How is HIDS diagnosed

How is HIDS diagnosed

What laboratory abnormalities may be present in HIDS?

• Inflammatory markers (ESR, CRP, and WBC) and urinary mevalonic acid will commonly be increased during flares.

• IgD levels are elevated in 80% of patients; as such, elevation of IgD is not necessary for the diagnosis of HIDS and may represent an epiphenomenon.

• In patients with elevated IgD levels, the levels remain elevated between disease flares.

• IgA levels are elevated in 80% of patients.

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