Aminosalicylate sodium and Aminosalicylic acid

Aminosalicylate sodium and Aminosalicylic acid Brand Name– PASER

What is Aminosalicylate sodium and Aminosalicylic acid

Aminosalicylate sodium and aminosalicylic acid are analogs of aminobenzoic acid (PABA) and are used orally as antituberculosis agents.

They are administered as adjunct agents in combination with at least one other antituberculosis agent.

Aminosalicylate sodium and aminosalicylic acid are usually reserved as last-line agents secondary to effectiveness.

Aminosalicylate sodium was approved prior to 1982 and aminosalicylic acid was approved in 1994.

Indications

  1. aminosalicylic acid desensitization
  2. Mycobacterium tuberculosis
  3. tuberculosis infection

Side Effects

  1. abdominal pain
  2. agranulocytosis
  3. crystalluria
  4. diarrhea
  5. encephalopathy
  6. exfoliative dermatitis
  7. fever
  8. hemolytic anemia
  9. hepatitis
  10. hypoglycemia
  11. jaundice
  12. leukopenia
  13. nausea
  14. optic neuritis
  15. pericarditis
  16. thrombocytopenia
  17. vasculitis
  18. vomiting

Monitoring Parameters

  • serum creatinine/BUN

Contraindications

  • breast-feeding
  • hepatic disease
  • hepatitis
  • jaundice
  • malabsorption syndrome
  • pregnancy
  • renal disease
  • renal failure
  • vitamin B12 deficiency

