What is Sulfacetamide and Sulfur combination medicine
Sulfacetamide and sulfur are used together in a topical preparation to treat acne rosacea, acne vulgaris, and seborrheic dermatitis. Sulfacetamide is a sulfonamide antibiotic.
Sulfur is a topical antimicrobial and keratolytic agent that causes a peeling and drying action.
Sulfacetamide and sulfur has been historically used in dermatology for many decades, and was initially marketed for use before 1962, which is when Congress passed the amended Federal Food, Drug, and Cosmetic Act requiring that the FDA establish both safety and efficacy for all subsequently approved drugs. Sulfacetamide; sulfur is an unapproved marketed drug that has not been formally evaluated by the FDA.
Indications & Dosage
- acne rosacea
- acne vulgaris
- seborrheic dermatitis
Side Effects
- agranulocytosis
- contact dermatitis
- edema
- erythema
- exfoliative dermatitis
- fever
- hemolytic anemia
- jaundice
- photosensitivity
- pruritus
- purpura
- skin irritation
- Stevens-Johnson syndrome
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- accidental exposure
- asthma
- breast-feeding
- carbonic anhydrase inhibitor hypersensitivity
- children
- infants
- neonates
- ocular exposure
- pregnancy
- renal disease
- renal failure
- renal impairment
- skin abrasion
- skin photosensitivity disorder
- sulfite hypersensitivity
- sulfonamide hypersensitivity
- sulfonylurea hypersensitivity
- sunlight (UV) exposure
- thiazide diuretic hypersensitivity
Interactions
- Acetohexamide
- Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
- Aliskiren; Hydrochlorothiazide, HCTZ
- Amiloride; Hydrochlorothiazide, HCTZ
- Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
- Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
- Atenolol; Chlorthalidone
- Azilsartan; Chlorthalidone
- Benazepril; Hydrochlorothiazide, HCTZ
- Bendroflumethiazide; Nadolol
- Bisoprolol; Hydrochlorothiazide, HCTZ
- Candesartan; Hydrochlorothiazide, HCTZ
- Captopril; Hydrochlorothiazide, HCTZ
- Chlorothiazide
- Chlorpropamide
- Chlorthalidone
- Chlorthalidone; Clonidine
- Enalapril; Hydrochlorothiazide, HCTZ
- Eprosartan; Hydrochlorothiazide, HCTZ
- Fosinopril; Hydrochlorothiazide, HCTZ
- Gentamicin
- Glimepiride
- Glimepiride; Pioglitazone
- Glimepiride; Rosiglitazone
- Glipizide
- Glipizide; Metformin
- Glyburide
- Glyburide; Metformin
- Hydralazine; Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ
- Hydrochlorothiazide, HCTZ; Irbesartan
- Hydrochlorothiazide, HCTZ; Lisinopril
- Hydrochlorothiazide, HCTZ; Losartan
- Hydrochlorothiazide, HCTZ; Methyldopa
- Hydrochlorothiazide, HCTZ; Metoprolol
- Hydrochlorothiazide, HCTZ; Moexipril
- Hydrochlorothiazide, HCTZ; Olmesartan
- Hydrochlorothiazide, HCTZ; Propranolol
- Hydrochlorothiazide, HCTZ; Quinapril
- Hydrochlorothiazide, HCTZ; Spironolactone
- Hydrochlorothiazide, HCTZ; Telmisartan
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydrochlorothiazide, HCTZ; Valsartan
- Methoxsalen
- Methyclothiazide
- Metolazone
- Photosensitizing agents (topical)
- Silver Nitrate
- Silver Sulfadiazine
- Sulfonylureas
- Thiazide diuretics
- Tolazamide
- Tolbutamide
- Voriconazole
