Vascular consequence of vasculitis
Vasculitis is inflammation and necrosis of a blood vessel with subsequent impairment of blood flow. The vessel wall destruction leads to perforation and hemorrhage into adjacent tissues.
The endothelial injury leads to thrombosis and subsequent impairment of blood flow causing ischemia/infarction of dependent tissues.
Long-term consequences include accelerated secondary atherosclerosis of the involved vessel, which contributes to morbidity and mortality.