Acetaminophen Butalbital Caffeine

Acetaminophen Butalbital Caffeine Brand Names

Alagesic | Alagesic LQ | Americet | Anolor-300 | Arcet | BAC | CAPACET | Dolgic LQ | Dolgic Plus | Esgic | Esgic Plus | Ezol | Fioricet | Geone | Margesic | Medigesic | Orbivan | Pacaps | Phrenilin Forte | Repan | Tenake | Triad | Vanatol LQ | Vanatol S | Vtol LQ | Zebutal

What is Acetaminophen Butalbital Caffeine

Acetaminophen, butalbital, and caffeine are used together in an oral preparation to treat tension headaches, migraines, and mild to moderate pain in adult and pediatric patients 12 years and older, especially when antianxiety or relaxant effects are needed.

Acetaminophen is a non-salicylate analgesic, butalbital is a barbiturate, and caffeine is a methylxanthine CNS psychostimulant.

Treatment of multiple recurrent headaches with this combination has not been well studied and extended use of these products is not recommended. 

Indications

• headache
• migraine

NOTE: The FDA has advised healthcare professionals to discontinue prescribing and dispensing of combination prescription medications containing > 325 mg acetaminophen per dosage unit.

This action has been taken to reduce the risk of liver damage and severe hypersensitivity reactions associated with acetaminophen.

For the treatment of the symptom complex of tension headache or occasional migraine

Side Effects

1. abdominal pain
2. acneiform rash
3. acute generalized exanthematous pustulosis (AGEP)
4. agitation
5. agranulocytosis
6. anaphylactoid reactions
7. angioedema
8. anorexia
9. anxiety
10. confusion
11. constipation
12. contact dermatitis
13. depression
14. dizziness
15. drowsiness
16. dyspepsia
17. dysphagia
18. dyspnea
19. edema
20. elevated hepatic enzymes
21. encephalopathy
22. erythema
23. erythema multiforme
24. euphoria
25. exfoliative dermatitis
26. fatigue
27. fever
28. flatulence
29. headache
30. hemolysis
31. hemolytic anemia
32. hepatic necrosis
33. hot flashes
34. hyperglycemia
35. hyperhidrosis
36. hypoprothrombinemia
37. increased urinary frequency
38. insomnia
39. interstitial nephritis
40. irritability
41. jaundice
42. lethargy
43. maculopapular rash
44. methemoglobinemia
45. musculoskeletal pain
46. nasal congestion
47. nausea
48. neutropenia
49. otalgia
50. palpitations
51. pancytopenia
52. paresthesias
53. photosensitivity
54. physiological dependence
55. polyuria
56. pruritus
57. psychological dependence
58. ptosis
59. purpura
60. rash
61. renal failure (unspecified)
62. renal papillary necrosis
63. renal tubular necrosis
64. seizures
65. sinus tachycardia
66. syncope
67. thrombocytopenia
68. thrombocytosis
69. tinnitus
70. tolerance
71. toxic epidermal necrolysis
72. tremor
73. urticaria
74. vertigo
75. vomiting
76. withdrawal
77. xerostomia

Monitoring Parameters

• LFTs
• serum creatinine/BUN: in chronic use or acute toxicity

Contraindications

• abrupt discontinuation
• acetaminophen hypersensitivity
• acute abdomen
• agranulocytosis
• alcoholism
• barbiturate hypersensitivity
• breast-feeding
• carbamazepine hypersensitivity
• cardiac disease
• children
• chronic obstructive pulmonary disease (COPD)
• CNS depression
• coadministration with other CNS depressants
• depression
• driving or operating machinery
• ethanol ingestion
• ethanol intoxication
• G6PD deficiency
• geriatric
• head trauma
• hepatic disease
• hepatitis
• hepatotoxicity
• hydantoin hypersensitivity
• hypovolemia
• infants
• malnutrition
• neonates
• porphyria
• potential for overdose or poisoning
• pregnancy
• pulmonary disease
• renal failure
• renal impairment
• respiratory depression
• seizure disorder
• sleep apnea
• substance abuse
• suicidal ideation
• tachycardia

