Carbetapentane Chlorpheniramine

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Carbetapentane Chlorpheniramine Brand Names

C Tanna-12 | Ricotuss H | Tannate 12 S | Tannic-12 | Tannic-12 S | Tannihist-12 RF | Trionate | Tussi-12 | Tussi-12 S | Tussizone-12 RF | Tustan 12S

What is Carbetapentane Chlorpheniramine

NOTE: These products are discontinued in the U.S.

Carbetapentane chlorpheniramine is an antitussive-antihistamine combination product.

Carbetapentane and chlorpheniramine are used together in an oral preparation to relieve cough and histamine-mediated allergic symptoms, such as congestion, rhinorrhea, sneezing, and watery, itchy eyes.

Specifically, this combination is indicated for the relief of such symptoms due to the common cold, bronchial asthma, and acute and chronic bronchitis.

Carbetapentane is a non-opioid, centrally acting cough suppressant.

Carbetapentane suppresses the cough reflex by direct action on the medullary cough center and also produces a drying effect on the respiratory mucus membranes.

Chlorpheniramine is a sedating antihistamine (H1-blocker) that dries nasal and sinus passages secondary to its anticholinergic activity.

Chlorpheniramine is similar in structure to brompheniramine, but is associated with less sedation.

Carbetapentane chlorpheniramine combination products are dosed twice daily and are available as oral tablets and liquids.

Indications

  1. bronchitis
  2. common cold
  3. cough
  4. rhinorrhea
  5. sneezing

For the relief of cough, rhinorrhea, sneezing, and itchy, watery eyes associated with the common cold, bronchial asthma, and acute and chronic bronchitis

Side Effects

  1. abdominal pain
  2. agranulocytosis
  3. aplastic anemia
  4. ataxia
  5. blurred vision
  6. confusion
  7. constipation
  8. dizziness
  9. drowsiness
  10. hallucinations
  11. headache
  12. hypertension
  13. hypotension
  14. impaired cognition
  15. insomnia
  16. mydriasis
  17. nausea
  18. palpitations
  19. psychosis
  20. restlessness
  21. seizures
  22. sinus tachycardia
  23. thrombocytopenia
  24. urinary retention
  25. vomiting
  26. weakness
  27. xerophthalmia
  28. xerostomia

Monitoring Parameters

  • laboratory monitoring not necessary

Contraindications

  • anticholinergic medications
  • asthma
  • bladder obstruction
  • breast-feeding
  • bronchitis
  • cardiac disease
  • cardiomyopathy
  • children
  • closed-angle glaucoma
  • contact lenses
  • driving or operating machinery
  • emphysema
  • geriatric
  • GI obstruction
  • head trauma
  • heart failure
  • hepatic disease
  • hypertension
  • ileus
  • increased intracranial pressure
  • infants
  • neonates
  • peptic ulcer disease
  • pregnancy
  • prostatic hypertrophy
  • tartrazine dye hypersensitivity
  • tobacco smoking
  • urinary retention

