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What is Sulfinpyrazone
Sulfinpyrazone is an oral uricosuric agent (pyrazolone derivative) used to treat chronic or intermittent gouty arthritis.
Sulfinpyrazone is not intended for the treatment of acute attacks because it lacks therapeutically useful analgesic and anti-inflammatory effects.
Brand Name
Anturane
Side Effects
- agranulocytosis
- anemia
- aplastic anemia
- arthralgia
- bronchospasm
- dyspepsia
- edema
- gastritis
- GI bleeding
- hematuria
- interstitial nephritis
- leukopenia
- nausea
- nephrolithiasis
- rash
- renal failure (unspecified)
- renal tubular obstruction
- thrombocytopenia
- tinnitus
- vertigo
- vomiting
Monitoring Parameters
- CBC
- serum creatinine
- serum uric acid
Contraindications
- agranulocytosis
- anemia
- anticoagulant therapy
- bone marrow suppression
- breast-feeding
- gastritis
- geriatric
- hematological disease
- hepatic disease
- leukopenia
- nephrolithiasis
- NSAID hypersensitivity
- peptic ulcer disease
- pregnancy
- renal disease
- renal failure
- renal impairment
- salicylate hypersensitivity
- thrombocytopenia
Interactions
- Abciximab
- Acetaminophen
- Acetaminophen; Aspirin, ASA; Caffeine
- Acetaminophen; Butalbital
- Acetaminophen; Butalbital; Caffeine
- Acetaminophen; Butalbital; Caffeine; Codeine
- Acetaminophen; Caffeine
- Acetaminophen; Caffeine; Dihydrocodeine
- Acetaminophen; Caffeine; Magnesium Salicylate; Phenyltoloxamine
- Acetaminophen; Caffeine; Phenyltoloxamine; Salicylamide
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Phenylephrine
- Acetaminophen; Chlorpheniramine; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Chlorpheniramine; Phenylephrine; Phenyltoloxamine
- Acetaminophen; Codeine
- Acetaminophen; Dextromethorphan
- Acetaminophen; Dextromethorphan; Doxylamine
- Acetaminophen; Dextromethorphan; Guaifenesin; Phenylephrine
- Acetaminophen; Dextromethorphan; Phenylephrine
- Acetaminophen; Dextromethorphan; Pseudoephedrine
- Acetaminophen; Dichloralphenazone; Isometheptene
- Acetaminophen; Diphenhydramine
- Acetaminophen; Guaifenesin; Phenylephrine
- Acetaminophen; Hydrocodone
- Acetaminophen; Oxycodone
- Acetaminophen; Pentazocine
- Acetaminophen; Propoxyphene
- Acetaminophen; Pseudoephedrine
- Acetaminophen; Tramadol
- Allopurinol
- Aminosalicylate sodium, Aminosalicylic acid
- Anagrelide
- Anticoagulants
- Antithrombin III
- Apixaban
- Argatroban
- Aspirin, ASA
- Aspirin, ASA; Butalbital; Caffeine
- Aspirin, ASA; Butalbital; Caffeine; Codeine
- Aspirin, ASA; Caffeine; Dihydrocodeine
- Aspirin, ASA; Caffeine; Orphenadrine
- Aspirin, ASA; Carisoprodol
- Aspirin, ASA; Carisoprodol; Codeine
- Aspirin, ASA; Citric Acid; Sodium Bicarbonate
- Aspirin, ASA; Dipyridamole
- Aspirin, ASA; Omeprazole
- Aspirin, ASA; Oxycodone
- Aspirin, ASA; Pravastatin
- Atropine; Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Benzhydrocodone; Acetaminophen
- Benzoic Acid; Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate
- Betrixaban
- Bismuth Subsalicylate
- Bismuth Subsalicylate; Metronidazole; Tetracycline
- Bivalirudin
- Bosentan
- Cholestyramine
- Choline Salicylate; Magnesium Salicylate
- Cilostazol
- Clopidogrel
- Colchicine
- Colchicine; Probenecid
- Cyclosporine
- Dabigatran
- Dalteparin
- Danaparoid
- Desirudin
- Diazoxide
- Dipyridamole
- Dronabinol
- Edoxaban
- Enoxaparin
- Eptifibatide
- Ethacrynic Acid
- Ethambutol
- Fluvastatin
- Fondaparinux
- food
- Fosphenytoin
- Glimepiride; Rosiglitazone
- Guanidine
- Heparin
- Hydrochlorothiazide, HCTZ; Triamterene
- Hydroxyurea
- Hyoscyamine; Methenamine; Methylene Blue; Phenyl Salicylate; Sodium Biphosphate
- Insulins
- Isoniazid, INH; Pyrazinamide, PZA; Rifampin
- Lepirudin
- Lesinurad
- Lesinurad; Allopurinol
- Magnesium Salicylate
- Mecamylamine
- Metformin; Rosiglitazone
- Mycophenolate
- Nateglinide
- Nitrofurantoin
- Nonsteroidal antiinflammatory drugs
- Pegloticase
- Pentosan
- Phenytoin
- Platelet Inhibitors
- Prasugrel
- Probenecid
- Pyrazinamide, PZA
- Ramelteon
- Rivaroxaban
- Rosiglitazone
- Salicylates
- Salsalate
- Sulfamethoxazole; Trimethoprim, SMX-TMP, Cotrimoxazole
- Sulfisoxazole
- Sulfonylureas
- Terbinafine
- Theophylline, Aminophylline
- Thiazide diuretics
- Thrombolytic Agents
- Ticagrelor
- Ticlopidine
- Tinzaparin
- Tirofiban
- Trandolapril; Verapamil
- Triamterene
- Verapamil
- Vorapaxar
- Voriconazole
- Warfarin
