Carbetapentane Chlorpheniramine Phenylephrine

Carbetapentane Chlorpheniramine Phenylephrine Brand Names

Carbaphen-12 | Carbaphen-12 Ped | Exratuss | Ricotuss | Tannate 12 | Tannic-12 | Tannihist-12 | Trionate Pediatric | Tussi-12 | Xiratuss

What is Carbetapentane Chlorpheniramine Phenylephrine

NOTE: These products are discontinued in the U.S.

Carbetapentane chlorpheniramine phenylephrine are used together for the relief of cough, nasal congestion, and rhinorrhea associated with the common cold, asthma, bronchitis, or other upper respiratory tract conditions.

Carbetapentane is a non-opioid, centrally acting cough suppressant.

The cough suppressant effect of carbetapentane is less potent than opiates; however, unlike opiates, carbetapentane has not been associated with substance abuse.

Chlorpheniramine is a first generation sedating antihistamine (H1-blocker) of the propylamine class commonly used for treating symptoms related to histamine release such as rhinorrhea.

Antihistamines from the propylamine group, such as chlorpheniramine, generally have a more potent antihistamine effect and less sedation and antiemetic effects than antihistamines from the ethanolamine group (e.g., diphenhydramine).

Phenylephrine is a sympathomimetic amine used as a decongestant to decrease nasal and sinus congestion.

Carbetapentane chlorpheniramine phenylephrine is available by prescription in solid and liquid preparations.

Indications

1. asthma
2. bronchitis
3. common cold
4. cough
5. nasal congestion
6. rhinorrhea

For relief of cough, nasal congestion, and rhinorrhea associated with the common cold, asthma, bronchitis, or other upper respiratory tract conditions

Side Effects

1. abdominal pain
2. angina
3. anorexia
4. anxiety
5. apnea
6. arrhythmia exacerbation
7. ataxia
8. blurred vision
9. bronchial secretions
10. constipation
11. diarrhea
12. diplopia
13. dizziness
14. drowsiness
15. dyspepsia
16. dysuria
17. excitability
18. hallucinations
19. headache
20. hypertension
21. hypertensive crisis
22. hyperthermia
23. hypotension
24. hypotonia
25. insomnia
26. irritability
27. leukopenia
28. mydriasis
29. myocardial infarction
30. nausea
31. pallor
32. palpitations
33. photophobia
34. photosensitivity
35. polyuria
36. premature ventricular contractions (PVCs)
37. pruritus
38. psychosis
39. rash
40. respiratory depression
41. restlessness
42. seizures
43. sinus tachycardia
44. stroke
45. supraventricular tachycardia (SVT)
46. urinary retention
47. urticaria
48. visual impairment
49. vomiting
50. wheezing
51. xerophthalmia
52. xerostomia

Monitoring Parameters

• laboratory monitoring not necessary

Contraindications

• acute myocardial infarction
• aneurysm
• angina
• anticholinergic medications
• arteriosclerosis
• asthma
• atrial fibrillation
• atrial flutter
• AV block
• bladder obstruction
• bradycardia
• breast-feeding
• bronchitis
• bundle-branch block
• cardiac arrhythmias
• cardiac disease
• cardiomyopathy
• cerebrovascular disease
• children
• chronic obstructive pulmonary disease (COPD)
• closed-angle glaucoma
• constipation
• contact lenses
• coronary artery disease
• diabetes mellitus
• driving or operating machinery
• emphysema
• geriatric
• GI disease
• GI obstruction
• head trauma
• heart failure
• hepatic disease
• hypertension
• hyperthyroidism
• ileus
• increased intracranial pressure
• increased intraocular pressure
• infants
• intracranial bleeding
• labor
• MAOI therapy
• myocardial infarction
• neonates
• obstetric delivery
• organic brain syndrome
• peptic ulcer disease
• peripheral vascular disease
• pregnancy
• prostatic hypertrophy
• pulmonary disease
• pyloric stenosis
• renal disease
• renal failure
• renal impairment
• seizure disorder
• seizures
• status asthmaticus
• stroke
• tachycardia
• thyrotoxicosis
• tobacco smoking
• ulcerative colitis
• urinary retention
• ventricular fibrillation
• ventricular tachycardia

Interactions

• Acarbose
• Acebutolol
• Acetaminophen; Aspirin, ASA; Caffeine
• Acetaminophen; Butalbital
• Acetaminophen; Butalbital; Caffeine
• Acetaminophen; Butalbital; Caffeine; Codeine
• Acetaminophen; Caffeine
• Acetaminophen; Caffeine; Dihydrocodeine
• Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
• Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
• Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Codeine
• Acetaminophen; Dextromethorphan; Pseudoephedrine
• Acetaminophen; Dichloralphenazone; Isometheptene
• Acetaminophen; Hydrocodone
• Acetaminophen; Oxycodone
• Acetaminophen; Pentazocine
• Acetaminophen; Propoxyphene
• Acetaminophen; Pseudoephedrine
• Acetaminophen; Tramadol
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• Acrivastine; Pseudoephedrine
• Albiglutide
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• Alogliptin; Metformin
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• Amlodipine; Celecoxib
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• Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
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• Aspirin, ASA; Caffeine; Orphenadrine
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• Empagliflozin; Linagliptin
• Empagliflozin; Linagliptin; Metformin
• Empagliflozin; Metformin
• Enalapril; Felodipine
• Enalapril; Hydrochlorothiazide, HCTZ
• Enflurane
• Entacapone
• Epinephrine
• Epoprostenol
• Eprosartan; Hydrochlorothiazide, HCTZ
• Ergoloid Mesylates
• Ergonovine
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• Ertugliflozin; Metformin
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• Esketamine
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• Glycopyrrolate
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• Green Tea
• Guaifenesin; Hydrocodone
• Guaifenesin; Hydrocodone; Pseudoephedrine
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• Guanabenz
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• Hydrochlorothiazide, HCTZ; Olmesartan
• Hydrochlorothiazide, HCTZ; Propranolol
• Hydrochlorothiazide, HCTZ; Quinapril
• Hydrochlorothiazide, HCTZ; Spironolactone
• Hydrochlorothiazide, HCTZ; Telmisartan
• Hydrochlorothiazide, HCTZ; Triamterene
• Hydrochlorothiazide, HCTZ; Valsartan
• Hydrocodone
• Hydrocodone; Ibuprofen
• Hydrocodone; Phenylephrine
• Hydrocodone; Potassium Guaiacolsulfonate
• Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
• Hydrocodone; Pseudoephedrine
• Hydrocortisone
• Hydromorphone
• Hyoscyamine
• Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
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