Carbetapentane Guaifenesin Phenylephrine

Carbetapentane Guaifenesin Phenylephrine Brand Names

Aquatab C | Carbatab-12 | Carbatuss | Carbetaplex | Extendryl GCP | Gentex 30 | Gentex LQ | Levall | Oratuss 12 | Phencarb GG | Zinx Cough

What is Carbetapentane Guaifenesin Phenylephrine

Carbetapentane guaifenesin phenylephrine is a combination product which contains an antitussive, expectorant, and decongestant.

The combination is used for temporary relief of nonproductive cough accompanying respiratory tract congestion associated with the common cold, influenza, sinusitis, and bronchitis.

Carbetapentane is a non-opioid, centrally acting cough suppressant.

The antitussive effect of carbetapentane is less potent than that of opiates. However, unlike opiates, carbetapentane has not been associated with substance abuse.

Guaifenesin, an oral expectorant, is commonly used to treat cough due to colds and minor upper respiratory infections. Despite its long history of use since the 1950’s, the efficacy of guaifenesin has only recently been substantiated.

Although guaifenesin may be used as an expectorant in both productive and non-productive coughs, it is especially useful in the treatment of dry, non-productive coughs which tend to injure the respiratory mucous membranes.

Phenylephrine is a sympathomimetic amine used as a decongestant to decrease nasal and sinus congestion.

Pharmacologically, it most closely resembles the older drug methoxamine.

Carbetapentane guaifenesin phenylephrine is available in various formulations by prescription.

Indications

  1. bronchitis
  2. common cold
  3. cough
  4. nasal congestion

For the temporary relief of non-productive cough and nasal congestion as may occur with the common cold, influenza, sinusitis, or bronchitis

Side Effects

  1. abdominal pain
  2. anxiety
  3. apnea
  4. bradycardia
  5. confusion
  6. contact dermatitis
  7. diarrhea
  8. dizziness
  9. drowsiness
  10. dysuria
  11. hallucinations
  12. headache
  13. hypertension
  14. hypotension
  15. hypotonia
  16. insomnia
  17. leukopenia
  18. nausea
  19. nephrolithiasis
  20. pallor
  21. rash
  22. respiratory depression
  23. restlessness
  24. seizures
  25. tremor
  26. urinary retention
  27. vomiting
  28. weakness

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • acute myocardial infarction
  • angina
  • arteriosclerosis
  • asthma
  • atrial fibrillation
  • atrial flutter
  • AV block
  • bradycardia
  • breast-feeding
  • bronchitis
  • bundle-branch block
  • cardiac arrhythmias
  • cardiac disease
  • cardiomyopathy
  • children
  • closed-angle glaucoma
  • coronary artery disease
  • diabetes mellitus
  • driving or operating machinery
  • emphysema
  • fever
  • geriatric
  • head trauma
  • headache
  • heart failure
  • hepatic disease
  • hypertension
  • hyperthyroidism
  • increased intracranial pressure
  • infants
  • labor
  • MAOI therapy
  • myocardial infarction
  • neonates
  • obstetric delivery
  • peripheral vascular disease
  • pregnancy
  • prostatic hypertrophy
  • seizure disorder
  • seizures
  • tobacco smoking
  • urinary retention
  • ventricular fibrillation
  • ventricular tachycardia
  • vomiting

