What types of malignancies most often metastasize hematogenously to the GI tract?
Hematogenous metastatic spread of tumor to the bowel is usually seen in patients with widespread metastatic disease and is most commonly due to melanoma, lung cancer, and breast cancer. On cross-sectional imaging, multiple submucosal masses of the bowel wall are typically visualized, sometimes with areas of necrosis or ulceration. In the setting of metastatic breast cancer involving the stomach, a linitis plastica appearance of the stomach may be seen due to cellular infiltration of the gastric wall