Interactions

• Abacavir; Lamivudine, 3TC; Zidovudine, ZDV
• Abemaciclib
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital
• Acetaminophen; Butalbital; Caffeine; Codeine
• Acetaminophen; Caffeine; Dihydrocodeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
• Acetaminophen; Codeine
• Acetaminophen; Dextromethorphan; Doxylamine
• Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
• Acetaminophen; Dextromethorphan; Phenylephrine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Dichloralphenazone; Isometheptene
• Acetaminophen; Diphenhydramine
• Acetaminophen; Guaifenesin; Phenylephrine
• Acetaminophen; Hydrocodone
• Acetaminophen; Oxycodone
• Acetaminophen; Pentazocine
• Acetaminophen; Pseudoephedrine
• Acetaminophen; Tramadol
• Acetazolamide
• Aclidinium; Formoterol
• Acrivastine; Pseudoephedrine
• Adenosine
• Albuterol
• Albuterol; Ipratropium
• Aldesleukin, IL-2
• Alfentanil
• Aliskiren; Amlodipine
• Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
• Aliskiren; Hydrochlorothiazide, HCTZ
• Alprazolam
• Altretamine
• Amantadine
• Amiloride; Hydrochlorothiazide, HCTZ
• Aminosalicylate sodium, Aminosalicylic acid
• Amiodarone
• Amitriptyline; Chlordiazepoxide
• Amlodipine
• Amlodipine; Atorvastatin
• Amlodipine; Benazepril
• Amlodipine; Celecoxib
• Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
• Amlodipine; Olmesartan
• Amlodipine; Telmisartan
• Amlodipine; Valsartan
• Amobarbital
• Amoxapine
• Amoxicillin; Clarithromycin; Lansoprazole
• Amoxicillin; Clarithromycin; Omeprazole
• Amphetamine
• Amphetamine; Dextroamphetamine
• Amphetamine; Dextroamphetamine Salts
• Amprenavir
• Anagrelide
• Antacids
• Apomorphine
• Apraclonidine
• Apremilast
• Aprepitant, Fosaprepitant
• Arformoterol
• Aripiprazole
• Armodafinil
• Artemether; Lumefantrine
• Articaine; Epinephrine
• Asenapine
• Aspirin, ASA
• Aspirin, ASA; Butalbital; Caffeine
• Aspirin, ASA; Butalbital; Caffeine; Codeine
• Aspirin, ASA; Caffeine; Dihydrocodeine
• Aspirin, ASA; Caffeine; Orphenadrine
• Aspirin, ASA; Carisoprodol
• Aspirin, ASA; Carisoprodol; Codeine
• Aspirin, ASA; Citric Acid; Sodium Bicarbonate
• Aspirin, ASA; Dipyridamole
• Aspirin, ASA; Omeprazole
• Aspirin, ASA; Oxycodone
• Aspirin, ASA; Pravastatin
• Atazanavir
• Atazanavir; Cobicistat
• Atenolol; Chlorthalidone
• Atorvastatin
• Atorvastatin; Ezetimibe
• Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Atropine; Difenoxin
• Atropine; Diphenoxylate
• Atropine; Hyoscyamine; Phenobarbital; Scopolamine
• Avanafil
• Avapritinib
• Avatrombopag
• Axitinib
• Azelastine
• Azelastine; Fluticasone
• Azilsartan; Chlorthalidone
• Barbiturates
• Bedaquiline
• Belladonna Alkaloids; Ergotamine; Phenobarbital
• Belladonna; Opium
• Benazepril; Hydrochlorothiazide, HCTZ
• Bendamustine
• Bendroflumethiazide; Nadolol
• Benzhydrocodone; Acetaminophen
• Benzodiazepines
• Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
• Benzphetamine
• Benztropine
• Beta-agonists
• Bicalutamide
• Bismuth Subcitrate Potassium; Metronidazole; Tetracycline
