifenacin
• Solriamfetol
• Spironolactone
• St. John’s Wort, Hypericum perforatum
• Streptogramins
• Sulfinpyrazone
• Sumatriptan
• Suvorexant
• Tapentadol
• Tasimelteon
• Telaprevir
• Telithromycin
• Telotristat Ethyl
• Temazepam
• Terbinafine
• Terbutaline
• Teriflunomide
• Tetrabenazine
• Tetracaine
• Tezacaftor; Ivacaftor
• Thalidomide
• Theophylline, Aminophylline
• Thiabendazole
• Thiazide diuretics
• Thiopental
• Thioridazine
• Thiothixene
• Ticagrelor
• Tiotropium; Olodaterol
• Tipranavir
• Tizanidine
• tobacco
• Tolterodine
• Topiramate
• Tramadol
• Trandolapril; Verapamil
• Tranylcypromine
• Trazodone
• Triazolam
• Tricyclic antidepressants
• Trifluoperazine
• Trihexyphenidyl
• Trimethobenzamide
• Trimetrexate
• Trimipramine
• Triprolidine
• Trospium
• Tucatinib
• Umeclidinium; Vilanterol
• Valerian, Valeriana officinalis
• Valproic Acid, Divalproex Sodium
• Vemurafenib
• Venlafaxine
• Verapamil
• Vigabatrin
• Vilazodone
• Voriconazole
• Vortioxetine
• Warfarin
• Yohimbine
• Zafirlukast
• Zaleplon
• Ziconotide
• Zidovudine, ZDV
• Zileuton
• Ziprasidone
• Zolmitriptan
• Zolpidem