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What is Revefenacin
Revefenacin is a respiratory antimuscarinic that acts as a bronchodilator.
It is used for the long-term maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Brand Name
YUPELRI
Indications
- chronic bronchitis
- chronic obstructive pulmonary disease (COPD)
- emphysema
For the maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema
Side Effects
- anaphylactoid reactions
- angioedema
- back pain
- blurred vision
- bronchospasm
- cough
- cycloplegia
- dizziness
- dysuria
- headache
- hypertension
- infection
- mydriasis
- ocular hypertension
- pharyngitis
- pruritus
- urinary retention
- urticaria
Monitoring Parameters
- pulmonary function tests (PFTs)
Contraindications
- acute bronchospasm
- anticholinergic medications
- breast-feeding
- cardiac disease
- children
- closed-angle glaucoma
- driving or operating machinery
- geriatric
- hepatic disease
- infants
- ocular exposure
- paradoxical bronchospasm
- pregnancy
- prostatic hypertrophy
- urinary retention
- urinary tract obstruction
Interactions
- Amoxicillin; Clarithromycin; Lansoprazole
- Amoxicillin; Clarithromycin; Omeprazole
- Anticholinergics
- Atazanavir
- Atazanavir; Cobicistat
- Atropine
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Edrophonium
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benztropine
- Chlordiazepoxide; Clidinium
- Clarithromycin
- Cobicistat
- Cyclosporine
- Daclatasvir
- Darunavir; Cobicistat
- Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
- Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
- Dicyclomine
- Elexacaftor; tezacaftor; ivacaftor
- Eltrombopag
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
- Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
- Erythromycin
- Erythromycin; Sulfisoxazole
- Flavoxate
- Gemfibrozil
- Glecaprevir; Pibrentasvir
- Glycopyrrolate
- Glycopyrrolate; Formoterol
- Homatropine; Hydrocodone
- Hyoscyamine
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Indacaterol; Glycopyrrolate
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Isoniazid, INH; Rifampin
- Leflunomide
- Letermovir
- Lopinavir; Ritonavir
- Mepenzolate
- Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
- Methscopolamine
- Obeticholic Acid
- Ombitasvir; Paritaprevir; Ritonavir
- Oxybutynin
- Propantheline
- Rifampin
- Scopolamine
- Simeprevir
- Sofosbuvir; Velpatasvir
- Sofosbuvir; Velpatasvir; Voxilaprevir
- Telithromycin
- Teriflunomide
- Trihexyphenidyl
