Tafluprost

What is Tafluprost

Tafluprost is a prostaglandin analog with a high affinity for the fluoroprostaglandin (FP) receptor.

It is indicated for reducing elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

In clinical studies, administration of tafluprost 0.0015% once daily to patients with open-angle glaucoma or ocular hypertension and a baseline IOP of 23—26 mmHg resulted in an IOP decrease of approximately 6—8 mmHg after 3 months and 5—8 mmHg after 6 months.

Brand Name

ZIOPTAN

Indications

• glaucoma
• increased intraocular pressure
• ocular hypertension

For the reduction of increased intraocular pressure in patients with open-angle glaucoma or ocular hypertension.

Side Effects

1. blurred vision
2. cataracts
3. conjunctival hyperemia
4. conjunctivitis
5. cough
6. dyspnea
7. headache
8. infection
9. iridal discoloration
10. iritis
11. macular edema
12. ocular irritation
13. ocular pain
14. ocular pruritus
15. skin hyperpigmentation
16. uveitis
17. xerophthalmia

Monitoring Parameters

• intraocular pressure
• ophthalmologic exam

Contraindications

• aphakia
• breast-feeding
• children
• infants
• inflammation
• iritis
• neonates
• pregnancy
• uveitis

Interactions

There are no drug interactions associated with Tafluprost products.