How is HIDS diagnosed
What laboratory abnormalities may be present in HIDS?
• Inflammatory markers (ESR, CRP, and WBC) and urinary mevalonic acid will commonly be increased during flares.
• IgD levels are elevated in 80% of patients; as such, elevation of IgD is not necessary for the diagnosis of HIDS and may represent an epiphenomenon.
• In patients with elevated IgD levels, the levels remain elevated between disease flares.
• IgA levels are elevated in 80% of patients.