Interactions

  • Acarbose
  • Acebutolol
  • Acetaminophen; Aspirin, ASA; Caffeine
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
  • Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
  • Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Dextromethorphan; Pseudoephedrine
  • Acetaminophen; Pseudoephedrine
  • Acetaminophen; Tramadol
  • Aclidinium; Formoterol
  • Acrivastine; Pseudoephedrine
  • Albiglutide
  • Albuterol
  • Albuterol; Ipratropium
  • Aliskiren; Amlodipine
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Alogliptin; Metformin
  • Alogliptin; Pioglitazone
  • Alpha-blockers
  • Alpha-glucosidase Inhibitors
  • Alprazolam
  • Ambrisentan
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Amiodarone
  • Amitriptyline; Chlordiazepoxide
  • Amlodipine
  • Amlodipine; Atorvastatin
  • Amlodipine; Benazepril
  • Amlodipine; Celecoxib
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amlodipine; Olmesartan
  • Amlodipine; Telmisartan
  • Amlodipine; Valsartan
  • Amoxapine
  • Angiotensin II receptor antagonists
  • Angiotensin-converting enzyme inhibitors
  • Anticholinergics
  • Anxiolytics; Sedatives; and Hypnotics
  • Arformoterol
  • Articaine; Epinephrine
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Atenolol
  • Atenolol; Chlorthalidone
  • Atomoxetine
  • Atropine
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Edrophonium
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • atypical antipsychotic
  • Avanafil
  • Azelastine; Fluticasone
  • Azilsartan; Chlorthalidone
  • Baloxavir Marboxil
  • Barbiturates
  • Beclomethasone
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Bendroflumethiazide; Nadolol
  • Benzodiazepines
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benztropine
  • Beta-blockers
  • Betamethasone
  • Betaxolol
  • Bethanechol
  • Bisoprolol
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Bosentan
  • Bretylium
  • Brimonidine; Timolol
  • Bromocriptine
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Brompheniramine; Pseudoephedrine
  • Budesonide
  • Budesonide; Formoterol
  • Bumetanide
  • Buspirone
  • Butorphanol
  • Butyrophenone
  • Caffeine
  • Caffeine; Ergotamine
  • Calcium-channel blockers
  • Canagliflozin
  • Canagliflozin; Metformin
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Captopril; Hydrochlorothiazide, HCTZ
  • Carbetapentane; Pseudoephedrine
  • Carbinoxamine; Dextromethorphan; Pseudoephedrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carbinoxamine; Pseudoephedrine
  • Cardiac glycosides
  • Carteolol
  • Carvedilol
  • Cephalexin
  • Cetirizine; Pseudoephedrine
  • Chlophedianol; Dexchlorpheniramine; Pseudoephedrine
  • Chlordiazepoxide
  • Chlordiazepoxide; Clidinium
  • Chlorothiazide
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Pseudoephedrine
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Ciclesonide
  • Ciprofloxacin
  • Clevidipine
  • Clonazepam
  • Clonidine
  • Clorazepate
  • Cocaine
  • Colchicine
  • Colchicine; Probenecid
  • COMT inhibitors
  • Corticosteroids
  • Cortisone
  • Dapagliflozin
  • Dapagliflozin; Metformin
  • Dapagliflozin; Saxagliptin
  • Deferiprone
  • Deflazacort
  • Delafloxacin
  • Desloratadine; Pseudoephedrine
  • Desmopressin
  • Dexamethasone
  • Dexchlorpheniramine; Dextromethorphan; Pseudoephedrine
  • Dexmethylphenidate
  • Dextromethorphan; Guaifenesin; Pseudoephedrine
  • Diazepam
  • Dicyclomine
  • Diethylpropion
  • Digitoxin
  • Digoxin
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Dihydroergotamine
  • Diltiazem
  • Dipeptidyl Peptidase-4 Inhibitors
  • Dorzolamide; Timolol
  • Doxazosin
  • Dronabinol
  • Dulaglutide
  • Dyphylline
  • Dyphylline; Guaifenesin
  • Edetate Calcium Disodium, Calcium EDTA
  • Edetate Disodium, Disodium EDTA
  • Eltrombopag
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Enflurane
  • enteral feedings
  • Epinephrine
  • Epoprostenol
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Ergoloid Mesylates
  • Ergonovine
  • Ergot alkaloids
  • Ergotamine
  • Ertugliflozin
  • Ertugliflozin; Metformin
  • Ertugliflozin; Sitagliptin
  • Esmolol
  • Estazolam
  • Ethacrynic Acid
  • Ethanol
