Acetaminophen Butalbital Caffeine Codeine

Acetaminophen Butalbital Caffeine Codeine Brand Names

• Fioricet with Codeine
• Phrenilin with Caffeine and Codeine

What is Acetaminophen Butalbital Caffeine Codeine

AAcetaminophen Butalbital Caffeine Codeine are used together in an oral preparation to treat occasional tension headaches, migraines, and mild to moderate pain, especially when antianxiety or relaxant effects are needed.

Treatment of multiple recurrent headaches with this combination has not been well studied; long-term use is not recommended.

According to published guidelines for the acute management of migraine, the use of butalbital-containing analgesics should be limited and carefully monitored due to concerns of overuse, medication-overuse headache, and withdrawal

Indications

• headache
• migraine
• mild pain
• moderate pain

Side Effects

1. abdominal pain
2. acneiform rash
3. acute generalized exanthematous pustulosis (AGEP)
4. adrenocortical insufficiency
5. agitation
6. agranulocytosis
7. amenorrhea
8. anaphylactic shock
9. anaphylactoid reactions
10. angioedema
11. anorexia
12. anxiety
13. appetite stimulation
14. bleeding
15. chest pain (unspecified)
16. confusion
17. constipation
18. contact dermatitis
19. depression
20. diarrhea
21. dizziness
22. drowsiness
23. dysarthria
24. dyspepsia
25. dysphagia
26. dyspnea
27. edema
28. emotional lability
29. encephalopathy
30. epistaxis
31. erythema
32. erythema multiforme
33. esophagitis
34. euphoria
35. exfoliative dermatitis
36. fatigue
37. fever
38. flatulence
39. flushing
40. gonadal suppression
41. hallucinations
42. headache
43. hemolysis
44. hemolytic anemia
45. hepatic necrosis
46. hepatotoxicity
47. hiccups
48. hot flashes
49. hyperactivity
50. hyperglycemia
51. hyperhidrosis
52. hypersalivation
53. hyponatremia
54. hypotension
55. impotence (erectile dysfunction)
56. increased urinary frequency
57. infertility
58. insomnia
59. interstitial nephritis
60. irritability
61. jaundice
62. lethargy
63. libido decrease
64. libido increase
65. maculopapular rash
66. methemoglobinemia
67. miosis
68. musculoskeletal pain
69. nasal congestion
70. nausea
71. neonatal opioid withdrawal syndrome
72. otalgia
73. palpitations
74. pancytopenia
75. paresthesias
76. peptic ulcer
77. peripheral neuropathy
78. photosensitivity
79. physiological dependence
80. polyuria
81. pruritus
82. psychological dependence
83. psychosis
84. ptosis
85. purpura
86. rash
87. renal failure (unspecified)
88. renal papillary necrosis
89. renal tubular necrosis
90. respiratory arrest
91. respiratory depression
92. restlessness
93. seizures
94. serotonin syndrome
95. SIADH
96. sinus tachycardia
97. syncope
98. thrombocytopenia
99. thrombocytosis
100. tinnitus
101. tolerance
102. toxic epidermal necrolysis
103. tremor
104. urinary retention
105. urticaria
106. vertigo
107. vomiting
108. withdrawal
109. xerostomia

Monitoring Parameters

• LFTs
• serum creatinine/BUN: in chronic use or acute toxicity

Contraindications

• abrupt discontinuation
• accidental exposure
• acetaminophen hypersensitivity
• acute abdomen
• adenoidectomy
• adrenal insufficiency
• agranulocytosis
• alcoholism
• anemia
• anticoagulant therapy
• Asian patients
• asthma
• barbiturate hypersensitivity
• biliary tract disease
• Black patients
• bladder obstruction
• bone marrow suppression
• breast-feeding
• carbamazepine hypersensitivity
• cardiac disease
• Caucasian patients
• children
• chronic obstructive pulmonary disease (COPD)
• CNS depression
• coadministration with other CNS depressants
• constipation
• depression
• diabetes mellitus
• driving or operating machinery
• ethanol ingestion
• ethanol intoxication
• exfoliative dermatitis
• G6PD deficiency
• geriatric
• GI obstruction
• head trauma
• hepatic disease
• hepatic encephalopathy
• hepatitis
• hepatotoxicity
• Hispanic patients
• hydantoin hypersensitivity
• hypothyroidism
• ileus
• immunosuppression
• increased intracranial pressure
• infants
• infection
• labor
• MAOI therapy
• mental status changes
• myxedema
• neonatal opioid withdrawal syndrome
• neonates
• neuromuscular disease
• obesity
• obstetric delivery
• oliguria
• opiate agonist hypersensitivity
• osteomalacia
• osteoporosis
• pain
• porphyria
• potential for overdose or poisoning
• pregnancy
• prostatic hypertrophy
• pulmonary disease
• respiratory depression
• respiratory infection
• seizure disorder
• seizures
• sleep apnea
• status asthmaticus
• status epilepticus
• substance abuse
• suicidal ideation
• thyroid disease
• tonsillectomy
• urethral stricture
• urinary retention
• urinary tract obstruction

