Do some NSAIDs inhibit COX 1 or COX 2 preferentially

Do some NSAIDs inhibit COX 1 or COX 2 preferentially?

Yes. A classification system is listed below according to the NSAID ability to inhibit COX-1 and/or COX-2 in therapeutic doses.

NomenclatureNSAIDs in this Classification
COX-1 selectiveLow-dose ASA (irreversibly binds to serine 530 on COX-1)
COX nonselectiveIbuprofen, naproxen, meclomen, indomethacin
COX-2 selectiveEtodolac, diclofenac, nabumetone, meloxicam
COX-2 highly selectiveCelecoxib

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