Interactions

  • Acetazolamide
  • Aliskiren; Amlodipine; Hydrochlorothiazide, HCTZ
  • Aliskiren; Hydrochlorothiazide, HCTZ
  • Alogliptin
  • Alogliptin; Metformin
  • Alogliptin; Pioglitazone
  • Alpha-glucosidase Inhibitors
  • Amiloride
  • Amiloride; Hydrochlorothiazide, HCTZ
  • Aminoglycosides
  • Amlodipine; Benazepril
  • Amlodipine; Hydrochlorothiazide, HCTZ; Olmesartan
  • Amlodipine; Hydrochlorothiazide, HCTZ; Valsartan
  • Amphotericin B
  • Amphotericin B cholesteryl sulfate complex (ABCD)
  • Amphotericin B lipid complex (ABLC)
  • Amphotericin B liposomal (LAmB)
  • Angiotensin-converting enzyme inhibitors
  • Antithrombin III
  • Antithymocyte Globulin
  • Apixaban
  • Ardeparin
  • Articaine; Epinephrine
  • Atenolol; Chlorthalidone
  • Azilsartan; Chlorthalidone
  • Bacitracin
  • Barbiturates
  • Benazepril
  • Benazepril; Hydrochlorothiazide, HCTZ
  • Bendroflumethiazide; Nadolol
  • Bisoprolol; Hydrochlorothiazide, HCTZ
  • Bromocriptine
  • Bumetanide
  • Bupivacaine
  • Bupivacaine Liposomal
  • Bupivacaine; Lidocaine
  • Calcium Carbonate
  • Calcium Carbonate; Magnesium Hydroxide
  • Calcium Carbonate; Risedronate
  • Calcium Carbonate; Simethicone
  • Canagliflozin
  • Canagliflozin; Metformin
  • Candesartan; Hydrochlorothiazide, HCTZ
  • Capreomycin
  • Captopril
  • Captopril; Hydrochlorothiazide, HCTZ
  • Cefixime
  • Cefotetan
  • Chloroprocaine
  • Chlorothiazide
  • Chlorthalidone
  • Chlorthalidone; Clonidine
  • Citric Acid; Potassium Citrate
  • Citric Acid; Potassium Citrate; Sodium Citrate
  • Colchicine; Probenecid
  • Colistimethate, Colistin, Polymyxin E
  • Corticosteroids
  • Cyclosporine
  • Dabigatran
  • Dalteparin
  • Dapagliflozin
  • Dapagliflozin; Metformin
  • Dapagliflozin; Saxagliptin
  • Daratumumab; Hyaluronidase
  • Deferasirox
  • Diclofenac
  • Diclofenac; Misoprostol
  • Diflunisal
  • Diphenhydramine; Ibuprofen
  • Diphenhydramine; Naproxen
  • Doravirine; Lamivudine; Tenofovir disoproxil fumarate
  • Drotrecogin Alfa
  • Edoxaban
  • Efavirenz; Emtricitabine; Tenofovir
  • Efavirenz; Lamivudine; Tenofovir Disoproxil Fumarate
  • Elvitegravir; Cobicistat; Emtricitabine; Tenofovir Disoproxil Fumarate
  • Empagliflozin
  • Empagliflozin; Linagliptin
  • Empagliflozin; Linagliptin; Metformin
  • Empagliflozin; Metformin
  • Emtricitabine; Rilpivirine; Tenofovir disoproxil fumarate
  • Emtricitabine; Tenofovir disoproxil fumarate
  • Enalapril, Enalaprilat
  • Enalapril; Felodipine
  • Enalapril; Hydrochlorothiazide, HCTZ
  • Enoxaparin
  • Eprosartan; Hydrochlorothiazide, HCTZ
  • Ertugliflozin; Metformin
  • Ertugliflozin; Sitagliptin
  • Esomeprazole; Naproxen
  • Ethacrynic Acid
  • Ethambutol
  • Ethanol
  • Ethionamide
  • Ethotoin
  • Etodolac
  • Famotidine; Ibuprofen
  • Fenoprofen
  • Flurbiprofen
  • Fondaparinux
  • Foscarnet
  • Fosinopril
  • Fosinopril; Hydrochlorothiazide, HCTZ
  • Fosphenytoin
  • Furosemide
  • Gallium Ga 68 Dotatate
  • Glimepiride; Pioglitazone
  • Glimepiride; Rosiglitazone
  • Glipizide; Metformin
  • Glyburide; Metformin
  • Griseofulvin
  • Heparin
  • Hyaluronidase
  • Hyaluronidase, Recombinant; Immune Globulin
  • Hydralazine; Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ
  • Hydrochlorothiazide, HCTZ; Irbesartan
  • Hydrochlorothiazide, HCTZ; Lisinopril
  • Hydrochlorothiazide, HCTZ; Losartan
  • Hydrochlorothiazide, HCTZ; Methyldopa
  • Hydrochlorothiazide, HCTZ; Metoprolol
  • Hydrochlorothiazide, HCTZ; Moexipril
  • Hydrochlorothiazide, HCTZ; Olmesartan
  • Hydrochlorothiazide, HCTZ; Propranolol
  • Hydrochlorothiazide, HCTZ; Quinapril
  • Hydrochlorothiazide, HCTZ; Spironolactone
  • Hydrochlorothiazide, HCTZ; Telmisartan
  • Hydrochlorothiazide, HCTZ; Triamterene
  • Hydrochlorothiazide, HCTZ; Valsartan
  • Hydrocodone; Ibuprofen
  • Ibuprofen
  • Ibuprofen; Oxycodone
  • Ibuprofen; Pseudoephedrine
  • Incretin Mimetics
  • Indapamide
  • Inotersen
  • Insulins
  • Isoniazid, INH
  • Isoniazid, INH; Pyrazinamide, PZA; Rifampin
  • Isoniazid, INH; Rifampin
  • Ketoprofen
  • Ketorolac
  • Lamivudine; Tenofovir Disoproxil Fumarate
  • Lansoprazole; Naproxen
  • Lidocaine
  • Lidocaine; Prilocaine
  • Linagliptin
  • Linagliptin; Metformin
  • Lisinopril
  • Loop diuretics
  • Low Molecular Weight Heparins
  • Macimorelin
  • Mannitol
  • Measles Virus; Mumps Virus; Rubella Virus; Varicella Virus Vaccine, Live
  • Meclofenamate Sodium
  • Mefenamic Acid
  • Meglitinides
  • Meloxicam
  • Mepivacaine
  • Mepivacaine; Levonordefrin
  • Metformin
  • Metformin; Pioglitazone
  • Metformin; Repaglinide
  • Metformin; Rosiglitazone
  • Metformin; Saxagliptin
  • Metformin; Sitagliptin
  • Methazolamide
  • Methotrexate
  • Methyclothiazide
  • Metolazone
  • Moexipril
  • Mycophenolate
  • Nabumetone
  • Naproxen
  • Naproxen; Pseudoephedrine
  • Naproxen; Sumatriptan
  • Nateglinide
  • Nitazoxanide
  • Omeprazole; Amoxicillin; Rifabutin
  • Oxaprozin
  • Penicillin G Benzathine; Penicillin G Procaine
  • Penicillin G Procaine
  • Pentosan
  • Perindopril
  • Perindopril; Amlodipine
  • Phentermine; Topiramate
  • Phenytoin
  • Photosensitizing agents (topical)
  • Pioglitazone
  • Piroxicam
  • Polymyxins
  • Potassium Bicarbonate
  • Potassium Chloride
  • Potassium Citrate
  • Pramlintide
  • Prilocaine
  • Prilocaine; Epinephrine
  • Probenecid
  • Psyllium
  • Pyrazinamide, PZA
  • Quinapril
  • Ramipril
  • Repaglinide
  • Rifabutin
  • Rifampin
  • Rituximab; Hyaluronidase
  • Rivaroxaban
  • Ropivacaine
  • Rosiglitazone
  • Salicylic Acid
  • Saxagliptin
  • Serotonin norepinephrine reuptake inhibitors
  • Simvastatin; Sitagliptin
  • Sitagliptin
  • Sodium Hyaluronate, Hyaluronic Acid
  • Sodium Thiosulfate; Salicylic Acid
  • Spironolactone
  • Sulfinpyrazone
  • Sulfonamides
  • Sulindac
  • Tacrolimus
  • Telavancin
  • Tenofovir Alafenamide
  • Tenofovir, PMPA
  • Tetracaine
  • Thiazide diuretics
  • Thiazolidinediones
  • Thrombin Inhibitors
  • Thrombolytic Agents
  • Tinzaparin
  • Tolmetin
  • Topiramate
  • Torsemide
  • Trandolapril
  • Trandolapril; Verapamil
  • Trastuzumab; Hyaluronidase
  • Trazodone
  • Treprostinil
  • Triamterene
  • Valproic Acid, Divalproex Sodium
  • Vancomycin
  • Varicella-Zoster Virus Vaccine, Live
  • Vilazodone
  • Vortioxetine
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