How is CRMO diagnosed?
- • X-rays: mixed osteolytic and sclerotic lesions, although may be normal initially.
- • Whole body magnetic resonance imaging (MRI) with STIR imaging is preferred; otherwise, focal MRI or technetium bone scan.
- • Many, but not all, patients have elevations in ESR and CRP. WBC can be normal or elevated.
- • Bone biopsy to confirm inflammatory changes and exclude infection, malignancy.