What's on this Page
What is Reteplase r PA
Reteplase is an intravenous recombinant plasminogen activator indicated for the treatment of acute ST-elevation myocardial infarction (STEMI) to reduce the risk of death and heart failure.
Brand Name
- Retavase
- Retavase Half-Kit
Indications & Dosage
- acute myocardial infarction, STEMI
- arterial thromboembolism
- occluded arteriovenous (AV) cannula
- occluded IV catheter
For the treatment of acute myocardial infarction, STEMI to reduce the risk of death and heart failure
Side Effects
- anaphylactoid reactions
- anemia
- bleeding
- cholesterol microembolization
- dyspnea
- edema
- erythema
- GI bleeding
- hypertension
- hypotension
- intracranial bleeding
- livedo reticularis
- myocardial infarction
- pancreatitis
- pruritus
- purple-toe syndrome
- rash
- renal failure (unspecified)
- rhabdomyolysis
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- aneurysm
- arteriovenous malformation
- bleeding
- brain tumor
- breast-feeding
- coagulopathy
- head trauma
- hypertension
- intracranial mass
- intramuscular injections
- labor
- laboratory test interference
- obstetric delivery
- pregnancy
- stroke
- surgery
- venipuncture
Interactions
- Abciximab
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Alpha interferons
- Altretamine
- Aminocaproic Acid
- Aminosalicylate sodium, Aminosalicylic acid
- Anagrelide
- Antimetabolites
- Antithrombin III
- Antithymocyte Globulin
- Apixaban
- Aprotinin
- Argatroban
- Arsenic Trioxide
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Betrixaban
- Bexarotene
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bivalirudin
- Chlorambucil
- Choline Salicylate; Magnesium Salicylate
- Cilostazol
- Clofarabine
- Clopidogrel
- Dabigatran
- Dalteparin
- Danaparoid
- Danazol
- Defibrotide
- Denileukin Diftitox
- Desirudin
- Desvenlafaxine
- Dipyridamole
- Drotrecogin Alfa
- Duloxetine
- Edoxaban
- Enoxaparin
- Eptifibatide
- Estramustine
- Fish Oil, Omega-3 Fatty Acids (Dietary Supplements)
- Folate analogs
- Fondaparinux
- Garlic, Allium sativum
- Ginger, Zingiber officinale
- Ginkgo, Ginkgo biloba
- Green Tea
- Heparin
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Ibritumomab Tiuxetan
- Icosapent ethyl
- Intravenous Lipid Emulsions
- Lepirudin
- Levomilnacipran
- Lomustine, CCNU
- Magnesium Salicylate
- Methoxsalen
- Methylsulfonylmethane, MSM
- Milnacipran
- Nonsteroidal antiinflammatory drugs
- Pegaspargase
- Pentosan
- Photosensitizing agents (topical)
- Platelet Inhibitors
- Prasugrel
- Rivaroxaban
- Salicylates
- Salsalate
- Selective serotonin reuptake inhibitors
- Sodium Hyaluronate, Hyaluronic Acid
- Sulfinpyrazone
- Thrombin Inhibitors
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tirofiban
- Tranexamic Acid
- Trazodone
- Tretinoin, ATRA
- Venlafaxine
- Verteporfin
- Vilazodone
- Vorapaxar
- Vorinostat
- Vortioxetine
- Warfarin
