Immunosuppressive therapies for CIDP

Immunosuppressive therapies for CIDP

What immunosuppressive therapies are used in CIDP? 

The most common treatments for CIDP are corticosteroids, PE therapy, and high-dose IVIG.

Randomized controlled studies have demonstrated efficacy in CIDP for all three therapies and comparable efficacy has been shown.

Retrospective studies have shown that one-fourth of patients who are refractory to the standard treatments (i.e., IVIG, PE, or steroids) respond to another immunosuppressant. 

Other immunosuppressives considered for CIDP include cyclophosphamide, cyclosporine, mycophenolate mofetil, interferon-β, interferon-α, methotrexate, etanercept, rituximab, alemtuzumab, tacrolimus, and azathioprine.

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