Ginger Zingiber officinale

Ginger Zingiber officinale Brand Names- Dramamine Motion Sickness Relief | Dramamine-N

What is Ginger Zingiber officinale

Ginger is a dietary supplement derived from the underground stem (rhizome) of the perennial plant Zingiber officinale Roscoe.

Usually grown in warmer climates, ginger is often referred to by its country of origin. Jamaican ginger, African ginger, and Cochin ginger (China) contain different concentrations of the active ingredient(s).

Ginger is chemically classified as an essential oil with pungent principles. The dried rhizome contains approximately 1—3% volatile oil which is the source of ginger’s characteristic aroma; an oleoresin contains the pungent properties. Ginger has been in use as a digestive aid, spice, and flavoring agent for over 20 centuries. In China, the roots and rhizomes are also used as pesticides against fungal spores and aphids.

Primarily used as an antiemetic, ginger is considered the herbal remedy of choice for the prevention of motion sickness.

The German Commission E lists anorexia as an indication for a fixed combination of Ginger root, Gentian root and Wormwood. Currently, there is no standardized measure to compare the potency or ingredient content of products that contain ginger.

Preparations can vary widely in chemical content related to the country of origin or manufacturer and may contain inactive adulterants. Reports of neurotoxicity associated with Jamaican ginger in the 1930’s were due to an adulterant used in the extract.

Ginger is listed in the USP and is Generally Recognized As Safe (GRAS) by the FDA.

Indications

  1. chemotherapy-induced nausea/vomiting prophylaxis
  2. dyspepsia
  3. hyperemesis gravidarum
  4. motion sickness
  5. post-operative nausea/vomiting (PONV) prophylaxis
  6. pregnancy-induced nausea/vomiting
  7. rheumatoid arthritis

Side Effects

  1. bleeding
  2. contact dermatitis
  3. diarrhea
  4. dyspepsia
  5. headache
  6. pyrosis (heartburn)
  7. rash

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • anticoagulant therapy
  • bleeding
  • breast-feeding
  • cardiac arrhythmias
  • cardiac disease
  • children
  • cholelithiasis
  • diabetes mellitus
  • gallbladder disease
  • geriatric
  • hypoglycemia
  • infants
  • neonates
  • pregnancy
  • thrombolytic therapy

Interactions

  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
  • Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
  • Acetaminophen; Dextromethorphan; Phenylephrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Guaifenesin; Phenylephrine
  • Acetaminophen; Pseudoephedrine
  • Acrivastine; Pseudoephedrine
  • Adenosine
  • Aminoglycosides
  • Amlodipine; Celecoxib
  • Anticoagulants
  • Articaine; Epinephrine
  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
  • Beta-adrenergic blockers
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Dextromethorphan; Phenylephrine
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Bupivacaine; Lidocaine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Phenylephrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Celecoxib
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlophedianol; Guaifenesin; Phenylephrine
  • Chlorpheniramine; Dextromethorphan; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Phenylephrine
  • Chlorpheniramine; Pseudoephedrine
  • Class IA Antiarrhythmics
  • Class IC Antiarrhythmics
  • Co-Enzyme Q10, Ubiquinone
  • Codeine; Phenylephrine; Promethazine
  • Desloratadine; Pseudoephedrine
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dextromethorphan; Diphenhydramine; Phenylephrine
  • Dextromethorphan; Guaifenesin; Phenylephrine
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Diclofenac
  • Diclofenac; Misoprostol
  • Diflunisal
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diltiazem
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Diphenhydramine; Phenylephrine
  • Dobutamine
  • Dopamine
  • Epinephrine
  • Esomeprazole; Naproxen
  • Ethanol
  • Etodolac
  • Famotidine; Ibuprofen
  • Fenoprofen
  • Fexofenadine; Pseudoephedrine
  • Flurbiprofen
  • Garlic, Allium sativum
  • Ginkgo, Ginkgo biloba
  • Ginseng, Panax ginseng
  • Green Tea
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Phenylephrine
  • Guaifenesin; Pseudoephedrine
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Ibuprofen
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Inamrinone
  • Indomethacin
  • Isoproterenol
  • Ketoprofen
  • Ketorolac
  • Lansoprazole; Naproxen
  • Lidocaine
  • Lidocaine; Prilocaine
  • Loratadine; Pseudoephedrine
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Meloxicam
  • Methylsulfonylmethane, MSM
  • Mexiletine
  • Midodrine
  • Milrinone
  • Nabumetone
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Nesiritide, BNP
  • Nonsteroidal antiinflammatory drugs
  • Norepinephrine
  • Oxaprozin
  • Pentoxifylline
  • Phenylephrine
  • Phenylephrine; Promethazine
  • Piroxicam
  • Platelet Inhibitors
  • Prilocaine; Epinephrine
  • Pseudoephedrine
  • Rofecoxib
  • Sulindac
  • Thrombolytic Agents
  • Tolmetin
  • Trandolapril; Verapamil
  • Valdecoxib
  • Verapamil
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