What enteric pathogens are associated with reactive arthritis?
Several enteric bacterial pathogens may be associated with postinfectious autoimmune arthritis syndromes. Salmonella, Yersinia, Campylobacter, and Shigella are most commonly associated. More recently, E. coli and C. difficile infection have been associated with arthralgia or arthritis syndromes as well. In addition to asymmetric oligoarthritis, some patients may develop conjunctivitis or skin eruptions (keratoderma blennorrhagica or erythema nodosum). Management includes the treatment of the inciting infection and then judicious use of antiinflammatory therapies (nonsteroidal antiinflammatory drugs, disease-modifying antirheumatic drugs, steroids).