• Bismuth Subsalicylate
• Bismuth Subsalicylate; Metronidazole; Tetracycline
• Bisoprolol; Hydrochlorothiazide, HCTZ
• Boceprevir
• Bortezomib
• Brexpiprazole
• Brigatinib
• Brimonidine
• Brimonidine; Brinzolamide
• Brimonidine; Timolol
• Brivaracetam
• Bromocriptine
• Brompheniramine
• Brompheniramine; Carbetapentane; Phenylephrine
• Brompheniramine; Dextromethorphan; Guaifenesin
• Brompheniramine; Guaifenesin; Hydrocodone
• Brompheniramine; Hydrocodone; Pseudoephedrine
• Brompheniramine; Pseudoephedrine
• Budesonide
• Budesonide; Formoterol
• Bupivacaine
• Bupivacaine Liposomal
• Bupivacaine; Lidocaine
• Buprenorphine
• Buprenorphine; Naloxone
• Bupropion
• Bupropion; Naltrexone
• Buspirone
• Busulfan
• Butabarbital
• Butorphanol
• Caffeine
• Calcifediol
• Calcitriol
• Candesartan; Hydrochlorothiazide, HCTZ
• Cannabidiol
• Capmatinib
• Captopril; Hydrochlorothiazide, HCTZ
• Carbamazepine
• Carbetapentane; Chlorpheniramine
• Carbetapentane; Chlorpheniramine; Phenylephrine
• Carbetapentane; Diphenhydramine; Phenylephrine
• Carbetapentane; Guaifenesin
• Carbetapentane; Guaifenesin; Phenylephrine
• Carbetapentane; Phenylephrine
• Carbetapentane; Phenylephrine; Pyrilamine
• Carbetapentane; Pseudoephedrine
• Carbetapentane; Pyrilamine
• Carbidopa; Levodopa; Entacapone
• Carbinoxamine
• Carbinoxamine; Dextromethorphan; Pseudoephedrine
• Carbinoxamine; Hydrocodone; Phenylephrine
• Carbinoxamine; Hydrocodone; Pseudoephedrine
• Carbinoxamine; Phenylephrine
• Carbinoxamine; Pseudoephedrine
• Cardiac glycosides
• Cariprazine
• Cenobamate
• Cetirizine
• Cetirizine; Pseudoephedrine
• Cevimeline
• Charcoal
• Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
• Chlophedianol; Guaifenesin; Phenylephrine
• Chlorambucil
• Chloramphenicol
• Chlordiazepoxide
• Chlordiazepoxide; Clidinium
• Chloroprocaine
• Chlorothiazide
• Chlorpheniramine
• Chlorpheniramine; Codeine
• Chlorpheniramine; Dextromethorphan
• Chlorpheniramine; Dextromethorphan; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Phenylephrine
• Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
• Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Hydrocodone
• Chlorpheniramine; Hydrocodone; Phenylephrine
• Chlorpheniramine; Hydrocodone; Pseudoephedrine
• Chlorpheniramine; Phenylephrine
• Chlorpheniramine; Pseudoephedrine
• Chlorthalidone
• Chlorthalidone; Clonidine
• Cholestyramine
• Choline Salicylate; Magnesium Salicylate
• Cimetidine
• Cinacalcet
• Ciprofloxacin
• Citalopram
• Clemastine
• Clobazam
• Clonazepam
• Clorazepate
• Clozapine
• Cobimetinib
• Codeine
• Codeine; Guaifenesin
• Codeine; Phenylephrine; Promethazine
• Codeine; Promethazine
• COMT inhibitors
• Conjugated Estrogens
• Conjugated Estrogens; Bazedoxifene
• Conjugated Estrogens; Medroxyprogesterone
• Cyclophosphamide
• Cyclosporine
• Cyproheptadine
• Dapsone
• Darifenacin
• Darunavir
• Darunavir; Cobicistat
• Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
• Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