Interactions

• Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
• Abemaciclib
• Abiraterone
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital
• Acetaminophen; Butalbital; Caffeine
• Acetaminophen; Caffeine; Dihydrocodeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
• Acetaminophen; Dextromethorphan
• Acetaminophen; Dextromethorphan; Doxylamine
• Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
• Acetaminophen; Dextromethorphan; Phenylephrine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Dichloralphenazone; Isometheptene
• Acetaminophen; Diphenhydramine
• Acetaminophen; Guaifenesin; Phenylephrine
• Acetaminophen; Hydrocodone
• Acetaminophen; Oxycodone
• Acetaminophen; Pentazocine
• Acetaminophen; Pseudoephedrine
• Acetaminophen; Tramadol
• Acetazolamide
• Aclidinium; Formoterol
• Acrivastine; Pseudoephedrine
• Adenosine
• Albuterol
• Albuterol; Ipratropium
• Aldesleukin, IL-2
• Alfentanil
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Almotriptan
• Alosetron
• Alprazolam
• Altretamine
• Alvimopan
• Amantadine
• Amide local anesthetics
• Amifampridine
• Amiloride
• Amiloride; Hydrochlorothiazide, HCTZ
• Aminosalicylate sodium, Aminosalicylic acid
• Amiodarone
• Amitriptyline
• Amitriptyline; Chlordiazepoxide
• Amlodipine
• Amlodipine; Atorvastatin
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Amobarbital
• Amoxapine
• Amoxicillin; Clarithromycin; Lansoprazole
• Amoxicillin; Clarithromycin; Omeprazole
• Amphetamine
• Amphetamine; Dextroamphetamine
• Amphetamine; Dextroamphetamine Salts
• Amprenavir
• Anagrelide
• Antacids
• Anticholinergics
• Apalutamide
• Apomorphine
• Apraclonidine
• Apremilast
• Aprepitant, Fosaprepitant
• Arformoterol
• Aripiprazole
• Armodafinil
• Artemether; Lumefantrine
• Articaine; Epinephrine
• Asenapine
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atazanavir
• Atazanavir; Cobicistat
• Atenolol; Chlorthalidone
• Atorvastatin
• Atorvastatin; Ezetimibe
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Atropine; Hyoscyamine; Phenobarbital; Scopolamine
• Avanafil
• Avapritinib
• Avatrombopag
• Axitinib
• Azelastine
• Azelastine; Fluticasone
• Azilsartan; Chlorthalidone
• Baclofen
• Barbiturates
• Bedaquiline
• Belladonna Alkaloids; Ergotamine; Phenobarbital
• Belladonna; Opium
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendamustine
• Bendroflumethiazide; Nadolol
• Benzhydrocodone; Acetaminophen
• Benzodiazepines
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Benzonatate
• Benzphetamine
• Benztropine
• Beta-agonists
• Bethanechol
• Bexarotene
• Bicalutamide
• Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Boceprevir
• Bortezomib
• Bosentan
• Brexpiprazole
• Brigatinib
• Brimonidine
• Brimonidine; Brinzolamide
• Brimonidine; Timolol
• Brivaracetam
• Bromocriptine
• Brompheniramine
• Brompheniramine; Carbetapentane; Phenylephrine
• Brompheniramine; Dextromethorphan; Guaifenesin
• Brompheniramine; Guaifenesin; Hydrocodone
• Brompheniramine; Hydrocodone; Pseudoephedrine
• Brompheniramine; Pseudoephedrine
• Budesonide
• Budesonide; Formoterol
• Bumetanide
• Bupivacaine
• Bupivacaine Liposomal
• Bupivacaine; Lidocaine
• Buprenorphine
• Buprenorphine; Naloxone
• Bupropion
• Bupropion; Naltrexone
• Buspirone
