Treatment of vascular dementia

What is the treatment of vascular dementia? 

The FDA has not yet approved any drugs to treat vascular dementia, but research studies suggest that cholinesterase inhibitors and memantine may be helpful.

As for Alzheimers Disease, noncognitive behavioral effects of dementia are amenable to therapy, and respite care should be introduced early.

In addition, it is advisable to control vascular risk factors as much as possible (blood pressure, blood glucose, cholesterol, and hypertension).

Prophylactic antiplatelet therapy (aspirin, clopidogrel, or ticlopidine), although not of proven benefit for dementia, may be helpful by reducing the risk of future strokes. 


  • Román GC, Tatemichi, TK, Erkinjuntti T, Cummings JL, Masdeu JC, Garcia JH, et al.: Vascular dementia: diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43(2):250-260, 1993. 
  • Tatemichi TK, Desmond DW, Mayeux R, Paik M, Stern Y, Sano M, et al.: Dementia after stroke: baseline frequency, risks, and clinical features in a hospitalized cohort. Neurology 42(6):1185-1193, 1992.

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