• Deflazacort
• Delavirdine
• Desloratadine; Pseudoephedrine
• Deutetrabenazine
• Dexamethasone
• Dexchlorpheniramine
• Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
• Dexmedetomidine
• Dexmethylphenidate
• Dextroamphetamine
• Dextromethorphan; Diphenhydramine; Phenylephrine
• Dextromethorphan; Guaifenesin; Phenylephrine
• Dextromethorphan; Guaifenesin; Pseudoephedrine
• Dextromethorphan; Quinidine
• Diazepam
• Diclofenac
• Diclofenac; Misoprostol
• Dienogest; Estradiol valerate
• Diethylpropion
• Diethylstilbestrol, DES
• Diflunisal
• Dihydrocodeine; Guaifenesin; Pseudoephedrine
• Diltiazem
• Dimenhydrinate
• Diphenhydramine
• Diphenhydramine; Hydrocodone; Phenylephrine
• Diphenhydramine; Ibuprofen
• Diphenhydramine; Naproxen
• Diphenhydramine; Phenylephrine
• Dipyridamole
• Disopyramide
• Disulfiram
• Dobutamine
• Dolutegravir; Rilpivirine
• Donepezil
• Donepezil; Memantine
• Dopamine
• Doravirine
• Doravirine; Lamivudine; Tenofovir disoproxil fumarate
• Doxercalciferol
• Doxorubicin
• Doxycycline
• Doxylamine
• Doxylamine; Pyridoxine
• Dronabinol
• Dronedarone
• Droperidol
• Drospirenone; Estradiol
• Drospirenone; Ethinyl Estradiol
• Drospirenone; Ethinyl Estradiol; Levomefolate
• Dyphylline
• Dyphylline; Guaifenesin
• Echinacea
• Efavirenz
• Efavirenz; Emtricitabine; Tenofovir
• Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
• Elagolix; Estradiol; Norethindrone acetate
• Elbasvir; Grazoprevir
• Eltrombopag
• Empagliflozin; Linagliptin
• Empagliflozin; Linagliptin; Metformin
• Emtricitabine; Rilpivirine; Tenofovir alafenamide
• Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Encorafenib
• Entacapone
• Entrectinib
• Ephedrine
• Epinephrine
• Eprosartan; Hydrochlorothiazide, HCTZ
• Erdafitinib
• Erlotinib
• Erythromycin
• Erythromycin; Sulfisoxazole
• Escitalopram
• Esketamine
• Eslicarbazepine
• Esomeprazole
• Esomeprazole; Naproxen
• Estazolam
• Esterified Estrogens
• Esterified Estrogens; Methyltestosterone
• Estradiol
• Estradiol Cypionate; Medroxyprogesterone
• Estradiol; Levonorgestrel
• Estradiol; Norethindrone
• Estradiol; Norgestimate
• Estradiol; Progesterone
• Estrogens
• Estropipate
• Eszopiclone
• Ethanol
• Ethinyl Estradiol
• Ethinyl Estradiol; Desogestrel
• Ethinyl Estradiol; Ethynodiol Diacetate
• Ethinyl Estradiol; Etonogestrel
• Ethinyl Estradiol; Levonorgestrel
• Ethinyl Estradiol; Levonorgestrel; Ferrous bisglycinate
• Ethinyl Estradiol; Levonorgestrel; Folic Acid; Levomefolate
• Ethinyl Estradiol; Norelgestromin
• Ethinyl Estradiol; Norethindrone
• Ethinyl Estradiol; Norethindrone Acetate
• Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
• Ethinyl Estradiol; Norethindrone; Ferrous fumarate
• Ethinyl Estradiol; Norgestimate
• Ethinyl Estradiol; Norgestrel
• Ethosuximide
• Exenatide
• Ezetimibe; Simvastatin
• Fedratinib
• Felodipine
• Fenoprofen
• Fentanyl
• Fesoterodine
• Fexofenadine; Pseudoephedrine
• Flibanserin
• Fluconazole
• Fluoxetine; Olanzapine
• Fluticasone
• Fluticasone; Salmeterol
