Salicylic Acid

What is Salicylic Acid

Salicylic acid is a topical keratolytic agent. It is used to remove excess keratin in hyperkeratotic skin disorders such as common and plantar warts, psoriasis, seborrheic dermatitis, calluses, and corns. Salicylic acid also is used to treat acne.

Salicylic acid works by causing desquamation of the horny layer of skin. Prolonged or repeated daily use over large areas of skin may result in salicylism, especially in children and patients with renal or hepatic impairment. This drug was approved by the FDA in 1939.

Indications

  • acne vulgaris
  • ichthyosis
  • pityriasis rubra pilaris
  • Propionibacterium acnes
  • psoriasis
  • seborrheic dermatitis
  • verruca plantaris
  • verruca vulgaris

Side Effects

  • anaphylactoid reactions
  • erythema
  • pruritus
  • skin irritation

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • accidental exposure
  • breast-feeding
  • children
  • diabetes mellitus
  • hepatic disease
  • influenza
  • ocular exposure
  • peripheral vascular disease
  • pregnancy
  • renal impairment
  • salicylate hypersensitivity
  • varicella

Interactions

  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Adapalene
  • Adapalene; Benzoyl Peroxide
  • Aminosalicylate sodium, Aminosalicylic acid
  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzoyl Peroxide
  • Benzoyl Peroxide; Clindamycin
  • Benzoyl Peroxide; Erythromycin
  • Benzoyl Peroxide; Sulfur
  • Bismuth Subsalicylate
  • Bismuth Subsalicylate; Metronidazole; Tetracycline
  • Choline Salicylate; Magnesium Salicylate
  • Clindamycin
  • Clindamycin; Tretinoin
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Magnesium Salicylate
  • Mequinol; Tretinoin
  • Retinoids
  • Salicylates
  • Salsalate
  • Trifarotene

Brand Names

Akurza | Aliclen | Bensal HP | Clear Away | Clear Away Liquid | Clear Away One Step | Clear Away Plantar | Clearasil 3-in-1 | Clearasil Blackhead Clearing Scrub | Clearasil Foaming Cleanser | Clearasil Oil Control | Clearasil Overnight Acne Defense | Clearasil Rapid Rescue Deep Treatment | Clearasil Total Control | Clearasil Ultra Astringent | Clearasil Ultra Scrub | Compound W | Corn/Callus Remover | Curad Mediplast | Dermarest Psoriasis Moisturizer | Dermarest Psoriasis Overnight Treatment | Dermarest Psoriasis Scalp Treatment | Dermarest Psoriasis Shampoo plus Conditioner | Dermarest Psoriasis Skin Treatment | Dr. Scholl’s Callus Removers | Dr. Scholl’s Extra Thick Callus Remover | Dr. Scholl’s One Step Callus Remover | DuoFilm Wart Remover | Freezone | Gordofilm | Hydrisalic | Ionil | Ionil Plus | Keralyt | Keralyt Scalp Complete | MOSCO Callus & Corn Remover | MOSCO One Step Corn Remover | Neutrogena Acne Wash | Occlusal-HP | P&S | RE SA | SalAC | Salactic Film | Salacyn | Salex | Salimez | Salimez Forte | Salisol | Salisol Forte | Salitech | Salitech Forte | Salitop | Salkera | Salvax | Scalpicin 2 in 1 Anti-Dandruff | Selsun Blue | Thera-Sal | Trans-Ver-Sal | UltraSal-ER | VIRASAL | Wart-Off | XALIX