• Busulfan
• Butabarbital
• Butorphanol
• Caffeine
• Calcifediol
• Calcitriol
• Candesartan; Hydrochlorothiazide, HCTZ
• Cannabidiol
• Capmatinib
• Capsaicin; Metaxalone
• Captopril; Hydrochlorothiazide, HCTZ
• Carbamazepine
• Carbetapentane; Chlorpheniramine
• Carbetapentane; Chlorpheniramine; Phenylephrine
• Carbetapentane; Diphenhydramine; Phenylephrine
• Carbetapentane; Guaifenesin
• Carbetapentane; Guaifenesin; Phenylephrine
• Carbetapentane; Phenylephrine
• Carbetapentane; Phenylephrine; Pyrilamine
• Carbetapentane; Pseudoephedrine
• Carbetapentane; Pyrilamine
• Carbidopa; Levodopa; Entacapone
• Carbinoxamine
• Carbinoxamine; Dextromethorphan; Pseudoephedrine
• Carbinoxamine; Hydrocodone; Phenylephrine
• Carbinoxamine; Hydrocodone; Pseudoephedrine
• Carbinoxamine; Phenylephrine
• Carbinoxamine; Pseudoephedrine
• Cardiac glycosides
• Cariprazine
• Carisoprodol
• Celecoxib
• Cenobamate
• Ceritinib
• Cetirizine
• Cetirizine; Pseudoephedrine
• Cevimeline
• Charcoal
• Chlophedianol; Dexbrompheniramine
• Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
• Chlophedianol; Guaifenesin; Phenylephrine
• Chloral Hydrate
• Chlorambucil
• Chloramphenicol
• Chlorcyclizine
• Chlordiazepoxide
• Chlordiazepoxide; Clidinium
• Chloroprocaine
• Chlorothiazide
• Chlorpheniramine
• Chlorpheniramine; Codeine
• Chlorpheniramine; Dextromethorphan
• Chlorpheniramine; Dextromethorphan; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
• Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Hydrocodone
• Chlorpheniramine; Hydrocodone; Phenylephrine
• Chlorpheniramine; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Phenylephrine
• Chlorpheniramine; Pseudoephedrine
• Chlorpromazine
• Chlorthalidone
• Chlorthalidone; Clonidine
• Chlorzoxazone
• Cholestyramine
• Choline Salicylate; Magnesium Salicylate
• Cimetidine
• Cinacalcet
• Ciprofloxacin
• Citalopram
• Clarithromycin
• Clemastine
• Clobazam
• Clomipramine
• Clonazepam
• Clonidine
• Clopidogrel
• Clorazepate
• Clozapine
• Cobicistat
• Cobimetinib
• Codeine; Phenylephrine; Promethazine
• Codeine; Promethazine
• COMT inhibitors
• Conivaptan
• Conjugated Estrogens
• Conjugated Estrogens; Bazedoxifene
• Conjugated Estrogens; Medroxyprogesterone
• Crizotinib
• Crofelemer
• Cyclizine
• Cyclobenzaprine
• Cyclophosphamide
• Cyclosporine
• Cyproheptadine
• Dabrafenib
• Dacomitinib
• Dalfopristin; Quinupristin
• Danazol
• Dantrolene
• Dapsone
• Darifenacin
• Darunavir
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
• Deflazacort
• Delavirdine
• Desflurane
• Desipramine
• Desloratadine; Pseudoephedrine
• Desmopressin
• Desvenlafaxine
• Deutetrabenazine
• Dexamethasone
• Dexchlorpheniramine
• Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
• Dexmedetomidine
• Dexmethylphenidate
• Dexpanthenol
• Dextroamphetamine
• Dextromethorphan
• Dextromethorphan; Diphenhydramine; Phenylephrine
• Dextromethorphan; Guaifenesin
• Dextromethorphan; Guaifenesin; Phenylephrine
• Dextromethorphan; Guaifenesin; Potassium Guaiacolsulfonate
• Dextromethorphan; Guaifenesin; Pseudoephedrine
• Dextromethorphan; Promethazine
• Dextromethorphan; Quinidine
• Diazepam
• Diclofenac
• Diclofenac; Misoprostol
• Dienogest; Estradiol valerate
• Diethylpropion
• Diethylstilbestrol, DES
