Brompheniramine Guaifenesin Hydrocodone Brand Name– Tusnel HC
What is Brompheniramine Guaifenesin Hydrocodone
NOTE: This product is discontinued in the U.S.
Brompheniramine guaifenesin hydrocodone are used together in oral preparations to relieve symptoms associated with allergic rhinitis, the common cold or other minor throat or bronchial irritants.
These symptoms include cough, rhinorrhea, sneezing, and watery eyes.
Brompheniramine is a first-generation sedating antihistamine (H1-blocker) of the propylamine class. It dries the nasal and sinus passages secondary to its anticholinergic activity.
Guaifenesin loosens and thins phlegm and bronchial secretions to ease expectoration.
Although guaifenesin may be used as an expectorant in both productive and non-productive coughs, it is especially useful in the treatment of dry, non-productive coughs which tend to injure the respiratory mucous membranes.
Hydrocodone is an opiate agonist and is included for its antitussive effects.
Indications
- allergic rhinitis
- common cold
- cough
- rhinorrhea
- sneezing
Side Effects
- abdominal pain
- anorexia
- anxiety
- blurred vision
- constipation
- delirium
- diarrhea
- diplopia
- dizziness
- drowsiness
- dyskinesia
- dyspepsia
- dysphoria
- dysuria
- emotional lability
- euphoria
- excitability
- headache
- hypertension
- hypotension
- impotence (erectile dysfunction)
- insomnia
- irritability
- lethargy
- nausea
- nephrolithiasis
- palpitations
- photophobia
- pruritus
- psychological dependence
- rash
- respiratory depression
- restlessness
- seizures
- sinus tachycardia
- tinnitus
- tolerance
- tremor
- urinary retention
- urticaria
- vertigo
- visual impairment
- vomiting
- weakness
- withdrawal
- xerophthalmia
- xerostomia
Monitoring Parameters
- laboratory monitoring not necessary
Contraindications
- abrupt discontinuation
- asthma
- bladder obstruction
- breast-feeding
- bronchitis
- cardiac disease
- children
- chronic obstructive pulmonary disease (COPD)
- closed-angle glaucoma
- constipation
- contact lenses
- diabetes mellitus
- diarrhea
- driving or operating machinery
- edema
- emphysema
- geriatric
- GI obstruction
- head trauma
- heart failure
- hepatic disease
- hypertension
- ileus
- increased intracranial pressure
- infants
- labor
- neonates
- opiate agonist hypersensitivity
- peptic ulcer disease
- pregnancy
- prostatic hypertrophy
- renal disease
- renal failure
- renal impairment
- sepsis
- substance abuse
- systemic lupus erythematosus (SLE)
- tobacco smoking
- ulcerative colitis
- urethral stricture
- urinary retention
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