  • Ethinyl Estradiol; Norethindrone Acetate; Ferrous fumarate
  • Ethinyl Estradiol; Norethindrone; Ferrous fumarate
  • Exenatide
  • Felodipine
  • Fentanyl
  • Fexofenadine; Pseudoephedrine
  • Flavoxate
  • Fludrocortisone
  • Flunisolide
  • Flurazepam
  • Fluticasone
  • Fluticasone; Salmeterol
  • Fluticasone; Umeclidinium; Vilanterol
  • Fluticasone; Vilanterol
  • food
  • Formoterol
  • Formoterol; Mometasone
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Furosemide
  • Gemifloxacin
  • General anesthetics
  • Ginger, Zingiber officinale
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glipizide; Metformin
  • Glyburide; Metformin
  • Glycopyrrolate
  • Glycopyrrolate; Formoterol
  • Green Tea
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Guaifenesin; Pseudoephedrine
  • Guanabenz
  • Haloperidol
  • Halothane
  • Heterocyclic antidepressants
  • Homatropine; Hydrocodone
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydrocortisone
  • Hyoscyamine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibuprofen; Pseudoephedrine
  • Iloprost
  • Incretin Mimetics
  • Indacaterol
  • Indacaterol; Glycopyrrolate
  • Indapamide
  • Insulin Degludec; Liraglutide
  • Insulin Glargine; Lixisenatide
  • Insulins
  • Iobenguane I 131
  • Ionic Contrast Media
  • Iron
  • Iron Salts
  • Isocarboxazid
  • Isoflurane
  • Isradipine
  • Labetalol
  • Levalbuterol
  • Levobetaxolol
  • Levobunolol
  • Levofloxacin
  • Levothyroxine
  • Levothyroxine; Liothyronine (Porcine)
  • Levothyroxine; Liothyronine (Synthetic)
  • Linagliptin; Metformin
  • Linezolid
  • Liothyronine
  • Liraglutide
  • Lixisenatide
  • Loop diuretics
  • Loratadine; Pseudoephedrine
  • Lorazepam
  • Loxapine
  • Macitentan
  • Maprotiline
  • Mecamylamine
  • Meglitinides
  • Mepenzolate
  • Metaproterenol
  • Metformin
  • Metformin; Pioglitazone
  • Metformin; Repaglinide
  • Metformin; Rosiglitazone
  • Metformin; Saxagliptin
  • Metformin; Sitagliptin
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methocarbamol
  • Methscopolamine
  • Methyclothiazide
  • Methyldopa
  • Methylergonovine
  • Methylphenidate
  • Methylprednisolone
  • Methysergide
  • Metolazone
  • Metoprolol
  • Midazolam
  • Midodrine
  • Miglitol
  • Minocycline
  • Molindone
  • Mometasone
  • Monoamine oxidase inhibitors
  • Moxifloxacin
  • Nabilone
  • Nadolol
  • Nafarelin
  • Naproxen; Pseudoephedrine
  • Nebivolol
  • Nebivolol; Valsartan
  • Nefazodone
  • Nicardipine
  • Nicotine
  • Nifedipine
  • Nimodipine
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  • Nitrates
  • Non-Ionic Contrast Media
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  • Opiate Agonists
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  • Oxazepam
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  • Ozanimod
  • Penbutolol
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  • Perindopril; Amlodipine
  • Phendimetrazine
  • Phenelzine
  • Phenothiazines
  • Phenoxybenzamine
  • Phentermine
  • Phentermine; Topiramate
  • Phentolamine
  • Phosphodiesterase inhibitors
  • Phosphorus
  • Pimozide
  • Pindolol
  • Pioglitazone
  • Pirbuterol
  • Polysaccharide-Iron Complex
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  • Pramipexole
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  • Prazosin
  • Prednisolone
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  • Pregabalin
  • Prilocaine; Epinephrine
  • Procarbazine
  • Propantheline
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  • Pseudoephedrine
  • Quazepam
  • Racepinephrine
  • Rasagiline
  • Reserpine
  • Riociguat
  • Ropinirole
  • Rosiglitazone
  • Safinamide
  • Salmeterol
  • Scopolamine
  • Sedating H1-blockers
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  • Tadalafil
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  • Tetracyclines
  • Theophylline, Aminophylline
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  • Thyroid hormones
  • Timolol
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  • Trospium
  • Umeclidinium; Vilanterol
  • Vardenafil
  • Vasodilators
  • Verapamil
  • Yohimbine
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