Glycopyrronium Brand Name– Qbrexza
What is Glycopyrronium
Glycopyrronium is an anticholinergic agent indicated for topical treatment of primary axillary hyperhidrosis in adults and pediatric patients 9 years of age and older.
The product is available as a pre-moistened cloth that should be apply no more frequently than once every 24 hours. Patients who apply the drug in the presence of high ambient temperature may be at increased risk for heat illness (e.g., hyperpyrexia, heat stroke).
Instruct drug recipients to watch for a generalized lack of sweating when in hot or very warm environments, and to avoid use if not sweating in these conditions. Use of the drug should also be avoided in patients with medical conditions that may be exacerbated by the anticholinergic actions of glycopyrronium.
Indications
- hyperhidrosis
For the treatment of primary axillary hyperhidrosis
Side Effects
- blurred vision
- constipation
- contact dermatitis
- erythema
- headache
- mydriasis
- nasal dryness
- pharyngitis
- pruritus
- rash
- skin irritation
- urinary retention
- xerophthalmia
- xerostomia
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- ambient temperature increase
- anticholinergic medications
- breast-feeding
- cardiac arrhythmias
- contact lenses
- coronary artery disease
- driving or operating machinery
- glaucoma
- heart failure
- hemorrhagic shock
- hypertension
- ileus
- myasthenia gravis
- pregnancy
- prostatic hypertrophy
- Sjogren’s syndrome
- tachycardia
- toxic megacolon
- ulcerative colitis
- urinary retention
- urinary tract obstruction
Interactions
- Albuterol; Ipratropium
- Anticholinergics
- Atropine
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Atropine; Difenoxin
- Atropine; Diphenoxylate
- Atropine; Edrophonium
- Atropine; Hyoscyamine; Phenobarbital; Scopolamine
- Belladonna Alkaloids; Ergotamine; Phenobarbital
- Belladonna; Opium
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benztropine
- Chlordiazepoxide; Clidinium
- Dicyclomine
- Flavoxate
- Glycopyrrolate
- Glycopyrrolate; Formoterol
- Homatropine; Hydrocodone
- Hyoscyamine
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Indacaterol; Glycopyrrolate
- Ipratropium
- Mepenzolate
- Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
- Methscopolamine
- Oxybutynin
- Propantheline
- Scopolamine
- Solifenacin
- Tolterodine
- Trihexyphenidyl
- Trospium