• Diflunisal
• Dihydrocodeine; Guaifenesin; Pseudoephedrine
• Diltiazem
• Dimenhydrinate
• Diphenhydramine
• Diphenhydramine; Hydrocodone; Phenylephrine
• Diphenhydramine; Ibuprofen
• Diphenhydramine; Naproxen
• Diphenhydramine; Phenylephrine
• Dipyridamole
• Disopyramide
• Disulfiram
• Dobutamine
• Dolasetron
• Dolutegravir; Rilpivirine
• Donepezil
• Donepezil; Memantine
• Dopamine
• Doravirine
• Doravirine; Lamivudine; Tenofovir disoproxil fumarate
• Doxepin
• Doxercalciferol
• Doxorubicin
• Doxycycline
• Doxylamine
• Doxylamine; Pyridoxine
• Dronabinol
• Dronedarone
• Droperidol
• Drospirenone; Estradiol
• Drospirenone; Ethinyl Estradiol
• Drospirenone; Ethinyl Estradiol; Levomefolate
• Duloxetine
• Dyphylline
• Dyphylline; Guaifenesin
• Echinacea
• Efavirenz
• Efavirenz; Emtricitabine; Tenofovir
• Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
• Elagolix
• Elagolix; Estradiol; Norethindrone acetate
• Elbasvir; Grazoprevir
• Eletriptan
• Eliglustat
• Eltrombopag
• Eluxadoline
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
• Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
• Empagliflozin; Linagliptin
• Empagliflozin; Linagliptin; Metformin
• Emtricitabine; Rilpivirine; Tenofovir alafenamide
• Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Encorafenib
• Enflurane
• Entacapone
• Entrectinib
• Enzalutamide
• Ephedrine
• Epinephrine
• Eprosartan; Hydrochlorothiazide, HCTZ
• Erdafitinib
• Erlotinib
• Erythromycin
• Erythromycin; Sulfisoxazole
• Escitalopram
• Esketamine
• Eslicarbazepine
• Esomeprazole
• Esomeprazole; Naproxen
• Estazolam
• Esterified Estrogens
• Esterified Estrogens; Methyltestosterone
• Estradiol
• Estradiol Cypionate; Medroxyprogesterone
• Estradiol; Levonorgestrel
• Estradiol; Norethindrone
• Estradiol; Norgestimate
• Estradiol; Progesterone
• Estrogens
• Estropipate
• Eszopiclone
• Ethacrynic Acid
• Ethanol
• Ethinyl Estradiol
• Ethinyl Estradiol; Desogestrel
• Ethinyl Estradiol; Ethynodiol Diacetate
• Ethinyl Estradiol; Etonogestrel
• Ethinyl Estradiol; Levonorgestrel
• Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
• Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
• Ethinyl Estradiol; Norelgestromin
• Ethinyl Estradiol; Norethindrone
• Ethinyl Estradiol; Norethindrone Acetate
• Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
• Ethinyl Estradiol; Norethindrone; Ferrous fumarate
• Ethinyl Estradiol; Norgestimate
• Ethinyl Estradiol; Norgestrel
• Ethosuximide
• Ethotoin
• Etomidate
• Etravirine
• Everolimus
• Exenatide
• Ezetimibe; Simvastatin
• Fedratinib
• Felodipine
• Fenoprofen
• Fentanyl
• Fesoterodine
• Fexofenadine; Pseudoephedrine
• Flibanserin
• Fluconazole
• Fluoxetine
• Fluoxetine; Olanzapine
• Fluphenazine
• Flurazepam
• Fluticasone
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• Fluvoxamine
• food
• Formoterol
• Formoterol; Mometasone
• Fosamprenavir
• Fosinopril; Hydrochlorothiazide, HCTZ
• Fosphenytoin
• Fospropofol
• Fostamatinib
• Frovatriptan
• Furosemide
• Gabapentin
• Galantamine
• Gallium Ga 68 Dotatate
• General anesthetics
• Givosiran
• Glasdegib
• Glimepiride
• Glimepiride; Pioglitazone
• Glimepiride; Rosiglitazone
• Glycopyrrolate; Formoterol
• Granisetron
• grapefruit juice
• Green Tea
• Griseofulvin
