Beneficial effects of NSAIDs

What are the beneficial effects of NSAIDs?

  • Analgesia —some studies have shown equivalent reductions in acute pain compared with narcotics.
  • Antipyresis —NSAIDs inhibit PGs in the central nervous system (CNS), which reduces fever.
  • Antiinflammatory —probably achieved by a number of mechanisms (PG inhibition is the most understood and thought to represent the main mechanism of action).
  • Antiplatelet —most NSAIDs decrease platelet aggregation by preventing thromboxane A2 (TXA ) production, which is important in platelet activation and clotting.
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