Lutetium Lu 177 dotatate Brand Name– Lutathera What is Lutetium Lu 177 dotatate Lutetium Lu 177 dotatate is a radiolabeled somatostatin analog indicated for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in adults. Premedicate with antiemetics as well as an amino acid solution. Because lutetium Lu 177 dotatate is a radiopharmaceutical, appropriate safety …
Lusutrombopag Brand Name– MULPLETA What is Lusutrombopag Lusutrombopag is an oral thrombopoietin (TPO) receptor agonist indicated for the treatment of thrombocytopenia in adult patients with chronic liver disease who are scheduled to undergo a procedure. Lusutrombopag is not appropriate for use to normalize platelet counts in patients with chronic liver disease. Clinical trials enrolled patients …
Luspatercept Brand Name– REBLOZYL What is Luspatercept Luspatercept is an erythroid maturation agent. It is indicated for the treatment of anemia in adult patients with beta thalassemia who require regular red blood cell (RBC) transfusions and adult patients with very low- to intermediate-risk myelodysplastic syndromes (MDS) with ring sideroblasts or with MDS/myeloproliferative neoplasm with ring …
Lurbinectedin Brand Name– ZEPZELCA What is Lurbinectedin Lurbinectedin is an intravenous alkylating agent. It is indicated for the treatment of metastatic small cell lung cancer (SCLC) with disease progression on or after platinum-based chemotherapy. Treatment with lurbinectedin is associated with potentially severe myelosuppression; it is more common in patients 65 years of age or older. …
Lurasidone Brand Name– Latuda What is Lurasidone Lurasidone is an oral atypical antipsychotic belonging to the benzisoxazole/benzoisothiazol derivatives class. Atypical antipsychotics such as lurasidone are first-line treatment options for the management of schizophrenia and related disorders, with the exception of clozapine. Clinically, lurasidone is effective for the positive and negative symptoms of schizophrenia. Some atypical …
Lumateperone Brand Name– CAPLYTA What is Lumateperone Lumateperone is an oral atypical antipsychotic that has a dual action as a serotonin 5-HT2A receptor antagonist and a dopamine modulator. Lumateperone is indicated for the treatment of schizophrenia in adults. One advantage of lumateperone over most atypical antipsychotics is that dose titration is not required to reach …
Lumacaftor Ivacaftor Brand Name– ORKAMBI What is Lumacaftor Ivacaftor Lumacaftor ivacaftor is an orally available ion channel modulator approved for the treatment of cystic fibrosis (CF) in patients who are homozygous for the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The F508del mutation is the most frequent genotype in patients with CF; approximately 45% of …