Sepsis associated acute kidney injury

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What is sepsis associated acute kidney injury (SA AKI)

Sepsis associated acute kidney injury is characterized by the simultaneous presence of acute kidney injury (based on a consensus definition such as the Acute Kidney Injury Network [AKIN] or Kidney Disease Improving Global Outcomes [KDIGO] criteria; and the 2016 consensus criteria for sepsis (defined as life-threatening organ dysfunction caused by a dysregulated response to infection).

Causes of acute kidney injury not related to sepsis (e.g., nephrotoxic drugs or rhabdomyolysis) should be ruled out.

However, there is no standardized method for distinguishing Sepsis associated acute kidney injury from other causes of acute kidney injury, and in many cases the cause of acute kidney injury may be multifactorial and thus difficult to attribute to sepsis.

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