Chlophedianol Dexbrompheniramine

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Chlophedianol Dexbrompheniramine Brand Name– Chlo Hist

What is Chlophedianol Dexbrompheniramine

Chlophedianol dexbrompheniramine is a combination of a cough suppressant and sedating antihistamine used to help relieve cough and symptoms of the common cold or allergic rhinitis.

Chlophedianol is a centrally-acting non-opioid antitussive used to relieve dry, irritating coughs. In some countries, chlophedianol is known as clophedanol.

Dexbrompheniramine is a sedating antihistamine (H1-blocker) of the alkylamine class that dries the nasal and sinus passages secondary to its anticholinergic activity, and treats histamine-mediated symptoms such as rhinorrhea and sneezing.

Products are labeled for use in adult and pediatric patients 6 years and older.

Indications

  1. allergic rhinitis
  2. common cold
  3. cough
  4. rhinorrhea

For the temporary relief of cough, rhinorrhea, and other symptoms of the common cold or allergic rhinitis

Side Effects

  1. abdominal pain
  2. angina
  3. anorexia
  4. anxiety
  5. arrhythmia exacerbation
  6. AV block
  7. blurred vision
  8. confusion
  9. constipation
  10. delirium
  11. diplopia
  12. dizziness
  13. drowsiness
  14. dyskinesia
  15. dyspepsia
  16. dysuria
  17. euphoria
  18. excitability
  19. hyperhidrosis
  20. hypotension
  21. impotence (erectile dysfunction)
  22. irritability
  23. lethargy
  24. menstrual irregularity
  25. mydriasis
  26. nasal congestion
  27. nausea
  28. palpitations
  29. paresthesias
  30. polyuria
  31. psychosis
  32. pyrosis (heartburn)
  33. rash
  34. restlessness
  35. seizures
  36. sinus tachycardia
  37. tinnitus
  38. tremor
  39. urinary retention
  40. vertigo
  41. visual impairment
  42. vomiting
  43. weakness
  44. wheezing
  45. xerophthalmia
  46. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • anticholinergic medications
  • asthma
  • bladder obstruction
  • breast-feeding
  • bronchitis
  • children
  • chronic obstructive pulmonary disease (COPD)
  • closed-angle glaucoma
  • coadministration with other CNS depressants
  • contact lenses
  • driving or operating machinery
  • emphysema
  • ethanol ingestion
  • geriatric
  • GI obstruction
  • hepatic disease
  • ileus
  • increased intraocular pressure
  • infants
  • MAOI therapy
  • neonates
  • pregnancy
  • prostatic hypertrophy
  • seizure disorder
  • status asthmaticus
  • urinary retention

Interactions

  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Codeine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Propoxyphene
  • Alfentanil
  • Alosetron
  • Amantadine
  • Ambenonium Chloride
  • Amoxapine
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamine; Dextroamphetamine Salts
  • Anticholinergics
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Oxycodone
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Azelastine
  • Azelastine; Fluticasone
  • Baclofen
  • Belladonna; Opium
  • Benzodiazepines
  • Benzphetamine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Buspirone
  • Butorphanol
  • Cannabidiol
  • Capsaicin; Metaxalone
  • Carbetapentane; Chlorpheniramine
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carisoprodol
  • Cenobamate
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpromazine
  • Chlorzoxazone
  • Clobazam
  • Clozapine
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • COMT inhibitors
  • Dantrolene
  • Daratumumab; Hyaluronidase
  • Desloratadine
  • Desloratadine; Pseudoephedrine
  • Dexmedetomidine
  • Dextroamphetamine
  • Dextromethorphan; Promethazine
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Dronabinol
  • Entacapone
  • Eszopiclone
  • Ethanol
  • Etomidate
  • Fentanyl
  • Flibanserin
  • Fluphenazine
  • Fospropofol
  • Gabapentin
  • Galantamine
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Heparin
  • Homatropine; Hydrocodone
  • Hyaluronidase
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydantoins
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Ibuprofen; Oxycodone
  • Isocarboxazid
  • Ketamine
  • Lasmiditan
  • Lemborexant
  • Levocetirizine
  • Levomethadyl
  • Levorphanol
  • Loratadine
  • Loratadine; Pseudoephedrine
  • Loxapine
  • Lumateperone
  • Lurasidone
  • Magnesium Salts
  • Melatonin
  • Meperidine
  • Meperidine; Promethazine
  • Meprobamate
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methocarbamol
  • Metoclopramide
  • Metyrosine
  • Minocycline
  • Mirtazapine
  • Mitotane
  • Molindone
  • Monoamine oxidase inhibitors
  • Morphine
  • Morphine; Naltrexone
  • Nabilone
  • Nalbuphine
  • Nefazodone
  • Opiate Agonists
  • Orphenadrine
  • Oxycodone
  • Oxymorphone
  • Paroxetine
  • Pentazocine
  • Pentazocine; Naloxone
  • Perampanel
  • Perphenazine
  • Perphenazine; Amitriptyline
  • Phenelzine
  • Phenylephrine; Promethazine
  • Pitolisant
  • Pramipexole
  • Pregabalin
  • Procarbazine
  • Prochlorperazine
  • Promethazine
  • Propofol
  • Propoxyphene
  • Ramelteon
  • Rasagiline
  • Remifentanil
  • Rituximab; Hyaluronidase
  • Rivastigmine
  • Ropinirole
  • Safinamide
  • Selegiline
  • Sincalide
  • Sodium Iodide
  • Sufentanil
  • Suvorexant
  • Tacrine
  • Tasimelteon
  • Thalidomide
  • Thioridazine
  • Thiothixene
  • Tolcapone
  • Tranylcypromine
  • Trastuzumab; Hyaluronidase
  • Trifluoperazine
  • Trimethobenzamide
  • Trospium
  • Vigabatrin
  • Vilazodone
  • Zaleplon
  • Ziconotide
  • Zolpidem

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