Role of IVIG in CIDP

Role of IVIG in CIDP

The usefulness of IVIG in refractory and untreated CIDP has been confirmed by controlled studies.

IVIG usually is administered intravenously at a dose of 0.4 g/kg/day for 3 to 5 days or 1 g/kg/day for 2 days.

Benefits can be remarkable but are often short-lived (2 to 6 weeks), and stabilization of CIDP has been shown with regularly repeated infusions.

The two factors that predict the need for continuing IVIG therapy for more than 2 years are the presence of profound weakness when the therapy is initiated and an incomplete recovery with residual deficits after 6 months of treatment.

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