What sequelae have been associated with acute enteric infections?
A growing list of long-term and other sequelae have been associated with enteric infections. A strong link has been established mechanistically, epidemiologically, and from animal models between enteric infection and autoimmune phenomena like the Guillain-Barré syndrome (GBS) and reactive arthritis. During the last decade, epidemiologic evidence from outbreaks and large cohort studies has established a heightened risk of development of irritable bowel syndrome and other functional GI disorders after enteric infection. Most recently, emerging evidence suggests a potential link between some enteric infections and development or unmasking of celiac disease and IBDs.