• Fluticasone; Umeclidinium; Vilanterol
• Fluticasone; Vilanterol
• Fluvoxamine
• food
• Formoterol
• Formoterol; Mometasone
• Fosamprenavir
• Fosinopril; Hydrochlorothiazide, HCTZ
• Gabapentin
• Galantamine
• Gallium Ga 68 Dotatate
• General anesthetics
• Givosiran
• Glasdegib
• Glimepiride
• Glimepiride; Pioglitazone
• Glimepiride; Rosiglitazone
• Glycopyrrolate; Formoterol
• grapefruit juice
• Green Tea
• Griseofulvin
• Guaifenesin; Hydrocodone
• Guaifenesin; Hydrocodone; Pseudoephedrine
• Guaifenesin; Phenylephrine
• Guaifenesin; Pseudoephedrine
• Guanfacine
• Haloperidol
• Hemin
• Homatropine; Hydrocodone
• Hydantoins
• Hydralazine; Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ
• Hydrochlorothiazide, HCTZ; Irbesartan
• Hydrochlorothiazide, HCTZ; Lisinopril
• Hydrochlorothiazide, HCTZ; Losartan
• Hydrochlorothiazide, HCTZ; Methyldopa
• Hydrochlorothiazide, HCTZ; Metoprolol
• Hydrochlorothiazide, HCTZ; Moexipril
• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone
• Hydrocodone; Ibuprofen
• Hydrocodone; Phenylephrine
• Hydrocodone; Potassium Guaiacolsulfonate
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydromorphone
• Hydroxyprogesterone
• Hydroxyzine
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
• Ibuprofen; Oxycodone
• Ibuprofen; Pseudoephedrine
• Ifosfamide
• Iloperidone
• Imatinib
• Indacaterol
• Indacaterol; Glycopyrrolate
• Indinavir
• Insulin Glargine; Lixisenatide
• Isavuconazonium
• Isocarboxazid
• Isoniazid, INH
• Isoniazid, INH; Pyrazinamide, PZA; Rifampin
• Isoniazid, INH; Rifampin
• Isoproterenol
• Isradipine
• Itraconazole
• Ivabradine
• Ixabepilone
• Ketoconazole
• Ketoprofen
• Lamivudine, 3TC; Zidovudine, ZDV
• Lamotrigine
• Lansoprazole
• Lansoprazole; Naproxen
• Lanthanum Carbonate
• Lasmiditan
• Lefamulin
• Lemborexant
• Lesinurad
• Lesinurad; Allopurinol
• Leucovorin
• Levalbuterol
• Levobupivacaine
• Levocetirizine
• Levoleucovorin
• Levorphanol
• Lidocaine
• Lidocaine; Prilocaine
• Linagliptin
• Linagliptin; Metformin
• Linezolid
• Lisdexamfetamine
• Lithium
• Lixisenatide
• Lofexidine
• Lomitapide
• Lopinavir; Ritonavir
• Loratadine; Pseudoephedrine
• Lorazepam
• Lorlatinib
• Lovastatin
• Lovastatin; Niacin
• Loxapine
• Lumateperone
• Lurasidone
• Magnesium Salicylate
• Magnesium Salts
• Mannitol
• Maprotiline
• Mebendazole
• Meclizine
• Mefloquine
• Melatonin
• Meperidine
• Meperidine; Promethazine
• Mephobarbital
• Mepivacaine
• Mepivacaine; Levonordefrin
• Meprobamate
• Mestranol; Norethindrone
• Metaproterenol
• Metformin; Repaglinide
• Methadone
• Methamphetamine
• Methazolamide
• Methocarbamol
• Methohexital
• Methscopolamine
• Methsuximide
• Methyclothiazide
• Methylphenidate
• Methylprednisolone
• Metoclopramide
• Metolazone
• Metronidazole
• Metyrapone
• Metyrosine
• Mexiletine
• Midazolam
• Midodrine
• Minocycline
• Mipomersen
• Mirtazapine
• Mitotane
• Modafinil
• Monoamine oxidase inhibitors
• Morphine
• Morphine; Naltrexone
• Nabilone
• Nalbuphine
• Nanoparticle Albumin-Bound Paclitaxel
