How is CRMO diagnosed

How is CRMO diagnosed?

  • • X-rays: mixed osteolytic and sclerotic lesions, although may be normal initially.
  • • Whole body magnetic resonance imaging (MRI) with STIR imaging is preferred; otherwise, focal MRI or technetium bone scan.
  • • Many, but not all, patients have elevations in ESR and CRP. WBC can be normal or elevated.
  • • Bone biopsy to confirm inflammatory changes and exclude infection, malignancy.

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