Interactions

  • Acetaminophen; Butalbital
  • Acetaminophen; Butalbital; Caffeine
  • Acetaminophen; Butalbital; Caffeine; Codeine
  • Acetaminophen; Caffeine; Dihydrocodeine
  • Acetaminophen; Codeine
  • Acetaminophen; Dichloralphenazone; Isometheptene
  • Acetaminophen; Hydrocodone
  • Acetaminophen; Oxycodone
  • Acetaminophen; Pentazocine
  • Acetaminophen; Propoxyphene
  • Acetaminophen; Tramadol
  • Alfentanil
  • Alosetron
  • Amantadine
  • Ambenonium Chloride
  • Amikacin
  • Aminoglycosides
  • Amlodipine; Celecoxib
  • Amobarbital
  • Amoxapine
  • Amphetamine
  • Amphetamine; Dextroamphetamine
  • Amphetamine; Dextroamphetamine Salts
  • Anticholinergics
  • Anxiolytics; Sedatives; and Hypnotics
  • Apomorphine
  • Artemether; Lumefantrine
  • Asenapine
  • Aspirin, ASA; Butalbital; Caffeine
  • Aspirin, ASA; Butalbital; Caffeine; Codeine
  • Aspirin, ASA; Caffeine; Dihydrocodeine
  • Aspirin, ASA; Caffeine; Orphenadrine
  • Aspirin, ASA; Carisoprodol
  • Aspirin, ASA; Carisoprodol; Codeine
  • Aspirin, ASA; Oxycodone
  • Atazanavir; Cobicistat
  • Atropine
  • Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Atropine; Difenoxin
  • Atropine; Diphenoxylate
  • Atropine; Edrophonium
  • Atropine; Hyoscyamine; Phenobarbital; Scopolamine
  • atypical antipsychotic
  • Azelastine
  • Azelastine; Fluticasone
  • Baclofen
  • Barbiturates
  • Belladonna Alkaloids; Ergotamine; Phenobarbital
  • Belladonna; Opium
  • Benzhydrocodone; Acetaminophen
  • Benzodiazepines
  • Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
  • Benzphetamine
  • Benztropine
  • Brompheniramine; Carbetapentane; Phenylephrine
  • Brompheniramine; Guaifenesin; Hydrocodone
  • Brompheniramine; Hydrocodone; Pseudoephedrine
  • Buprenorphine
  • Buprenorphine; Naloxone
  • Buspirone
  • Butabarbital
  • Butorphanol
  • Butyrophenone
  • Cannabidiol
  • Capsaicin; Metaxalone
  • Carbetapentane; Chlorpheniramine; Phenylephrine
  • Carbetapentane; Diphenhydramine; Phenylephrine
  • Carbetapentane; Guaifenesin
  • Carbetapentane; Guaifenesin; Phenylephrine
  • Carbetapentane; Phenylephrine
  • Carbetapentane; Phenylephrine; Pyrilamine
  • Carbetapentane; Pseudoephedrine
  • Carbetapentane; Pyrilamine
  • Carbidopa; Levodopa; Entacapone
  • Carbinoxamine; Hydrocodone; Phenylephrine
  • Carbinoxamine; Hydrocodone; Pseudoephedrine
  • Carisoprodol
  • Celecoxib
  • Cenobamate
  • Cetirizine
  • Cetirizine; Pseudoephedrine
  • Chlordiazepoxide; Clidinium
  • Chlorpheniramine; Codeine
  • Chlorpheniramine; Dihydrocodeine; Phenylephrine
  • Chlorpheniramine; Dihydrocodeine; Pseudoephedrine
  • Chlorpheniramine; Guaifenesin; Hydrocodone; Pseudoephedrine
  • Chlorpheniramine; Hydrocodone
  • Chlorpheniramine; Hydrocodone; Phenylephrine
  • Chlorpheniramine; Hydrocodone; Pseudoephedrine
  • Chlorpromazine
  • Chlorzoxazone
  • Clobazam
  • Clozapine
  • Cobicistat
  • Codeine
  • Codeine; Guaifenesin
  • Codeine; Phenylephrine; Promethazine
  • Codeine; Promethazine
  • COMT inhibitors
  • Cyclobenzaprine
  • Dantrolene
  • Daratumumab; Hyaluronidase
  • Darunavir; Cobicistat
  • Darunavir; Cobicistat; Emtricitabine; Tenofovir alafenamide
  • Dasabuvir; Ombitasvir; Paritaprevir; Ritonavir
  • Desloratadine
  • Desloratadine; Pseudoephedrine
  • Deutetrabenazine
  • Dexmedetomidine
  • Dextroamphetamine
  • Dextromethorphan; Promethazine
  • Dicyclomine
  • Dihydrocodeine; Guaifenesin; Pseudoephedrine
  • Diphenhydramine; Hydrocodone; Phenylephrine
  • Disopyramide
  • Donepezil
  • Donepezil; Memantine
  • Doxorubicin
  • Dronabinol
  • Dronedarone
  • Droperidol
