Hereditary papillary renal cell carcinoma

Features of Hereditary papillary renal cell carcinoma

Hereditary papillary renal cell carcinoma is characterized by mutations in the MET proto-oncogene, located at 7q31.

The mutations are highly penetrant and autosomal dominant.

The resulting tumors are classified as papillary type 1 and are often multifocal and bilateral.

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