Citric Acid Potassium Citrate Sodium Citrate

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Citric Acid Potassium Citrate Sodium Citrate Brand Names

Cytra-3 | Polycitra | Polycitra-LC | Tricitrates | VIRTRATE

What is Citric Acid Potassium Citrate Sodium Citrate

Citric acid potassium citrate sodium citrate solution is an alkalinizing agent.

At recommended doses, it alkalinizes the urine without producing a systemic alkalosis and will not neutralize the gastric juice or disturb digestion.

Uses include conditions where long-term maintenance of an alkaline urine is desirable, such as in patients with uric acid and cystine calculi of the urinary tract. It can be used as an adjuvant with uricosuric agents in gout therapy, since urates tend to crystallize out of an acid urine.

It is also effective in correcting the acidosis of certain renal tubular disorders.

This product is highly concentrated, and when administered after meals and before bedtime, allows one to maintain an alkaline urine pH around the clock, usually without the necessity of a 2 AM dose.

Indications

  1. metabolic acidosis
  2. nephrolithiasis
  3. nephrolithiasis prevention
  4. renal calculus
  5. renal tubular acidosis (RTA)
  6. urinary alkalinization

For urinary alkalinization for nephrolithiasis prevention (due to nephrolithiasis or renal calculus with uric acid or cystine salts or during use of uricosuric agents); or for the treatment of chronic metabolic acidosis associated with renal tubular acidosis (RTA) or other renal tubular disorders

Side Effects

  1. abdominal pain
  2. confusion
  3. diarrhea
  4. hyperkalemia
  5. nausea
  6. vomiting
  7. weakness

Monitoring Parameters

  • serum electrolytes

Contraindications

  • adrenal insufficiency
  • ascites
  • atrial fibrillation
  • atrial flutter
  • breast-feeding
  • burns
  • cardiac arrhythmias
  • dehydration
  • diabetic ketoacidosis
  • diarrhea
  • digitalis toxicity
  • eclampsia
  • heart failure
  • hepatic disease
  • hyperkalemia
  • hypertension
  • hypocalcemia
  • metabolic acidosis
  • oliguria
  • peripheral edema
  • preeclampsia
  • pregnancy
  • pulmonary edema
  • renal disease
  • renal failure
  • renal impairment
  • ventricular arrhythmias
  • ventricular fibrillation
  • ventricular tachycardia

Interactions

  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Pseudoephedrine
  • Acrivastine; Pseudoephedrine
  • Aliskiren
  • Aliskiren; Amlodipine
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Aliskiren; Valsartan
  • Aluminum Hydroxide
  • Aluminum Hydroxide; Magnesium Carbonate
  • Aluminum Hydroxide; Magnesium Hydroxide
  • Aluminum Hydroxide; Magnesium Hydroxide; Simethicone
  • Aluminum Hydroxide; Magnesium Trisilicate
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminosalicylate sodium, Aminosalicylic acid
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Ammonium Chloride
  • Amphetamines
  • Angiotensin II receptor antagonists
  • Angiotensin-converting enzyme inhibitors
  • Antacids
  • Anticholinergics
  • Aspirin, ASA
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Citric Acid; Sodium Bicarbonate
  • Aspirin, ASA; Dipyridamole
  • Aspirin, ASA; Omeprazole
  • Aspirin, ASA; Oxycodone
  • Aspirin, ASA; Pravastatin
  • Atropine
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Edrophonium
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • Azelastine; Fluticasone
  • Azilsartan
  • Azilsartan; Chlorthalidone
  • Beclomethasone
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzphetamine
  • Benztropine
  • Betamethasone
  • Bismuth Subsalicylate
  • Bismuth Subsalicylate; Metronidazole; Tetracycline
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide
  • Budesonide; Formoterol
  • Calcium Carbonate
  • Calcium Carbonate; Magnesium Hydroxide
  • Calcium Carbonate; Risedronate
  • Calcium Carbonate; Simethicone
  • Candesartan
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Captopril
  • Captopril; Hydrochlorothiazide, HCTZ
  • Carbetapentane; Pseudoephedrine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Pseudoephedrine
  • Celecoxib
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlordiazepoxide; Clidinium
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorpropamide
  • Choline Salicylate; Magnesium Salicylate
  • Ciclesonide
  • Colchicine
  • Colchicine; Probenecid
  • Corticosteroids
  • Cortisone
  • Cyclosporine
  • Deflazacort
  • Desloratadine; Pseudoephedrine
  • Dexamethasone
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Dextromethorphan; Quinidine
  • Diclofenac
  • Diclofenac; Misoprostol
  • Dicyclomine
  • Diflunisal
  • Digoxin
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Donepezil; Memantine
  • Drospirenone
  • Drospirenone; Estradiol
  • Drospirenone; Ethinyl Estradiol
  • Drospirenone; Ethinyl Estradiol; Levomefolate
  • Enalapril, Enalaprilat
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Ephedrine
  • Eplerenone
  • Eprosartan
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Esomeprazole; Naproxen
  • Etodolac
  • Famotidine; Ibuprofen
  • Fenoprofen
  • Fexofenadine; Pseudoephedrine
  • Flavoxate
  • Flecainide
  • Fludrocortisone
  • Flunisolide
  • Flurbiprofen
  • Fluticasone
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • food
  • Formoterol; Mometasone
  • Fosinopril
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Glycopyrrolate
  • Glycopyrrolate; Formoterol
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Pseudoephedrine
  • Heparin
  • Homatropine; Hydrocodone
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydrocortisone
  • Hyoscyamine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibuprofen
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Indacaterol; Glycopyrrolate
  • Indomethacin
  • Irbesartan
  • Ketoprofen
  • Ketorolac
  • Lansoprazole; Naproxen
  • Lisdexamfetamine
  • Lisinopril
  • Lithium
  • Loperamide
  • Loperamide; Simethicone
  • Loratadine; Pseudoephedrine
  • Losartan
  • Magnesium Hydroxide
  • Magnesium Salicylate
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Meloxicam
  • Memantine
  • Mepenzolate
  • Methamphetamine
  • Methenamine
  • Methenamine; Sodium Acid Phosphate
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methscopolamine
  • Methylprednisolone
  • Moexipril
  • Mometasone
  • Nabumetone
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Nebivolol; Valsartan
  • Nonsteroidal antiinflammatory drugs
  • Olmesartan
  • Oxaprozin
  • Oxybutynin
  • Penicillin G
  • Perindopril
  • Perindopril; Amlodipine
  • Piroxicam
  • Prednisolone
  • Prednisone
  • Propantheline
  • Pseudoephedrine
  • Quinapril
  • Quinidine
  • Quinine
  • Ramipril
  • Rofecoxib
  • Sacubitril; Valsartan
  • Salicylates
  • Salsalate
  • Scopolamine
  • Sodium Polystyrene Sulfonate
  • Spironolactone
  • Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
  • Sulindac
  • Tacrolimus
  • Telmisartan
  • Tolmetin
  • Trandolapril
  • Trandolapril; Verapamil
  • Triamcinolone
  • Triamterene
  • Trihexyphenidyl
  • Trimethoprim
  • Valdecoxib
  • Valsartan

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