What is Sacrosidase

Sacrosidase is an oral enzyme produced as a by-product of the manufacture of baker’s yeast (Saccharomyces cerevisiae). It is used for treating sucrase deficiency associated with congenital sucrase-isomaltase deficiency (CSID).

CSID is a rare genetic disease in which the body lacks sucrase and isomaltase, enzymes necessary to break down and absorb sucrose and isomaltose, respectively. 

Brand Name



  • congenital sucrase-isomaltase deficiency (CSID)

Side Effects

  • abdominal pain
  • constipation
  • dehydration
  • diarrhea
  • headache
  • insomnia
  • nausea
  • vomiting
  • wheezing

Monitoring Parameters

  • laboratory monitoring not necessary


  • asthma
  • breast-feeding
  • diabetes mellitus
  • glycerin hypersensitivity
  • infants
  • neonates
  • papain hypersensitivity
  • pregnancy
  • yeast hypersensitivity


  • food

Food: (Moderate) Sacrosidase should not be reconstituted or consumed with acidic food, like fruit juice, since the acidity may reduce the enzyme activity.