• Naproxen; Pseudoephedrine
• Nelfinavir
• Neratinib
• Nevirapine
• Niacin; Simvastatin
• Nicardipine
• Nifedipine
• Nimodipine
• Nintedanib
• Nisoldipine
• Non-Ionic Contrast Media
• Norepinephrine
• Obeticholic Acid
• Olanzapine
• Olaparib
• Olodaterol
• Ombitasvir; Paritaprevir; Ritonavir
• Omeprazole
• Omeprazole; Amoxicillin; Rifabutin
• Omeprazole; Sodium Bicarbonate
• Ondansetron
• Oxazepam
• Oxybutynin
• Oxycodone
• Oxymorphone
• Paclitaxel
• Paliperidone
• Papaverine
• Paroxetine
• Peginterferon Alfa-2b
• Pemigatinib
• Pemoline
• Penicillin G Benzathine; Penicillin G Procaine
• Penicillin G Procaine
• Pentazocine
• Pentazocine; Naloxone
• Pentobarbital
• Perampanel
• Perindopril; Amlodipine
• Phendimetrazine
• Phenelzine
• Phenobarbital
• Phenothiazines
• Phentermine
• Phentermine; Topiramate
• Phenylephrine
• Phenylephrine; Promethazine
• Pimavanserin
• Pirbuterol
• Pneumococcal Vaccine, Polyvalent
• Pomalidomide
• Posaconazole
• Pralidoxime
• Pramipexole
• Pramlintide
• Prednisolone
• Prednisone
• Pregabalin
• Prilocaine
• Prilocaine; Epinephrine
• Primidone
• Procarbazine
• Progestins
• Pseudoephedrine
• Quazepam
• Quetiapine
• Quinidine
• Quinine
• Rabeprazole
• Racepinephrine
• Ramelteon
• Ranolazine
• Rasagiline
• Red Yeast Rice
• Regadenoson
• Remifentanil
• Repaglinide
• Reserpine
• Rifabutin
• Rifampin
• Rifapentine
• Rilpivirine
• Riluzole
• Rimegepant
• Risperidone
• Ritodrine
• Ritonavir
• Roflumilast
• Romidepsin
• Ropinirole
• Ropivacaine
• Rotigotine
• Rucaparib
• Safinamide
• Salicylates
• Salmeterol
• Salsalate
• Saquinavir
• Scopolamine
• Secobarbital
• Segesterone Acetate; Ethinyl Estradiol
• Selegiline
• Selpercatinib
• Selumetinib
• Sertraline
• Sildenafil
• Simvastatin
• Simvastatin; Sitagliptin
• Siponimod
• Sirolimus
• Skeletal Muscle Relaxants
• Sodium Bicarbonate
• Sodium Oxybate
• Solifenacin
• Solriamfetol
• Spironolactone
• St. John’s Wort, Hypericum perforatum
• Sufentanil
• Sulfinpyrazone
• Sunitinib
• Suvorexant
• Tacrolimus
• Tapentadol
• Tasimelteon
• Tazemetostat
• Telaprevir
• Telotristat Ethyl
• Temazepam
• Terbinafine
• Terbutaline
• Teriflunomide
• Tetrabenazine
• Tetracaine
• Thalidomide
• Theophylline, Aminophylline
• Thiabendazole
• Thiazide diuretics
• Thiopental
• Thiothixene
• Thyroid hormones
• Tiotropium; Olodaterol
• Tipranavir
• Tizanidine
• tobacco
• Tolcapone
• Tolterodine
• Topiramate
• Tramadol
• Trandolapril; Verapamil
• Tranylcypromine
• Trazodone
• Tretinoin, ATRA
• Triamcinolone
• Triazolam
• Tricyclic antidepressants
• Trimethobenzamide
• Trimetrexate
• Triprolidine
• Ubrogepant
• Ulipristal
• Umeclidinium; Vilanterol
• Valbenazine
• Valerian, Valeriana officinalis
• Valproic Acid, Divalproex Sodium
• Vemurafenib
• Verapamil
• Vigabatrin
• Vincristine
• Vincristine Liposomal
• Vorapaxar
• Voriconazole
• Vortioxetine
• Voxelotor
• Warfarin
• Yohimbine
• Zaleplon
• Zanubrutinib
• Ziconotide
• Zidovudine, ZDV
• Zileuton
• Ziprasidone
• Zolmitriptan
• Zolpidem
• Zonisamide