What is Telithromycin Telithromycin (HMR 3647) is a broad-spectrum antibiotic and the first in a family called ‘ketolides’. Chemically, ketolides resemble macrolides, however, telithromycin exhibits greater antibacterial killing than macrolides. Telithromycin has been studied in multiple types of respiratory tract infections and its spectrum of activity is good against respiratory pathogens including erythromycin- and penicillin-resistant …
What is Telbivudine Telbivudine is a synthetic thymidine nucleoside analogue with activity against hepatitis B virus (HBV). Telbivudine is not a cure for HBV, but the drug may lower viral load and prevent infection of new hepatocytes. When compared to lamivudine 100 mg/day for 1 year in patients with HBeAg-positive chronic HBV, patients receiving telbivudine …
What is Telavancin Telavancin (Vibativ) is the first FDA-approved agent in the lipoglycopeptide class of antibiotics. It is a semi-synthetic derivative of vancomycin with rapid concentration-dependent bactericidal action against selected gram-positive organisms, including methicillin-resistant Staphylococcus aureus (MRSA). It is administered once daily, a potential advantage over some other antimicrobial agents with a similar spectrum of activity; however, …
What is Telaprevir Telaprevir is an NS3/4A protease inhibitor, indicated for the treatment of genotype 1 chronic hepatitis C infection in adults with compensated liver disease who are treatment-naive or who have previously had an inadequate responded to interferon-based drug therapy. Telaprevir must be used in combination with peginterferon alfa and ribavirin; therefore, precautions applying …
What is Tegaserod Tegaserod is a selective serotonin (5HT-4) partial agonist belonging to a chemical class known as the aminoguanidine indoles. Tegaserod is indicated for the treatment of adult women less than 65 years of age with irritable bowel syndrome with constipation (IBS-C). Tegaserod has been shown to be effective in treating abdominal pain, altered …
What is Teduglutide Teduglutide is a recombinant glucagon-like peptide-2 (GLP-2) analog. The drug is used to treat pediatric and adult patients with intestinal failure secondary to short bowel syndrome (SBS) who are dependent on parenteral nutrition. Brand Name Gattex Indications short bowel syndrome For the treatment of short bowel syndrome in patients who are dependent …
What is Tedizolid Tedizolid is an oxazolidinone antibiotic approved for the treatment of acute bacterial skin and skin structure infections (ABSSSI) caused by certain susceptible bacteria like Staphylococcus aureus (including methicillin-susceptible and methicillin-resistant strains), various Streptococcus species, and Enterococcus faecalis. Two clinical trials demonstrated that tedizolid was as effective as linezolid for the treatment of ABSSSI. The safety and effectiveness …