• Guaifenesin; Hydrocodone
• Guaifenesin; Hydrocodone; Pseudoephedrine
• Guaifenesin; Phenylephrine
• Guaifenesin; Pseudoephedrine
• Guanabenz
• Guanfacine
• Haloperidol
• Halothane
• Hemin
• Homatropine; Hydrocodone
• Hydantoins
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone
• Hydrocodone; Ibuprofen
• Hydrocodone; Phenylephrine
• Hydrocodone; Potassium Guaiacolsulfonate
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydromorphone
• Hydroxyprogesterone
• Hydroxyzine
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibuprofen; Oxycodone
• Ibuprofen; Pseudoephedrine
• Idelalisib
• Ifosfamide
• Iloperidone
• Imatinib
• Imipramine
• Indacaterol
• Indacaterol; Glycopyrrolate
• Indapamide
• Indinavir
• Insulin Glargine; Lixisenatide
• Isavuconazonium
• Isocarboxazid
• Isoflurane
• Isoniazid, INH
• Isoniazid, INH; Pyrazinamide, PZA; Rifampin
• Isoniazid, INH; Rifampin
• Isoproterenol
• Isradipine
• Istradefylline
• Itraconazole
• Ivabradine
• Ixabepilone
• Ketamine
• Ketoconazole
• Ketoprofen
• Lamivudine, 3TC; Zidovudine, ZDV
• Lamotrigine
• Lansoprazole
• Lansoprazole; Naproxen
• Lanthanum Carbonate
• Lapatinib
• Larotrectinib
• Lasmiditan
• Lefamulin
• Lemborexant
• Lesinurad
• Lesinurad; Allopurinol
• Letermovir
• Leucovorin
• Levalbuterol
• Levobupivacaine
• Levocetirizine
• Levoleucovorin
• Levomilnacipran
• Levorphanol
• Lidocaine
• Lidocaine; Prilocaine
• Linagliptin
• Linagliptin; Metformin
• Lincosamides
• Linezolid
• Lisdexamfetamine
• Lithium
• Lixisenatide
• Lofexidine
• Lomitapide
• Loop diuretics
• Loperamide
• Loperamide; Simethicone
• Lopinavir; Ritonavir
• Loratadine; Pseudoephedrine
• Lorazepam
• Lorlatinib
• Lovastatin
• Lovastatin; Niacin
• Loxapine
• Lumacaftor; Ivacaftor
• Lumateperone
• Lurasidone
• Magnesium Salicylate
• Magnesium Salts
• Mannitol
• Maprotiline
• Mebendazole
• Meclizine
• Mefloquine
• Melatonin
• Meperidine
• Meperidine; Promethazine
• Mephobarbital
• Mepivacaine
• Mepivacaine; Levonordefrin
• Meprobamate
• Mestranol; Norethindrone
• Metaproterenol
• Metaxalone
• Metformin; Repaglinide
• Methadone
• Methamphetamine
• Methazolamide
• Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
• Methocarbamol
• Methohexital
• Methscopolamine
• Methsuximide
• Methyclothiazide
• Methyldopa
• Methylene Blue
• Methylphenidate
• Methylprednisolone
• Metoclopramide
• Metolazone
• Metronidazole
• Metyrapone
• Metyrosine
• Mexiletine
• Midazolam
• Midodrine
• Mifepristone
• Milnacipran
• Minocycline
• Mipomersen
• Mirabegron
• Mirtazapine
• Mitotane
• Modafinil
• Molindone
• Monoamine oxidase inhibitors
• Morphine
• Morphine; Naltrexone
• Nabilone
• Nafcillin
• Nalbuphine
• Naloxone
• Naltrexone
• Nanoparticle Albumin-Bound Paclitaxel
• Naproxen; Pseudoephedrine
• Naproxen; Sumatriptan
• Naratriptan
• Nefazodone
• Nelfinavir
• Neratinib
• Nesiritide, BNP
• Netupitant, Fosnetupitant; Palonosetron
• Nevirapine
• Niacin; Simvastatin
• Nicardipine
• Nifedipine
• Nilotinib
• Nimodipine
• Nintedanib
• Nisoldipine
• Nitroglycerin
• Non-Ionic Contrast Media
• Norepinephrine
• Nortriptyline
• Obeticholic Acid
• Octreotide
• Olanzapine
• Olaparib
• Olodaterol
• Ombitasvir; Paritaprevir; Ritonavir
• Omeprazole
• Omeprazole; Amoxicillin; Rifabutin
• Omeprazole; Sodium Bicarbonate