  • Dutasteride; Tamsulosin
  • Eliglustat
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Alafenamide
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Entacapone
  • Esketamine
  • Eszopiclone
  • Ethanol
  • Etomidate
  • Ezogabine
  • Fentanyl
  • Flavoxate
  • Flibanserin
  • Fluoxetine; Olanzapine
  • Fluphenazine
  • Fospropofol
  • Gabapentin
  • Galantamine
  • General anesthetics
  • Gentamicin
  • Glycopyrrolate
  • Glycopyrrolate; Formoterol
  • Guaifenesin; Hydrocodone
  • Guaifenesin; Hydrocodone; Pseudoephedrine
  • Halogenated Anesthetics
  • Haloperidol
  • Heparin
  • Heterocyclic antidepressants
  • Homatropine; Hydrocodone
  • Hyaluronidase
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydantoins
  • Hydrocodone
  • Hydrocodone; Ibuprofen
  • Hydrocodone; Phenylephrine
  • Hydrocodone; Potassium Guaiacolsulfonate
  • Hydrocodone; Potassium Guaiacolsulfonate; Pseudoephedrine
  • Hydrocodone; Pseudoephedrine
  • Hydromorphone
  • Hyoscyamine
  • Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
  • Ibuprofen; Oxycodone
  • Iloperidone
  • Indacaterol; Glycopyrrolate
  • Isocarboxazid
  • Kanamycin
  • Ketamine
  • Lasmiditan
  • Lemborexant
  • Levocetirizine
  • Levomethadyl
  • Levorphanol
  • Linezolid
  • Lithium
  • Lofexidine
  • Loperamide
  • Loperamide; Simethicone
  • Lopinavir; Ritonavir
  • Loratadine
  • Loratadine; Pseudoephedrine
  • Loxapine
  • Lumateperone
  • Lurasidone
  • Magnesium Salts
  • Maprotiline
  • Meclizine
  • Melatonin
  • Mepenzolate
  • Meperidine
  • Meperidine; Promethazine
  • Mephobarbital
  • Meprobamate
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methenamine; Sodium Acid Phosphate; Methylene Blue; Hyoscyamine
  • Methocarbamol
  • Methohexital
  • Methscopolamine
  • Metoclopramide
  • Metyrapone
  • Metyrosine
  • Minocycline
  • Mirabegron
  • Mirtazapine
  • Mitotane
  • Molindone
  • Monoamine oxidase inhibitors
  • Morphine
  • Morphine; Naltrexone
  • Nabilone
  • Nalbuphine
  • Nebivolol
  • Nebivolol; Valsartan
  • Nefazodone
  • Olanzapine
  • Ombitasvir; Paritaprevir; Ritonavir
  • Opiate Agonists
  • Opiate Agonists-Antagonists
  • Oritavancin
  • Orphenadrine
  • Oxybutynin
  • Oxycodone
  • Oxymorphone
  • Paliperidone
  • Paromomycin
  • Paroxetine
  • Peginterferon Alfa-2b
  • Pentazocine
  • Pentazocine; Naloxone
  • Pentobarbital
  • Perampanel
  • Perphenazine
  • Perphenazine; Amitriptyline
  • Phenelzine
  • Phenobarbital
  • Phenothiazines
  • Phenylephrine; Promethazine
  • Pimozide
  • Pitolisant
  • Plazomicin
  • Pramipexole
  • Pregabalin
  • Primidone
  • Procarbazine
  • Prochlorperazine
  • Promethazine
  • Propantheline
  • Propofol
  • Propoxyphene
  • Quetiapine
  • Ramelteon
  • Rasagiline
  • Remifentanil
  • Risperidone
  • Ritonavir
  • Rituximab; Hyaluronidase
  • Rivastigmine
  • Rolapitant
  • Ropinirole
  • Safinamide
  • Scopolamine
  • Secobarbital
  • Sedating H1-blockers
  • Selegiline
  • Sincalide
  • Skeletal Muscle Relaxants
  • Sodium Iodide
  • Solifenacin
  • Streptomycin
  • Sufentanil
  • Suvorexant
  • Tacrine
  • Tamsulosin
  • Tapentadol
  • Tasimelteon
  • Thalidomide
  • Thiopental
  • Thioridazine
  • Thiothixene
  • Tizanidine
  • Tobramycin
  • Tolcapone
  • Tramadol
  • Tranylcypromine
  • Trastuzumab; Hyaluronidase
  • Trazodone
  • Tricyclic antidepressants
  • Trifluoperazine
  • Trihexyphenidyl
  • Trimethobenzamide
  • Trospium
  • Vemurafenib
  • Vigabatrin
  • Vilazodone
  • Zaleplon
  • Ziconotide
  • Ziprasidone
  • Zolpidem

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