• Ondansetron
• Oritavancin
• Orphenadrine
• Osilodrostat
• Oxazepam
• Oxybutynin
• Oxycodone
• Oxymorphone
• Ozanimod
• Paclitaxel
• Palbociclib
• Paliperidone
• Palonosetron
• Panobinostat
• Papaverine
• Paroxetine
• Peginterferon Alfa-2b
• Pegvisomant
• Pemigatinib
• Pemoline
• Penicillin G Benzathine; Penicillin G Procaine
• Penicillin G Procaine
• Pentazocine
• Pentazocine; Naloxone
• Pentobarbital
• Perampanel
• Perindopril; Amlodipine
• Perphenazine
• Perphenazine; Amitriptyline
• Phendimetrazine
• Phenelzine
• Phenobarbital
• Phenothiazines
• Phentermine
• Phentermine; Topiramate
• Phenylephrine
• Phenylephrine; Promethazine
• Phenytoin
• Pimavanserin
• Pimozide
• Pirbuterol
• Pneumococcal Vaccine, Polyvalent
• Pomalidomide
• Posaconazole
• Potassium-sparing diuretics
• Pralidoxime
• Pramipexole
• Pramlintide
• Prasugrel
• Prednisolone
• Prednisone
• Pregabalin
• Prilocaine
• Prilocaine; Epinephrine
• Primidone
• Procarbazine
• Prochlorperazine
• Progestins
• Promethazine
• Propafenone
• Propofol
• Protriptyline
• Pseudoephedrine
• Quazepam
• Quetiapine
• Quinidine
• Quinine
• Rabeprazole
• Racepinephrine
• Ramelteon
• Ranolazine
• Rasagiline
• Red Yeast Rice
• Regadenoson
• Remifentanil
• Repaglinide
• Reserpine
• Ribociclib
• Ribociclib; Letrozole
• Rifabutin
• Rifampin
• Rifapentine
• Rifaximin
• Rilpivirine
• Riluzole
• Rimegepant
• Risperidone
• Ritodrine
• Ritonavir
• Rizatriptan
• Roflumilast
• Rolapitant
• Romidepsin
• Ropinirole
• Ropivacaine
• Rotigotine
• Rucaparib
• Safinamide
• Salicylates
• Salmeterol
• Salsalate
• Saquinavir
• Scopolamine
• Secobarbital
• Segesterone Acetate; Ethinyl Estradiol
• Selegiline
• Selpercatinib
• Selumetinib
• Serotonin-Receptor Agonists
• Serotonin-Receptor Antagonists
• Sertraline
• Sevoflurane
• Sildenafil
• Simvastatin
• Simvastatin; Sitagliptin
• Siponimod
• Sirolimus
• Skeletal Muscle Relaxants
• Sodium Bicarbonate
• Sodium Oxybate
• Solifenacin
• Solriamfetol
• Spironolactone
• St. John’s Wort, Hypericum perforatum
• Streptogramins
• Sufentanil
• Sulfinpyrazone
• Sumatriptan
• Sunitinib
• Suvorexant
• Tacrolimus
• Tapentadol
• Tasimelteon
• Tazemetostat
• Telaprevir
• Telithromycin
• Telotristat Ethyl
• Temazepam
• Terbinafine
• Terbutaline
• Teriflunomide
• Tetrabenazine
• Tetracaine
• Thalidomide
• Theophylline, Aminophylline
• Thiabendazole
• Thiazide diuretics
• Thiopental
• Thioridazine
• Thiothixene
• Thyroid hormones
• Ticagrelor
• Tiotropium; Olodaterol
• Tipranavir
• Tizanidine
• tobacco
• Tolcapone
• Tolterodine
• Topiramate
• Torsemide
• Tramadol
• Trandolapril; Verapamil
• Tranylcypromine
• Trazodone
• Tretinoin, ATRA
• Triamcinolone
• Triamterene
• Triazolam
• Tricyclic antidepressants
• Trifluoperazine
• Trimethobenzamide
• Trimetrexate
• Trimipramine
• Triprolidine
• Trospium
• Tucatinib
• Ubrogepant
• Ulipristal
• Umeclidinium; Vilanterol
• Valbenazine
• Valerian, Valeriana officinalis
• Valproic Acid, Divalproex Sodium
• Vemurafenib
• Venlafaxine
• Verapamil
• Vigabatrin
• Vilazodone
• Vincristine
• Vincristine Liposomal
• Vorapaxar
• Voriconazole
• Vortioxetine
• Voxelotor
• Warfarin
• Yohimbine
• Zaleplon
• Zanubrutinib
• Ziconotide
• Zidovudine, ZDV
• Zileuton
• Ziprasidone
• Zolmitriptan
• Zolpidem
• Zonisamide